Претраживање
Приказ резултата 1-2 од 2
The Yaa mutation promoting murine lupus causes defective development of marginal zone B cells
(Amer Assoc Immunologists, Bethesda, 2003)
The accelerated development of systemic lupus erythematosus (SLE) in BXSB male mice is associated with the presence of an as yet unidentified mutant gene, Yaa (Y-linked autoimmune acceleration). In view of a possible role ...
B cell-specific transgenic expression of Bcl2 rescues early B lymphopoiesis but not B cell responses in BOB.1/OBF.1-deficient mice
(Rockefeller Univ Press, New York, 2003)
Mice deficient for the transcriptional coactivator BOB.1/OBF.1 show several defects in B cell differentiation. Numbers of immature transitional B cells in the bone marrow are reduced and fewer B cells reach the periphery. ...