Претраживање
Приказ резултата 41-50 од 70
CD22 regulates early B cell development in BOB.1/OBF.1-deficient mice
(Wiley-V C H Verlag Gmbh, Weinheim, 2002)
BOB.1/OBF1 (also called OCA-B), a B lymphocyte-specific transcriptional coactivator, is recruited to octamer-containing promoters by interacting with the Oct-1 or Oct-2 proteins. BOB.1/OBF.1-deficient mice show impaired ...
c-MYC activation impairs the NF-kappa B and the interferon response: Implications for the pathogenesis of Burkitt's lymphoma
(Wiley-Liss, Hoboken, 2007)
Deregulation of the proto-oncogene c-myc is a key event in the pathogenesis of many tumors. A paradigm is the activation of the c-myc gene by chromosomal translocations in Burkitt lymphoma (BL). Despite expression of a ...
B cell hyperresponsiveness and expansion of mature follicular B cells but not of marginal zone B cells in NFATc2/c3 double-deficient mice
(Amer Assoc Immunologists, Bethesda, 2005)
Marginal zone (MZ) B cells and peritoneal B-I cells provide a first defense system of thymus-independent Ab responses against foreign pathogens and therefore share a number of functional properties. Recently, development ...
Traumatic brain injury: neuropathological, neurocognitive and neurobehavioral sequelae
(Springer, New York, 2019)
Traumatic brain injury (TBI) causes substantial neurological disabilities and mental distress. Annual TBI incidence is in magnitude of millions, making it a global health challenge. Categorization of TBI into severe, ...
Individual differences in cognitive biases: Evidence against one-factor theory of rationality
(Elsevier Science Inc, New York, 2015)
In this paper we seek to gain an improved understanding of the structure of cognitive biases and their relationship with measures of intelligence and relevant non-cognitive constructs. We report on the outcomes of a study ...
Cerebrovascular disease in patients with cognitive impairment: A white paper from the ESO dementia committee - A practical point of view with suggestions for the management of cerebrovascular diseases in memory clinics
(Sage Publications Ltd, London, 2021)
Purpose: Practical suggestions on clinical decisions about vascular disease management in patients with cognitive impairment are proposed. Methods: The document was produced by the Dementia Committee of the European Stroke ...
Identification of novel Myc target genes with a potential role in lymphomagenesis
(Oxford Univ Press, Oxford, 2004)
The c-Myc transcription factor regulates a wide set of genes involved in processes such as proliferation, differentiation and apoptosis. Therefore, altered expression of Myc leads to deregulation of a large number of target ...
Differential activation of anti-erythrocyte and anti-DNA autoreactive B lymphocytes by the Yaa mutation
(Amer Assoc Immunologists, Bethesda, 2005)
An as-yet-unidentified mutation, Y-linked autoimmune acceleration (Yaa), is responsible for the accelerated development of lupus-like autoimmune syndrome in mice. In view of a possible role for Yaa as a positive regulator ...
Conditions of living and social skills of children with mild intellectual disability
(Wiley, Hoboken, 2006)