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BOB.1OBF.1 deficiency affects marginal-zone B-cell compartment
(Amer Soc Microbiology, Washington, 2002)
Marginal-zone (MZ) B cells represent a first line of defense against particulate blood-borne antigens. Together with the B1 cells, they are responsible for the early response against type It T-independent antigens. The ...
AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation
(Amer Soc Hematology, Washington, 2006)
AKT serine threonine kinase of the protein kinase B (PKB) family plays essential roles in cell survival, growth, metabolism, and differentiation. In the erythroid system, AKT is known to be rapidly phosphorylated and ...
Myc Regulates Embryonic Vascular Permeability and Remodeling
(Lippincott Williams & Wilkins, Philadelphia, 2009)
Previous work has shown that c-Myc is required for adequate vasculogenesis and angiogenesis. To further investigate the contribution of Myc to these processes, we conditionally expressed c-Myc in embryonic endothelial cells ...
The Yaa mutation promoting murine lupus causes defective development of marginal zone B cells
(Amer Assoc Immunologists, Bethesda, 2003)
The accelerated development of systemic lupus erythematosus (SLE) in BXSB male mice is associated with the presence of an as yet unidentified mutant gene, Yaa (Y-linked autoimmune acceleration). In view of a possible role ...
B cell-specific transgenic expression of Bcl2 rescues early B lymphopoiesis but not B cell responses in BOB.1/OBF.1-deficient mice
(Rockefeller Univ Press, New York, 2003)
Mice deficient for the transcriptional coactivator BOB.1/OBF.1 show several defects in B cell differentiation. Numbers of immature transitional B cells in the bone marrow are reduced and fewer B cells reach the periphery. ...
The quality of life and psychiatric morbidity after decompression surgery in patients with arnold-chiari malformation-I
(Cambridge Univ Press, New York, 2010)
Flexibility of attention in children with intellectual disabilities
(Cambridge Univ Press, New York, 2010)
Attentional scope in children with intellectual disabilities
(Cambridge Univ Press, New York, 2010)
Children with intellectual disorder and their perception
(Cambridge Univ Press, New York, 2010)
Monitoring the effects of the treatment in rehabilitation of children with intellectual disabilities and attention disorders
(Cambridge Univ Press, New York, 2008)