Претраживање
Приказ резултата 1-10 од 15
BOB.1OBF.1 deficiency affects marginal-zone B-cell compartment
(Amer Soc Microbiology, Washington, 2002)
Marginal-zone (MZ) B cells represent a first line of defense against particulate blood-borne antigens. Together with the B1 cells, they are responsible for the early response against type It T-independent antigens. The ...
The Yaa mutation promoting murine lupus causes defective development of marginal zone B cells
(Amer Assoc Immunologists, Bethesda, 2003)
The accelerated development of systemic lupus erythematosus (SLE) in BXSB male mice is associated with the presence of an as yet unidentified mutant gene, Yaa (Y-linked autoimmune acceleration). In view of a possible role ...
AKT induces erythroid-cell maturation of JAK2-deficient fetal liver progenitor cells and is required for Epo regulation of erythroid-cell differentiation
(Amer Soc Hematology, Washington, 2006)
AKT serine threonine kinase of the protein kinase B (PKB) family plays essential roles in cell survival, growth, metabolism, and differentiation. In the erythroid system, AKT is known to be rapidly phosphorylated and ...
B cell-specific transgenic expression of Bcl2 rescues early B lymphopoiesis but not B cell responses in BOB.1/OBF.1-deficient mice
(Rockefeller Univ Press, New York, 2003)
Mice deficient for the transcriptional coactivator BOB.1/OBF.1 show several defects in B cell differentiation. Numbers of immature transitional B cells in the bone marrow are reduced and fewer B cells reach the periphery. ...
Foxo3 transcription factor regulates oxidative stress in in vivo erythropoiesis.
(Amer Soc Hematology, Washington, 2006)
Myc Regulates Embryonic Vascular Permeability and Remodeling
(Lippincott Williams & Wilkins, Philadelphia, 2009)
Previous work has shown that c-Myc is required for adequate vasculogenesis and angiogenesis. To further investigate the contribution of Myc to these processes, we conditionally expressed c-Myc in embryonic endothelial cells ...
Recovery after severe brain injury
(Lippincott Williams & Wilkins, Philadelphia, 2008)
Oxidative Stress-Mediated Activation of AKT/mTOR Signaling Pathway Leads to Myeloproliferative Syndrome in FoxO3 Null Mice: A Role for Lnk Adaptor Protein
(Amer Soc Hematology, Washington, 2008)
Semantic and Syntactic Development in Preschool Children
(Lippincott Williams & Wilkins, Philadelphia, 2009)
Detection and prevalence of motor skill disorders
(Pergamon-Elsevier Science Ltd, Oxford, 2009)
The main goal of this research was to establish the prevalence, form of manifestation, level and kind of motor skill disorders in three area of motor development functioning: neuromaturation, coordination and balance. The ...