TY  - JOUR
AU  - Đorđević, Jelena
AU  - Pavlović, Aleksandra
AU  - Mihajlović, Goran
AU  - Hinić, Darko
AU  - Vojvodić, Jovana
AU  - Živanović, Marko
AU  - Pavlović, Dragan
PY  - 2024
UR  - https://doiserbia.nb.rs/Article.aspx?ID=0048-57052400006D
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/5410
AB  - Theory of Mind (ToM) is a social-cognitive ability to understand the mental states of others. ToM functions are compromised in the case of mental disorders characterized by cognitive impairments. The Faux Pas Recognition test (FPRT) is considered a good measure of verbal aspects of ToM as it measures social adaptation through the adequate interpretation of potentially sensitive and awkward social situations. However, data on FPRT psychometric properties is somewhat limited. The aim of the present study is the psychometric evaluation of the FPRT in Serbian population. The adapted version in Serbian has been administered to 268 healthy participants, 30 patients with schizophrenia and 31 with bipolar affective disorder. The results show a high internal consistencies of Faux Pas stories (α = .954), Control stories (α = .929) and overall test (α = .936). Both Horn’s parallel analysis and confirmatory factor analysis indicated that a single-factor solution is optimal, supporting the premise of a general ToM ability underlying performance across test. The Faux Pas test showed good discriminative power in differentiation between individuals from healthy and clinical populations making it a useful clinical instrument.
PB  - Serbian Psychological Society
T2  - Psihologija
T2  - Psihologija
T1  - Assessing theory of mind abilities in schizophrenia and bipolar disorder: A psychometric study of the Faux Pas Recognition test in Serbian
EP  - 6
IS  - 00
SP  - 6
DO  - https://doi.org/10.2298/PSI220824006D
DO  - https://doi.org/10.2298/PSI220824006D
ER  - 

@article{
author = "Đorđević, Jelena and Pavlović, Aleksandra and Mihajlović, Goran and Hinić, Darko and Vojvodić, Jovana and Živanović, Marko and Pavlović, Dragan",
year = "2024",
abstract = "Theory of Mind (ToM) is a social-cognitive ability to understand the mental states of others. ToM functions are compromised in the case of mental disorders characterized by cognitive impairments. The Faux Pas Recognition test (FPRT) is considered a good measure of verbal aspects of ToM as it measures social adaptation through the adequate interpretation of potentially sensitive and awkward social situations. However, data on FPRT psychometric properties is somewhat limited. The aim of the present study is the psychometric evaluation of the FPRT in Serbian population. The adapted version in Serbian has been administered to 268 healthy participants, 30 patients with schizophrenia and 31 with bipolar affective disorder. The results show a high internal consistencies of Faux Pas stories (α = .954), Control stories (α = .929) and overall test (α = .936). Both Horn’s parallel analysis and confirmatory factor analysis indicated that a single-factor solution is optimal, supporting the premise of a general ToM ability underlying performance across test. The Faux Pas test showed good discriminative power in differentiation between individuals from healthy and clinical populations making it a useful clinical instrument.",
publisher = "Serbian Psychological Society",
journal = "Psihologija, Psihologija",
title = "Assessing theory of mind abilities in schizophrenia and bipolar disorder: A psychometric study of the Faux Pas Recognition test in Serbian",
pages = "6-6",
number = "00",
doi = "https://doi.org/10.2298/PSI220824006D, https://doi.org/10.2298/PSI220824006D"
}

Đorđević, J., Pavlović, A., Mihajlović, G., Hinić, D., Vojvodić, J., Živanović, M.,& Pavlović, D.. (2024). Assessing theory of mind abilities in schizophrenia and bipolar disorder: A psychometric study of the Faux Pas Recognition test in Serbian. in Psihologija
Serbian Psychological Society.(00), 6-6.
https://doi.org/https://doi.org/10.2298/PSI220824006D

Đorđević J, Pavlović A, Mihajlović G, Hinić D, Vojvodić J, Živanović M, Pavlović D. Assessing theory of mind abilities in schizophrenia and bipolar disorder: A psychometric study of the Faux Pas Recognition test in Serbian. in Psihologija. 2024;(00):6-6.
doi:https://doi.org/10.2298/PSI220824006D .

Đorđević, Jelena, Pavlović, Aleksandra, Mihajlović, Goran, Hinić, Darko, Vojvodić, Jovana, Živanović, Marko, Pavlović, Dragan, "Assessing theory of mind abilities in schizophrenia and bipolar disorder: A psychometric study of the Faux Pas Recognition test in Serbian" in Psihologija, no. 00 (2024):6-6,
https://doi.org/https://doi.org/10.2298/PSI220824006D . .

TY  - CONF
AU  - Pavlović, Dragan
AU  - Pavlović, Aleksandra
PY  - 2023
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/5399
AB  - Ментална хигијена је приступ очувању менталног здравља кроз различите
методе са вишеструким циљевима. Једна од најзначајних метода је физичка
активност. Ефекти физичке активности на когницију су позитивни од раног
детињства до сенијума. Показано је да вежбање побољшава расположење и
самопоуздање смањује негативне ефекте стреса, делује против депресије и анксиозности.
На
молекуларном
нивоу
физичка
активност
регулише
рад
хипоталамо-хипофизно-адреналне
осовине,
повећава
стварање
опиоида
и
ендоканабиноида,
док
је
главни
главни
механизам
повећано
лучење
неуротрофичког
фактора

можданог
порекла
(brain
derived
neurotrophic
factor
-
BDNF).
Физичка
активност

подстиче
когницију,
смањује
симптоме
депресије
и
анксиозности
код
деце
и
адолесцената
и
њихово
схоластичко
постигнуће.
Више
студија
је
испитивало
утицај

физичке
активности
код
предшколске
деце
на
когницију
и
емоције.
Резултати
су

углавном
позитивни
и
указују
на
потребу
веће
заступљеност
физичке
активности,
слободне
и
организоване
код
предшколске
деце
са
повољним
ефектима
на

њихов
когнитивни
и
емоционални
развој.
Посебно
су
изучавана
деца
са
интелектуалним
сметњама
у
погледу
ефеката
физичке
активности
на
њихово
ментално
здравље.
Студије
указују
на
значај
примене
метода
физичке
активности
код

деце
са
поремећајем
из
спектра
аутизма
и
егзекутивне
функције
код
развојног

поремећаја
координације.
AB  - Mental hygiene is an approach to maintaining
mental health through various methods with
multiple goals. One of the most important
methods is physical activity. The effects of
physical activity on cognition are positive
from early childhood to old age. Exercise
improves mood and self-confidence, reduces
the negative effects of stress, acts against
depression and anxiety. At the molecular level,
physical activity regulates the hypothalamicpituitary-adrenal

axis, increases the
production of opioids and endocannabinoids,
while the main mechanism is increased
secretion of brain-derived neurotrophic
factor (BDNF). Physical activity improves cognition, reduces symptoms of depression
and anxiety in children and adolescents and
their scholastic achievement. Several studies
have examined the impact of physical activity
in preschool children on cognition and
emotions. The results are mostly positive and
indicate the need for greater representation
of physical activity, free and organized,
among preschool children with favorable 
effects on their cognitive and emotional 
development. In particular, intellectually
disabled children were studied in terms of the
effects of physical activity on their mental
health. Studies indicate the importance
of applying physical activity methods in
children with autistic spectrum disorders
and executive function in developmental
coordination disorder.
PB  - Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju University of Belgrade – Faculty of Special Education and Rehabilitation
C3  - Национални научни скуп „Интервенције у раном детињству и предшколству” Београд, 22. децембар 2023. Зборник радова
T1  - Mентална хигијена и физичка активност здраве деце и деце са интелектуалном ометеношћу
T1  - Mental hygiene and physical activity of healthy children and children with intellectual disabilities
EP  - 64
SP  - 57
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_5399
ER  - 

@conference{
author = "Pavlović, Dragan and Pavlović, Aleksandra",
year = "2023",
abstract = "Ментална хигијена је приступ очувању менталног здравља кроз различите
методе са вишеструким циљевима. Једна од најзначајних метода је физичка
активност. Ефекти физичке активности на когницију су позитивни од раног
детињства до сенијума. Показано је да вежбање побољшава расположење и
самопоуздање смањује негативне ефекте стреса, делује против депресије и анксиозности.
На
молекуларном
нивоу
физичка
активност
регулише
рад
хипоталамо-хипофизно-адреналне
осовине,
повећава
стварање
опиоида
и
ендоканабиноида,
док
је
главни
главни
механизам
повећано
лучење
неуротрофичког
фактора

можданог
порекла
(brain
derived
neurotrophic
factor
-
BDNF).
Физичка
активност

подстиче
когницију,
смањује
симптоме
депресије
и
анксиозности
код
деце
и
адолесцената
и
њихово
схоластичко
постигнуће.
Више
студија
је
испитивало
утицај

физичке
активности
код
предшколске
деце
на
когницију
и
емоције.
Резултати
су

углавном
позитивни
и
указују
на
потребу
веће
заступљеност
физичке
активности,
слободне
и
организоване
код
предшколске
деце
са
повољним
ефектима
на

њихов
когнитивни
и
емоционални
развој.
Посебно
су
изучавана
деца
са
интелектуалним
сметњама
у
погледу
ефеката
физичке
активности
на
њихово
ментално
здравље.
Студије
указују
на
значај
примене
метода
физичке
активности
код

деце
са
поремећајем
из
спектра
аутизма
и
егзекутивне
функције
код
развојног

поремећаја
координације., Mental hygiene is an approach to maintaining
mental health through various methods with
multiple goals. One of the most important
methods is physical activity. The effects of
physical activity on cognition are positive
from early childhood to old age. Exercise
improves mood and self-confidence, reduces
the negative effects of stress, acts against
depression and anxiety. At the molecular level,
physical activity regulates the hypothalamicpituitary-adrenal

axis, increases the
production of opioids and endocannabinoids,
while the main mechanism is increased
secretion of brain-derived neurotrophic
factor (BDNF). Physical activity improves cognition, reduces symptoms of depression
and anxiety in children and adolescents and
their scholastic achievement. Several studies
have examined the impact of physical activity
in preschool children on cognition and
emotions. The results are mostly positive and
indicate the need for greater representation
of physical activity, free and organized,
among preschool children with favorable 
effects on their cognitive and emotional 
development. In particular, intellectually
disabled children were studied in terms of the
effects of physical activity on their mental
health. Studies indicate the importance
of applying physical activity methods in
children with autistic spectrum disorders
and executive function in developmental
coordination disorder.",
publisher = "Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju University of Belgrade – Faculty of Special Education and Rehabilitation",
journal = "Национални научни скуп „Интервенције у раном детињству и предшколству” Београд, 22. децембар 2023. Зборник радова",
title = "Mентална хигијена и физичка активност здраве деце и деце са интелектуалном ометеношћу, Mental hygiene and physical activity of healthy children and children with intellectual disabilities",
pages = "64-57",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_5399"
}

Pavlović, D.,& Pavlović, A.. (2023). Mентална хигијена и физичка активност здраве деце и деце са интелектуалном ометеношћу. in Национални научни скуп „Интервенције у раном детињству и предшколству” Београд, 22. децембар 2023. Зборник радова
Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju University of Belgrade – Faculty of Special Education and Rehabilitation., 57-64.
https://hdl.handle.net/21.15107/rcub_rfasper_5399

Pavlović D, Pavlović A. Mентална хигијена и физичка активност здраве деце и деце са интелектуалном ометеношћу. in Национални научни скуп „Интервенције у раном детињству и предшколству” Београд, 22. децембар 2023. Зборник радова. 2023;:57-64.
https://hdl.handle.net/21.15107/rcub_rfasper_5399 .

Pavlović, Dragan, Pavlović, Aleksandra, "Mентална хигијена и физичка активност здраве деце и деце са интелектуалном ометеношћу" in Национални научни скуп „Интервенције у раном детињству и предшколству” Београд, 22. децембар 2023. Зборник радова (2023):57-64,
https://hdl.handle.net/21.15107/rcub_rfasper_5399 .

TY  - CONF
AU  - Pavlović, Dragan
AU  - Pavlović, Aleksandra
PY  - 2023
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/5387
AB  - Uvod: Vitamin B12 ili kobalamin je hidrosolubilni vitamin koji učestvuje u
stvaranju kateholamina, dezoksiribonukleinske kiseline, mijelina i u hematopoezi.

On je esencijalan faktor u intrauterinom razvoju mozga i mijelinizaciji
sve do puberteta, pa i kasnije. Ljudski organizam nema sposobnost sinteze
kobalamina, pa je zavistan od unosa ishranom ili supstitucijom.
Cilj: Pregled savremene literature o deficijenciji vitamina B12 kod dece i adolescenata,
prikaz
tipične
kliničke
slike i
diskusija
terapijskih
pristupa.
Metode:
Pretraga
elektronskih
baza
podataka
u
sklopu
servisa
Konzorcijuma
biblioteka
Srbije
za
objedinjenu
nabavku
(KOBSON)
sa
ključnim
rečima:
vitamin

B12,
kobalamin,
deficijencija,
deca,
adolescenti.
Rezultati:
Deficit
vitamina
B12
je
čest
među
decom
i
omladinom
u
zemlјama

u
razvoju,
ali
sve
češće
i
u
razvijenim
zemljama.
Kod
dece
postoje
tri
osnovna
uzroka
deficijencije:
1.
smanjen
unos,
2.
poremećaj
resorpcije,

3. urođeni
poremećaji transporta i metabolizma. Snižen nivo vitamina B12 u krvi
povezan je sa negativnim ishodom trudnoće po majku i dete, podižući rizik
za
razvojne
anomalije,
spontani
pobačaj,
preeklampsiju
i
nisku
težinu
deteta
na
rođenju.
Neuropsihološke
posledice
kod
dece
su
kognitivni
poremećaji

(smetnje
pažnje,
pamćenja
i
sniženje
akademskog
postignuća),
izmene
afekta

i
ponašanja.
Nekoliko
kohortnih
studija
pokazalo
je
povezanost
nivoa
vitamina

B12 u krvi ili zastupljenost u ishrani majke sa kognitivnim ishodima kod
dece. Međutim, najveći broj do sada objavljenih studija o negativnom uticaju
sniženog nivoa vitamina B12 na kognitivni status dece je opservacionog tipa,
te ne mogu potvrditi kauzalnu povezanost. Dijagnoza deficita vitamina B12
zasniva se na kliničkoj slici, neurološkom i psihijatrijskom nalazu, ispitivanju
kognicije i laboratorijskoj dijagnostici, koja obuhvata cirkulatorne i funkcionalne
biomarkere.
Nadoknada
deficita
kobalamina
je
podjednako
efikasna
i

parenteralno i
oralno,
ukoliko se
daju
adekvatne
doze.
Zaključak:
Nedostatak
vitamina
B12
je
relativno
čest
među
decom
i
omladinom
i
dovodi
do
neuroloških
i
psihijatrijskih
smetnji
koje,
ako
se
ne
leče,
mogu

dovesti
do
ireverzibilnih
promena.
AB  - Introduction: Vitamin B12, also known as cobalamin, is a water- soluble vitamin
that participates in the synthesis of catecholamines, deoxyribonucleic acid, myelin, and
hematopoiesis. It is an essential factor in the intrauterine development of the brain and
myelination, extending through puberty, and later on in life. The human body lacks the
ability to synthesize cobalamin, thus depending on dietary intake or supplementation.
Aim: Review of current literature on vitamin B12 deficiency in children and adolescents,
typical presentation and therapeutic approach.
Methods: Literature search via electronic database within the Serbian Library
Consortium for Coordinated Acquisition (KOBSON) with keywords: vitamin B12, cobalamin,
deficiency, children, adolescents.
Results: Vitamin B12 deficiency is common among children and adolescents in
developing countries, but it is becoming increasingly prevalent in developed countries as well. In children, there are three main causes of deficiency: 1. Reduced intake, 2. Impaired
absorption, 3. Inherited transport and metabolism disorders. Decreased levels of vitamin B12
in the blood are associated with adverse outcomes for both the mother and child during
pregnancy, increasing the risk of developmental abnormalities, spontaneous abortion,
preeclampsia, and low birth weight. Neuropsychological consequences in children include
cognitive disorders (attention deficits, memory impairments, and decreased academic
achievement), changes in mood, and behavior. Several cohort studies have shown an
association between vitamin B12 levels in the blood or maternal dietary intake and cognitive
outcomes in children. However, the majority of published studies on the negative impact of
low vitamin B12 levels on the cognitive status of children are observational in nature and
cannot confirm a causal relationship. The diagnosis of vitamin B12 deficiency is based on
clinical presentation, neurological and psychiatric findings, cognitive testing, and laboratory
diagnostics, which include circulating and functional biomarkers. Replenishment of
cobalamin deficiency is equally effective via parenteral and oral routes if adequate doses are
administered.
Conclusion: Vitamin B12 deficiency is relatively common among children and adolescents,
and it leads to neurological and psychiatric impairments that, if left untreated, can result in
irreversible changes.
PB  - Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju University of Belgrade – Faculty of Special Education and Rehabilitation
C3  - Zbornik radova - 12. Međunarodni naučni skup Specijalna edukacija i rehabilitacija danas Beograd, 27–28. oktobar 2023. Godine
T1  - Status vitamina b12 i razvoj dece
T1  - Vitamin b12 status and development in children and adolescents
EP  - 587
SP  - 581
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_5387
ER  - 

@conference{
author = "Pavlović, Dragan and Pavlović, Aleksandra",
year = "2023",
abstract = "Uvod: Vitamin B12 ili kobalamin je hidrosolubilni vitamin koji učestvuje u
stvaranju kateholamina, dezoksiribonukleinske kiseline, mijelina i u hematopoezi.

On je esencijalan faktor u intrauterinom razvoju mozga i mijelinizaciji
sve do puberteta, pa i kasnije. Ljudski organizam nema sposobnost sinteze
kobalamina, pa je zavistan od unosa ishranom ili supstitucijom.
Cilj: Pregled savremene literature o deficijenciji vitamina B12 kod dece i adolescenata,
prikaz
tipične
kliničke
slike i
diskusija
terapijskih
pristupa.
Metode:
Pretraga
elektronskih
baza
podataka
u
sklopu
servisa
Konzorcijuma
biblioteka
Srbije
za
objedinjenu
nabavku
(KOBSON)
sa
ključnim
rečima:
vitamin

B12,
kobalamin,
deficijencija,
deca,
adolescenti.
Rezultati:
Deficit
vitamina
B12
je
čest
među
decom
i
omladinom
u
zemlјama

u
razvoju,
ali
sve
češće
i
u
razvijenim
zemljama.
Kod
dece
postoje
tri
osnovna
uzroka
deficijencije:
1.
smanjen
unos,
2.
poremećaj
resorpcije,

3. urođeni
poremećaji transporta i metabolizma. Snižen nivo vitamina B12 u krvi
povezan je sa negativnim ishodom trudnoće po majku i dete, podižući rizik
za
razvojne
anomalije,
spontani
pobačaj,
preeklampsiju
i
nisku
težinu
deteta
na
rođenju.
Neuropsihološke
posledice
kod
dece
su
kognitivni
poremećaji

(smetnje
pažnje,
pamćenja
i
sniženje
akademskog
postignuća),
izmene
afekta

i
ponašanja.
Nekoliko
kohortnih
studija
pokazalo
je
povezanost
nivoa
vitamina

B12 u krvi ili zastupljenost u ishrani majke sa kognitivnim ishodima kod
dece. Međutim, najveći broj do sada objavljenih studija o negativnom uticaju
sniženog nivoa vitamina B12 na kognitivni status dece je opservacionog tipa,
te ne mogu potvrditi kauzalnu povezanost. Dijagnoza deficita vitamina B12
zasniva se na kliničkoj slici, neurološkom i psihijatrijskom nalazu, ispitivanju
kognicije i laboratorijskoj dijagnostici, koja obuhvata cirkulatorne i funkcionalne
biomarkere.
Nadoknada
deficita
kobalamina
je
podjednako
efikasna
i

parenteralno i
oralno,
ukoliko se
daju
adekvatne
doze.
Zaključak:
Nedostatak
vitamina
B12
je
relativno
čest
među
decom
i
omladinom
i
dovodi
do
neuroloških
i
psihijatrijskih
smetnji
koje,
ako
se
ne
leče,
mogu

dovesti
do
ireverzibilnih
promena., Introduction: Vitamin B12, also known as cobalamin, is a water- soluble vitamin
that participates in the synthesis of catecholamines, deoxyribonucleic acid, myelin, and
hematopoiesis. It is an essential factor in the intrauterine development of the brain and
myelination, extending through puberty, and later on in life. The human body lacks the
ability to synthesize cobalamin, thus depending on dietary intake or supplementation.
Aim: Review of current literature on vitamin B12 deficiency in children and adolescents,
typical presentation and therapeutic approach.
Methods: Literature search via electronic database within the Serbian Library
Consortium for Coordinated Acquisition (KOBSON) with keywords: vitamin B12, cobalamin,
deficiency, children, adolescents.
Results: Vitamin B12 deficiency is common among children and adolescents in
developing countries, but it is becoming increasingly prevalent in developed countries as well. In children, there are three main causes of deficiency: 1. Reduced intake, 2. Impaired
absorption, 3. Inherited transport and metabolism disorders. Decreased levels of vitamin B12
in the blood are associated with adverse outcomes for both the mother and child during
pregnancy, increasing the risk of developmental abnormalities, spontaneous abortion,
preeclampsia, and low birth weight. Neuropsychological consequences in children include
cognitive disorders (attention deficits, memory impairments, and decreased academic
achievement), changes in mood, and behavior. Several cohort studies have shown an
association between vitamin B12 levels in the blood or maternal dietary intake and cognitive
outcomes in children. However, the majority of published studies on the negative impact of
low vitamin B12 levels on the cognitive status of children are observational in nature and
cannot confirm a causal relationship. The diagnosis of vitamin B12 deficiency is based on
clinical presentation, neurological and psychiatric findings, cognitive testing, and laboratory
diagnostics, which include circulating and functional biomarkers. Replenishment of
cobalamin deficiency is equally effective via parenteral and oral routes if adequate doses are
administered.
Conclusion: Vitamin B12 deficiency is relatively common among children and adolescents,
and it leads to neurological and psychiatric impairments that, if left untreated, can result in
irreversible changes.",
publisher = "Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju University of Belgrade – Faculty of Special Education and Rehabilitation",
journal = "Zbornik radova - 12. Međunarodni naučni skup Specijalna edukacija i rehabilitacija danas Beograd, 27–28. oktobar 2023. Godine",
title = "Status vitamina b12 i razvoj dece, Vitamin b12 status and development in children and adolescents",
pages = "587-581",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_5387"
}

Pavlović, D.,& Pavlović, A.. (2023). Status vitamina b12 i razvoj dece. in Zbornik radova - 12. Međunarodni naučni skup Specijalna edukacija i rehabilitacija danas Beograd, 27–28. oktobar 2023. Godine
Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju University of Belgrade – Faculty of Special Education and Rehabilitation., 581-587.
https://hdl.handle.net/21.15107/rcub_rfasper_5387

Pavlović D, Pavlović A. Status vitamina b12 i razvoj dece. in Zbornik radova - 12. Međunarodni naučni skup Specijalna edukacija i rehabilitacija danas Beograd, 27–28. oktobar 2023. Godine. 2023;:581-587.
https://hdl.handle.net/21.15107/rcub_rfasper_5387 .

Pavlović, Dragan, Pavlović, Aleksandra, "Status vitamina b12 i razvoj dece" in Zbornik radova - 12. Međunarodni naučni skup Specijalna edukacija i rehabilitacija danas Beograd, 27–28. oktobar 2023. Godine (2023):581-587,
https://hdl.handle.net/21.15107/rcub_rfasper_5387 .

TY  - JOUR
AU  - Djordjevic, Jelena
AU  - Arsić, Slađana
AU  - Pavlović, Dragan
AU  - Pavlović, Aleksandra
PY  - 2022
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/5021
AB  - Cognitive dysfunction has been recognized as a key aspect
of schizophrenia evident even during remission of symptoms.
During the previous decade, interest in cognitive deficits has
increased due to the recognition of their key importance for
the functional outcome and degree of social adaptation. Prominent cognitive deficits are disorders of memory, attention and
executive functions that manifest themselves as a disorder
of verbal fluency, problems with serial learning, difficulty in
problem solving, and disturbance of executive functions. The
observed cognitive deficit is attributed to the dysfunction of
cortical-cerebellar-thalamic circuits. Social cognition is the
ability to construct an image of relationships between oneself
and others and the ability to use flexible mental constructs as
a guide to social interactions. The data from previous studies
strongly support the association of neurocognitive and sociocognitive deficits with the performance of independent functioning and quality of life, emphasizing the need for prevention and treatment of cognitive deficits.
AB  - Kognitivna disfunkcija je prepoznata kao ključni aspekt šizofrenije, očigledan čak i tokom remisije simptoma.
Tokom prethodne decenije povećano je interesovanje za
kognitivne deficite zbog prepoznavanja njihovog ključnog
značaja za funkcionalni ishod i stepen socijalne adaptacije.
Izraženi kognitivni deficiti su poremećaji pamćenja, pažnje
i izvršnih funkcija koji se manifestuju kao poremećaj verbalne fluentnosti, problemi sa serijskim učenjem, teškoće
u rešavanju problema i poremećaj izvršnih funkcija.
Uočeni kognitivni deficit se pripisuje disfunkciji kortikalno
– cerebelarno - talamičkih kortikalnih kola. Socijalna kognicija je sposobnost da se konstruiše slika odnosa između
sebe i drugih i sposobnost korišćenja fleksibilnih mentalnih konstrukata kao vodiča za društvene interakcije. Podaci iz prethodnih studija snažno podržavaju povezanost
neurokognitivnih i sociokognitivnih deficita sa performansama samostalnog funkcionisanja i kvalitetom života,
naglašavajući potrebu za prevencijom i lečenjem kognitivnih deficita.
PB  - Akademija vaspitačko-medicinskih strukovnih studija,Kruševac; Zavod za javno zdravlje Ćuprija „Pomoravlje“ Ćuprija; Srpsko lekarsko društvo Podružnica Ćuprija; Društvo za neuronauke „Sozercanje iz Šumadije“, Kragujevac
T2  - PONS Medicinskog časopis
T1  - Cognitive aspects of schizophrenia / a narrative review
T1  - Kognitivni aspekti šizofrenije - narativni pregled
EP  - 25
IS  - 1
SP  - 19
VL  - 19
DO  - 10.5937/pomc19-37359
ER  - 

@article{
author = "Djordjevic, Jelena and Arsić, Slađana and Pavlović, Dragan and Pavlović, Aleksandra",
year = "2022",
abstract = "Cognitive dysfunction has been recognized as a key aspect
of schizophrenia evident even during remission of symptoms.
During the previous decade, interest in cognitive deficits has
increased due to the recognition of their key importance for
the functional outcome and degree of social adaptation. Prominent cognitive deficits are disorders of memory, attention and
executive functions that manifest themselves as a disorder
of verbal fluency, problems with serial learning, difficulty in
problem solving, and disturbance of executive functions. The
observed cognitive deficit is attributed to the dysfunction of
cortical-cerebellar-thalamic circuits. Social cognition is the
ability to construct an image of relationships between oneself
and others and the ability to use flexible mental constructs as
a guide to social interactions. The data from previous studies
strongly support the association of neurocognitive and sociocognitive deficits with the performance of independent functioning and quality of life, emphasizing the need for prevention and treatment of cognitive deficits., Kognitivna disfunkcija je prepoznata kao ključni aspekt šizofrenije, očigledan čak i tokom remisije simptoma.
Tokom prethodne decenije povećano je interesovanje za
kognitivne deficite zbog prepoznavanja njihovog ključnog
značaja za funkcionalni ishod i stepen socijalne adaptacije.
Izraženi kognitivni deficiti su poremećaji pamćenja, pažnje
i izvršnih funkcija koji se manifestuju kao poremećaj verbalne fluentnosti, problemi sa serijskim učenjem, teškoće
u rešavanju problema i poremećaj izvršnih funkcija.
Uočeni kognitivni deficit se pripisuje disfunkciji kortikalno
– cerebelarno - talamičkih kortikalnih kola. Socijalna kognicija je sposobnost da se konstruiše slika odnosa između
sebe i drugih i sposobnost korišćenja fleksibilnih mentalnih konstrukata kao vodiča za društvene interakcije. Podaci iz prethodnih studija snažno podržavaju povezanost
neurokognitivnih i sociokognitivnih deficita sa performansama samostalnog funkcionisanja i kvalitetom života,
naglašavajući potrebu za prevencijom i lečenjem kognitivnih deficita.",
publisher = "Akademija vaspitačko-medicinskih strukovnih studija,Kruševac; Zavod za javno zdravlje Ćuprija „Pomoravlje“ Ćuprija; Srpsko lekarsko društvo Podružnica Ćuprija; Društvo za neuronauke „Sozercanje iz Šumadije“, Kragujevac",
journal = "PONS Medicinskog časopis",
title = "Cognitive aspects of schizophrenia / a narrative review, Kognitivni aspekti šizofrenije - narativni pregled",
pages = "25-19",
number = "1",
volume = "19",
doi = "10.5937/pomc19-37359"
}

Djordjevic, J., Arsić, S., Pavlović, D.,& Pavlović, A.. (2022). Cognitive aspects of schizophrenia / a narrative review. in PONS Medicinskog časopis
Akademija vaspitačko-medicinskih strukovnih studija,Kruševac; Zavod za javno zdravlje Ćuprija „Pomoravlje“ Ćuprija; Srpsko lekarsko društvo Podružnica Ćuprija; Društvo za neuronauke „Sozercanje iz Šumadije“, Kragujevac., 19(1), 19-25.
https://doi.org/10.5937/pomc19-37359

Djordjevic J, Arsić S, Pavlović D, Pavlović A. Cognitive aspects of schizophrenia / a narrative review. in PONS Medicinskog časopis. 2022;19(1):19-25.
doi:10.5937/pomc19-37359 .

Djordjevic, Jelena, Arsić, Slađana, Pavlović, Dragan, Pavlović, Aleksandra, "Cognitive aspects of schizophrenia / a narrative review" in PONS Medicinskog časopis, 19, no. 1 (2022):19-25,
https://doi.org/10.5937/pomc19-37359 . .

TY  - JOUR
AU  - Jovanović, Stevan
AU  - Stojanović-Jovanović, Biljana
AU  - Pavlović, Aleksandra
AU  - Milošević, Radovan
AU  - Pavlović, Dragan
PY  - 2022
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/5023
AB  - Background/Aim. Aging entails a wide range of cognitive
processes that are not independent of one another. It leads
to changes in physical-motor characteristics and sometimes

to disability. The aim of this study was to examine the asso-
ciation between multiple cognitive performances in elderly

subjects and their physical-motor abilities. Method. The
study included 98 elderly participants (60+) (16 males and

82 females). Cognitive abilities were assessed by the Mon-
treal Cognitive Assessment (MoCA)/Serbian version, and

physical measures were assessed by the Senior Fitness Test
with its five subtests, supplemented by the Walking Speed
Test. Results. Several MoCA items demonstrated relatively
low variability, i.e., they proved to be too easy for most of

the participants. The participants exhibited the lowest per-
formance on the memory relating to other domains, fol-
lowed by executive functions, visuospatial skills, attention,

concentration, and working memory domains, with the

highest performance on temporal and spatial orientation re-
lating to other domains. Executive functions and language

correlated most significantly with physical strength. Agility
and dynamic balance, lower- and upper-body strength, and
aerobic endurance correlated moderately and positively.
Conclusion. This study underlines the positive correlation
between physical fitness and cognitive level in the elderly

and emphasizes the importance of physical fitness for cog-
nitive functions, especially those of executive type in elderly

subjects. Clinicians should consider the association between
cognitive function and physical-motor performances when
dealing with functioning improvement in the elderly. The

importance of designing the most efficient exercise pro-
grams to achieve maximal somatic and cognitive effects is

emphasized.
AB  - Uvod/Cilj. Proces starenja podrazumeva promene na širo-
kom spektru kognitivnih procesa koji nisu nezavisni jedni od

drugih. On, takođe, dovodi do promena u fizičko-motoričkim
karakteristikama, a ponekad i do invaliditeta. Cilj istraživanja

bio je da se ispita povezanost između više kognitivnih per-
formansi kod starijih ispitanika i njihovih fizičko-motoričkih

sposobnosti. Metode. U istraživanju je učestvovalo ukupno
98 starijih ispitanika (60+) (16 muškog i 82 ženskog pola).
Kognitivne sposobnosti procenjene su Montrealskom skalom

kognicije (Montreal Cognitive Assessment – MoCA)/srpska verzi-
ja, a mere fizičkih sposobnosti su procenjene Senior Fitness tes-
tom koji se sastoji od pet subtestova, dopunjenih testom

brzine hoda. Rezultati. Na nekoliko subtestova MoCA re-
zultati su ukazali na relativno malu varijabilnost, tj. pokazalo

se da su previše jednostavni za većinu ispitanika. Ispitanici su

pokazali najslabije rezultate u funkcionisanju memorije u od-
nosu na druge domene, a zatim slede izvršne funkcije, vizue-
lno prostorne veštine, pažnja, koncentracija i radna memorija,

sa najvišim performansama na vremenskoj i prostornoj ori-
jentaciji u odnosu na druge domene. Izvršne funkcije i jezik

su najznačajnije korelirali sa fizičkom snagom. Spretnost i
dinamična ravnoteža, snaga donjih i gornjih ekstremiteta i
aerobna izdržljivost su korelirali umereno i pozitivno.
Zaključak. Studija ukazuje na pozitivne korelacije između

fizičko-motoričkih sposobnosti i kognitivnog nivoa kod stari-
jih osoba i naglašava značaj fizičke spremnosti za kognitivno

funkcionisanje, a naročito u domenu izvršnih funkcija kod
njih. Kliničari bi trebalo da imaju u vidu povezanost između
kognitivnih funkcija i fizičko-motoričkih performansi, kada se
bave poboljšanjem funkcionisanja starijih osoba. Ukazuje se
na važnost dizajniranja najefikasnijih programa vežbanja za
postizanje maksimalnih somatskih i kognitivnih efekata.
PB  - Vojnomedicinska akademija
T2  - Vojnosanitetski pregled
T1  - Cognitive ability and motor performances in the elderly
T1  - Kognitivne sposobnosti i motoričke performanse starijih osoba
EP  - 474
IS  - 5
SP  - 465
VL  - 79
DO  - 10.2298/VSP200812143J
ER  - 

@article{
author = "Jovanović, Stevan and Stojanović-Jovanović, Biljana and Pavlović, Aleksandra and Milošević, Radovan and Pavlović, Dragan",
year = "2022",
abstract = "Background/Aim. Aging entails a wide range of cognitive
processes that are not independent of one another. It leads
to changes in physical-motor characteristics and sometimes

to disability. The aim of this study was to examine the asso-
ciation between multiple cognitive performances in elderly

subjects and their physical-motor abilities. Method. The
study included 98 elderly participants (60+) (16 males and

82 females). Cognitive abilities were assessed by the Mon-
treal Cognitive Assessment (MoCA)/Serbian version, and

physical measures were assessed by the Senior Fitness Test
with its five subtests, supplemented by the Walking Speed
Test. Results. Several MoCA items demonstrated relatively
low variability, i.e., they proved to be too easy for most of

the participants. The participants exhibited the lowest per-
formance on the memory relating to other domains, fol-
lowed by executive functions, visuospatial skills, attention,

concentration, and working memory domains, with the

highest performance on temporal and spatial orientation re-
lating to other domains. Executive functions and language

correlated most significantly with physical strength. Agility
and dynamic balance, lower- and upper-body strength, and
aerobic endurance correlated moderately and positively.
Conclusion. This study underlines the positive correlation
between physical fitness and cognitive level in the elderly

and emphasizes the importance of physical fitness for cog-
nitive functions, especially those of executive type in elderly

subjects. Clinicians should consider the association between
cognitive function and physical-motor performances when
dealing with functioning improvement in the elderly. The

importance of designing the most efficient exercise pro-
grams to achieve maximal somatic and cognitive effects is

emphasized., Uvod/Cilj. Proces starenja podrazumeva promene na širo-
kom spektru kognitivnih procesa koji nisu nezavisni jedni od

drugih. On, takođe, dovodi do promena u fizičko-motoričkim
karakteristikama, a ponekad i do invaliditeta. Cilj istraživanja

bio je da se ispita povezanost između više kognitivnih per-
formansi kod starijih ispitanika i njihovih fizičko-motoričkih

sposobnosti. Metode. U istraživanju je učestvovalo ukupno
98 starijih ispitanika (60+) (16 muškog i 82 ženskog pola).
Kognitivne sposobnosti procenjene su Montrealskom skalom

kognicije (Montreal Cognitive Assessment – MoCA)/srpska verzi-
ja, a mere fizičkih sposobnosti su procenjene Senior Fitness tes-
tom koji se sastoji od pet subtestova, dopunjenih testom

brzine hoda. Rezultati. Na nekoliko subtestova MoCA re-
zultati su ukazali na relativno malu varijabilnost, tj. pokazalo

se da su previše jednostavni za većinu ispitanika. Ispitanici su

pokazali najslabije rezultate u funkcionisanju memorije u od-
nosu na druge domene, a zatim slede izvršne funkcije, vizue-
lno prostorne veštine, pažnja, koncentracija i radna memorija,

sa najvišim performansama na vremenskoj i prostornoj ori-
jentaciji u odnosu na druge domene. Izvršne funkcije i jezik

su najznačajnije korelirali sa fizičkom snagom. Spretnost i
dinamična ravnoteža, snaga donjih i gornjih ekstremiteta i
aerobna izdržljivost su korelirali umereno i pozitivno.
Zaključak. Studija ukazuje na pozitivne korelacije između

fizičko-motoričkih sposobnosti i kognitivnog nivoa kod stari-
jih osoba i naglašava značaj fizičke spremnosti za kognitivno

funkcionisanje, a naročito u domenu izvršnih funkcija kod
njih. Kliničari bi trebalo da imaju u vidu povezanost između
kognitivnih funkcija i fizičko-motoričkih performansi, kada se
bave poboljšanjem funkcionisanja starijih osoba. Ukazuje se
na važnost dizajniranja najefikasnijih programa vežbanja za
postizanje maksimalnih somatskih i kognitivnih efekata.",
publisher = "Vojnomedicinska akademija",
journal = "Vojnosanitetski pregled",
title = "Cognitive ability and motor performances in the elderly, Kognitivne sposobnosti i motoričke performanse starijih osoba",
pages = "474-465",
number = "5",
volume = "79",
doi = "10.2298/VSP200812143J"
}

Jovanović, S., Stojanović-Jovanović, B., Pavlović, A., Milošević, R.,& Pavlović, D.. (2022). Cognitive ability and motor performances in the elderly. in Vojnosanitetski pregled
Vojnomedicinska akademija., 79(5), 465-474.
https://doi.org/10.2298/VSP200812143J

Jovanović S, Stojanović-Jovanović B, Pavlović A, Milošević R, Pavlović D. Cognitive ability and motor performances in the elderly. in Vojnosanitetski pregled. 2022;79(5):465-474.
doi:10.2298/VSP200812143J .

Jovanović, Stevan, Stojanović-Jovanović, Biljana, Pavlović, Aleksandra, Milošević, Radovan, Pavlović, Dragan, "Cognitive ability and motor performances in the elderly" in Vojnosanitetski pregled, 79, no. 5 (2022):465-474,
https://doi.org/10.2298/VSP200812143J . .

TY  - JOUR
AU  - Božić, Marija
AU  - Milenković, Marija
AU  - Pavlović, Dragan
AU  - Stamenković, Miroslav
AU  - Pavlović, Aleksandra
PY  - 2022
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/4569
AB  - Vitamin B1 (aneurin, thiamine) is a water-soluble vitamin necessary for the normal function of the nervous
system, visual system and heart and is part of important enzymes in the body. Thiamine enables the normal
use of glucose, other carbohydrates and proteins, and enables the supply of energy to the organism.
The main sources of thiamine are exogenous and small amounts are synthesized by microorganisms of
the human intestinal microbiome.
Vitamin B1 cannot accumulate in the body, so signs of deficiency are quickly manifested. Hypovitaminosis
B1 is seen in chronic ethyl abuse, persistent vomiting (as in some pregnant women) or after bariatric
surgical procedures, but in a mild form it is present in the general population.
Normal daily needs for vitamin B1 depend on calorie intake, and 0.4 mg should be ingested for every
1000 kcal.
AB  - Vitamin B1 (aneurin, tiamin) rastvorljiv je u vodi, neopho-
dan je za normalno funkcionisanje nervnog sistema, organa
vida i srca i deo je važnih enzima u telu. Tiamin omogućava
normalnu upotrebu glukoze, drugih ugljenih hidrata i pro-
teina i snabdevanje organizma energijom.
Glavni izvori tiamina su egzogeni i male količine sinte-
tišu mikroorganizmi ljudskog crevnog mikrobioma.
Vitamin B1 se ne može nakupljati u telu, pa se znakovi ne-
dostatka brzo manifestuju. Hipovitaminoza B1 se opaža
kod hronične zloupotrebe alkohola, upornog povraćanja
(kao kod nekih trudnica) ili posle barijatrijskih hirur-
ških procedura, ali u blagom obliku je prisutna i u opštoj
populaciji.
Normalne dnevne potrebe za vitaminom B1 zavise od unosa
kalorija, pa na svakih 1000 kcal treba unetiti 0,4 mg ovog
vitamina.
PB  - Serbian Medical Society
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Vitamin B1, eye and brain
T1  - Vitamin B1, oko i mozak
IS  - 3-4
SP  - 233
VL  - 150
VL  - 237
DO  - 10.2298/SARH210929019B
ER  - 

@article{
author = "Božić, Marija and Milenković, Marija and Pavlović, Dragan and Stamenković, Miroslav and Pavlović, Aleksandra",
year = "2022",
abstract = "Vitamin B1 (aneurin, thiamine) is a water-soluble vitamin necessary for the normal function of the nervous
system, visual system and heart and is part of important enzymes in the body. Thiamine enables the normal
use of glucose, other carbohydrates and proteins, and enables the supply of energy to the organism.
The main sources of thiamine are exogenous and small amounts are synthesized by microorganisms of
the human intestinal microbiome.
Vitamin B1 cannot accumulate in the body, so signs of deficiency are quickly manifested. Hypovitaminosis
B1 is seen in chronic ethyl abuse, persistent vomiting (as in some pregnant women) or after bariatric
surgical procedures, but in a mild form it is present in the general population.
Normal daily needs for vitamin B1 depend on calorie intake, and 0.4 mg should be ingested for every
1000 kcal., Vitamin B1 (aneurin, tiamin) rastvorljiv je u vodi, neopho-
dan je za normalno funkcionisanje nervnog sistema, organa
vida i srca i deo je važnih enzima u telu. Tiamin omogućava
normalnu upotrebu glukoze, drugih ugljenih hidrata i pro-
teina i snabdevanje organizma energijom.
Glavni izvori tiamina su egzogeni i male količine sinte-
tišu mikroorganizmi ljudskog crevnog mikrobioma.
Vitamin B1 se ne može nakupljati u telu, pa se znakovi ne-
dostatka brzo manifestuju. Hipovitaminoza B1 se opaža
kod hronične zloupotrebe alkohola, upornog povraćanja
(kao kod nekih trudnica) ili posle barijatrijskih hirur-
ških procedura, ali u blagom obliku je prisutna i u opštoj
populaciji.
Normalne dnevne potrebe za vitaminom B1 zavise od unosa
kalorija, pa na svakih 1000 kcal treba unetiti 0,4 mg ovog
vitamina.",
publisher = "Serbian Medical Society",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Vitamin B1, eye and brain, Vitamin B1, oko i mozak",
number = "3-4",
pages = "233",
volume = "150, 237",
doi = "10.2298/SARH210929019B"
}

Božić, M., Milenković, M., Pavlović, D., Stamenković, M.,& Pavlović, A.. (2022). Vitamin B1, eye and brain. in Srpski arhiv za celokupno lekarstvo
Serbian Medical Society., 150(3-4), 233.
https://doi.org/10.2298/SARH210929019B

Božić M, Milenković M, Pavlović D, Stamenković M, Pavlović A. Vitamin B1, eye and brain. in Srpski arhiv za celokupno lekarstvo. 2022;150(3-4):233.
doi:10.2298/SARH210929019B .

Božić, Marija, Milenković, Marija, Pavlović, Dragan, Stamenković, Miroslav, Pavlović, Aleksandra, "Vitamin B1, eye and brain" in Srpski arhiv za celokupno lekarstvo, 150, no. 3-4 (2022):233,
https://doi.org/10.2298/SARH210929019B . .

TY  - CONF
AU  - Pavlović, Dragan
AU  - Pavlović, Aleksandra
PY  - 2022
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/4966
AB  - Poremećaj pažnje sa hiperaktivnošću (eng. attention deficit/hyperactivity disorder ADHD) je multifaktorski poremećaj čija učestalost iznosi 5–7% kod dece i oko 2,5% kod odraslih. Smatra se da je moguće postojanje tri slična ali po- sebna tipa poremećaja. Posebno se izdvaja ADHD sa početkom u odraslom dobu.
Procenjuje se da su nasledni faktori prisutni kod otprilike 77% slučajeva ADHD-a, pri čemu je identifikovano 18 različitih gena, međutim, spoljašni faktori igraju značajnu ulogu u ekspresiji simptoma. Postoji više modela moždane disfunkcije u ADHD kao što su prefrontalno-egzekutivni model, model pažnje, model nagrade, poremećaj neuronske mreže mirovanja, model kognicije i energije i neurorazvojni model. Biohemijske promene su višestruke i uključuju dopaminergički, adrenergički, serotonergički i holinergički si- stem. Ispitivanja strukture mozga su pokazala smanjenu zapreminu mozga kod dece sa ADHD, a posebno prefrontalne kore, prednje cingularne kore, bazalnih ganglija i malog mozga, a donekle i temporalnog i parijetalnog režnja. Postoje individualne varijacije u međusobnom odnosu kortikalne i supkortikalne disfunkcije što dovodi do heterogenog kliničkog ispoljavanja. S obzirom na nedovoljnu efikasnost i značajne neželjene efekte upotrebe psihostimulan- sa u lečenju ADHD, primena mikronutrijenata je moguća terapija bez značajnih neželjenih pojava i to pre svega cinka, omega-3 masnih kiselina i vitamina D, kao i multivitamina-multiminerala.
AB  - Attention deficit/hyperactivity disorder (ADHD) is a multifactorial disorder diagnosed in 5-7% children and 2,5% of adults in general population. Three similar but distinct subtypes of ADHD has been identified. A separate form is ADHD with adult onset. Hereditary factors are explaining 77% of cases with at least 18 different susceptibility genes identified, each one with small effect size. However, the inlfuence of several envorinmental factors have been recognized. There are several models of brain dysfunction in ADHD, comprising prefrontal-executive model, attention model, reward model, disruption of neuronal default-mode network, cognition and energy model and neurodevelopmental model.
There are multiple biochemical alterations in ADHD, including dopaminergic, adrenergic, serotonergic and cholinergic system.
Current research indicate reduced brain volume in children with ADHD, particularly in prefrontal cortex, anterior cingulate cortex, basal ganglia and cerebellum, but also in temporal and parietal lobe to a certain extent. The extent of cortical and subcortical brain involvement varies between individuals which leads to wide variety of clinical presentation. Considering reduced efficacy and significant side effects of psychostimulants in ADHD treatment, the use of micronutrients is a potential therapeutical approach without significant side effects. Most o evidence is available to the use of zinc, omega-3 fat acids and vitamin D, as well as for multivitamins and minerals.
PB  - Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju (ICF)
C3  - Zbornik radova - Nacionalni naučni skup " obrazovanje i rehabilitacija odraslih osoba sa smetnjama u razvoju i problemima u ponašanju ", Beograd, Srbija, 21. decembar 2022. godine
T1  - Poremećaj pažnje sa hiperaktivnošću – savremeni pregled neurobioloških osnova
T1  - An update on neurobiology of attention deficit hyperactivity disorder
EP  - 209
SP  - 201
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_4966
ER  - 

@conference{
author = "Pavlović, Dragan and Pavlović, Aleksandra",
year = "2022",
abstract = "Poremećaj pažnje sa hiperaktivnošću (eng. attention deficit/hyperactivity disorder ADHD) je multifaktorski poremećaj čija učestalost iznosi 5–7% kod dece i oko 2,5% kod odraslih. Smatra se da je moguće postojanje tri slična ali po- sebna tipa poremećaja. Posebno se izdvaja ADHD sa početkom u odraslom dobu.
Procenjuje se da su nasledni faktori prisutni kod otprilike 77% slučajeva ADHD-a, pri čemu je identifikovano 18 različitih gena, međutim, spoljašni faktori igraju značajnu ulogu u ekspresiji simptoma. Postoji više modela moždane disfunkcije u ADHD kao što su prefrontalno-egzekutivni model, model pažnje, model nagrade, poremećaj neuronske mreže mirovanja, model kognicije i energije i neurorazvojni model. Biohemijske promene su višestruke i uključuju dopaminergički, adrenergički, serotonergički i holinergički si- stem. Ispitivanja strukture mozga su pokazala smanjenu zapreminu mozga kod dece sa ADHD, a posebno prefrontalne kore, prednje cingularne kore, bazalnih ganglija i malog mozga, a donekle i temporalnog i parijetalnog režnja. Postoje individualne varijacije u međusobnom odnosu kortikalne i supkortikalne disfunkcije što dovodi do heterogenog kliničkog ispoljavanja. S obzirom na nedovoljnu efikasnost i značajne neželjene efekte upotrebe psihostimulan- sa u lečenju ADHD, primena mikronutrijenata je moguća terapija bez značajnih neželjenih pojava i to pre svega cinka, omega-3 masnih kiselina i vitamina D, kao i multivitamina-multiminerala., Attention deficit/hyperactivity disorder (ADHD) is a multifactorial disorder diagnosed in 5-7% children and 2,5% of adults in general population. Three similar but distinct subtypes of ADHD has been identified. A separate form is ADHD with adult onset. Hereditary factors are explaining 77% of cases with at least 18 different susceptibility genes identified, each one with small effect size. However, the inlfuence of several envorinmental factors have been recognized. There are several models of brain dysfunction in ADHD, comprising prefrontal-executive model, attention model, reward model, disruption of neuronal default-mode network, cognition and energy model and neurodevelopmental model.
There are multiple biochemical alterations in ADHD, including dopaminergic, adrenergic, serotonergic and cholinergic system.
Current research indicate reduced brain volume in children with ADHD, particularly in prefrontal cortex, anterior cingulate cortex, basal ganglia and cerebellum, but also in temporal and parietal lobe to a certain extent. The extent of cortical and subcortical brain involvement varies between individuals which leads to wide variety of clinical presentation. Considering reduced efficacy and significant side effects of psychostimulants in ADHD treatment, the use of micronutrients is a potential therapeutical approach without significant side effects. Most o evidence is available to the use of zinc, omega-3 fat acids and vitamin D, as well as for multivitamins and minerals.",
publisher = "Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju (ICF)",
journal = "Zbornik radova - Nacionalni naučni skup " obrazovanje i rehabilitacija odraslih osoba sa smetnjama u razvoju i problemima u ponašanju ", Beograd, Srbija, 21. decembar 2022. godine",
title = "Poremećaj pažnje sa hiperaktivnošću – savremeni pregled neurobioloških osnova, An update on neurobiology of attention deficit hyperactivity disorder",
pages = "209-201",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_4966"
}

Pavlović, D.,& Pavlović, A.. (2022). Poremećaj pažnje sa hiperaktivnošću – savremeni pregled neurobioloških osnova. in Zbornik radova - Nacionalni naučni skup " obrazovanje i rehabilitacija odraslih osoba sa smetnjama u razvoju i problemima u ponašanju ", Beograd, Srbija, 21. decembar 2022. godine
Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju (ICF)., 201-209.
https://hdl.handle.net/21.15107/rcub_rfasper_4966

Pavlović D, Pavlović A. Poremećaj pažnje sa hiperaktivnošću – savremeni pregled neurobioloških osnova. in Zbornik radova - Nacionalni naučni skup " obrazovanje i rehabilitacija odraslih osoba sa smetnjama u razvoju i problemima u ponašanju ", Beograd, Srbija, 21. decembar 2022. godine. 2022;:201-209.
https://hdl.handle.net/21.15107/rcub_rfasper_4966 .

Pavlović, Dragan, Pavlović, Aleksandra, "Poremećaj pažnje sa hiperaktivnošću – savremeni pregled neurobioloških osnova" in Zbornik radova - Nacionalni naučni skup " obrazovanje i rehabilitacija odraslih osoba sa smetnjama u razvoju i problemima u ponašanju ", Beograd, Srbija, 21. decembar 2022. godine (2022):201-209,
https://hdl.handle.net/21.15107/rcub_rfasper_4966 .

TY  - CONF
AU  - Pavlović, Aleksandra
AU  - Milenković, Marija
AU  - Stevanović, Aleksandar
AU  - Pavlović, Dragan
PY  - 2021
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/3689
AB  - Uvod: Iako je SARS-CoV-2 respiratorna infekcija, virus je neurotropan i 40% bolesnika ima neurološke manifestacije. Česta pojava slučajeva sa produženim smetnjama posle COVID-19 nametnula je uvođenje sindroma „dugog COVID-a”, koji označava set različitih simptoma koji perzistiraju minimum četiri nedelje nakon akutne infekcije. Jedna od vodećih manifestacija je kognitivni pad.
Cilj: Analiza učestalosti i neuropsihološkog profila kognitivnog pada u „dugom COVID-u”.
Metod: Pregled literature.
Rezultati: Među CNS posledicama „dugog COVID-a” najčešće se registruju kognitivni pad, glavobolja, izmene sna i vrtoglavica. Kognitivne izmene bolesnici opisuju kao doživljaj postojanja „magle u glavi”, a podrazumeva pad koncentracije ili smetnje kratkoročnog pamćenja, koji može da utiče na povratak uobičajenom socijalnom i profesionalnom funkcionisanju. Neurokognitivne komplikacije akutne SARS-CoV-2 infekcije se opisuju naročito kod kritično obolelih i respiratorno ugroženih bolesnika i porede sa sličnim sindromima posle sepse ili boravka u jedinicama intenzivnog lečenja („post-ICU syndrome“). Međutim, bar 20% bolesnika sa blagim formama COVID-19 koje nisu zahtevale hospitalizaciju takođe ima produžene kognitivne smetnje. Fenomeni u sklopu „brain fog“ slični su onima kod osoba sa sindromom hroničnog umora. Infekcija SARS-Cov-2 virusom bilo kog stepena težine povećava rizik za nastanak kognitivnog pada. Do sada nije istražen uticaj kognitivnog pada nakon COVID-19 na kvalitet života i aktivnosti svakodnevnog življenja, kao i uticaj psiholoških i socijalnih aspekata pandemije na kogniciju. Mogući mehanizmi kognitivne disfukcije su: direktna infekcija CNS-a, udaljeni efekti sistemske infekcije („citokinska oluja” i dr.), vaskularno oštećenje mozga, neuroinflamacija, autoimuni odgovor protiv CNS-a, hipometabolizam limbičkog sistema i orbitofrontalnog korteksa, kao i neurodegeneracija slična onoj u Alchajmerovoj bolesti, pri čemu je moguće da se neki od ovih mehanizama prepliću.
Zaključak: Kognitive manifestacije „dugog COVID-a” nisu retke i značajno utiču na povratak u uobičajeni lični i profesionalni milje preživelih. Neophodno je dugoročno praćenje ovih bolesnika i sagledavanje različitih etioloških i terapijskih aspekata kognitivnih izmena u okviru „dugog COVID-a”.
AB  - Introduction: Although SARS-CoV-2 is a respiratory infection, the virus is neurotropic and neurological manifestations are seen in 40% patients. Recognition of prolonged post-COVID symptoms led to the introduction of the term “long COVID syndrome”, referring to a set of various symptoms persisting for a minimum of four weeks after acute infection. One of the main manifestations is cognitive decline.
Aim: Analysis of incidence and neuropsychological profile of cognitive decline in “long COVID” syndrome.
Method: Literature review.
Results: Most frequent CNS manifestations of “long COVID” include cognitive decline, headache, sleep disturbance, and dizziness. Cognitive changes are reported as “brain fog” and correspond to a decline in attention and short-term memory, impacting return to premorbid social and professional activities. Acute SARS-CoV-2 neurocognitive complications are seen particularly in critically ill and respiratory insufficient patients, comparable to the similar phenomenon of post-sepsis and intensive care unit treatment (“post-ICU syndrome”). However, 20% of patients with mild COVID-19, not requiring hospitalization, also reported prolonged cognitive complaints, resembling those in patients with chronic fatigue syndrome. SARS-Cov-2 infection of any severity increases the risk for cognitive decline. The impact of post-COVID cognitive decline on the quality of life and activities of daily living as well as the influence of psychological and social aspects of the pandemic on cognition remain to be investigated. Potential mechanisms of cognitive dysfunction are direct CNS infection, remote effects of systemic infection (“cytokine storm” etc.), vascular brain damage, neuroinflammation, autoimmune response directed to the CNS components, hypometabolism in the limbic and orbitofrontal cortex, as well as neurodegeneration comparable to those in Alzheimer’s disease. Several different mechanisms may also be intertwined.
Conclusion: Cognitive manifestations of “long COVID” are not rare and have a significant influence on personal and professional activities of the survivors. Long-term follow-up and analysis of various etiological and therapeutic aspects of cognitive changes within “long-COVID” are needed.
PB  - Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation
C3  - Zbornik rezimea – 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021
T1  - Neurokognitivni sindrom „dugog covid-a”: pregled literature
T1  - Neurocognitive syndrome of “long covid”: literature review
EP  - 90
SP  - 89
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_3689
ER  - 

@conference{
author = "Pavlović, Aleksandra and Milenković, Marija and Stevanović, Aleksandar and Pavlović, Dragan",
year = "2021",
abstract = "Uvod: Iako je SARS-CoV-2 respiratorna infekcija, virus je neurotropan i 40% bolesnika ima neurološke manifestacije. Česta pojava slučajeva sa produženim smetnjama posle COVID-19 nametnula je uvođenje sindroma „dugog COVID-a”, koji označava set različitih simptoma koji perzistiraju minimum četiri nedelje nakon akutne infekcije. Jedna od vodećih manifestacija je kognitivni pad.
Cilj: Analiza učestalosti i neuropsihološkog profila kognitivnog pada u „dugom COVID-u”.
Metod: Pregled literature.
Rezultati: Među CNS posledicama „dugog COVID-a” najčešće se registruju kognitivni pad, glavobolja, izmene sna i vrtoglavica. Kognitivne izmene bolesnici opisuju kao doživljaj postojanja „magle u glavi”, a podrazumeva pad koncentracije ili smetnje kratkoročnog pamćenja, koji može da utiče na povratak uobičajenom socijalnom i profesionalnom funkcionisanju. Neurokognitivne komplikacije akutne SARS-CoV-2 infekcije se opisuju naročito kod kritično obolelih i respiratorno ugroženih bolesnika i porede sa sličnim sindromima posle sepse ili boravka u jedinicama intenzivnog lečenja („post-ICU syndrome“). Međutim, bar 20% bolesnika sa blagim formama COVID-19 koje nisu zahtevale hospitalizaciju takođe ima produžene kognitivne smetnje. Fenomeni u sklopu „brain fog“ slični su onima kod osoba sa sindromom hroničnog umora. Infekcija SARS-Cov-2 virusom bilo kog stepena težine povećava rizik za nastanak kognitivnog pada. Do sada nije istražen uticaj kognitivnog pada nakon COVID-19 na kvalitet života i aktivnosti svakodnevnog življenja, kao i uticaj psiholoških i socijalnih aspekata pandemije na kogniciju. Mogući mehanizmi kognitivne disfukcije su: direktna infekcija CNS-a, udaljeni efekti sistemske infekcije („citokinska oluja” i dr.), vaskularno oštećenje mozga, neuroinflamacija, autoimuni odgovor protiv CNS-a, hipometabolizam limbičkog sistema i orbitofrontalnog korteksa, kao i neurodegeneracija slična onoj u Alchajmerovoj bolesti, pri čemu je moguće da se neki od ovih mehanizama prepliću.
Zaključak: Kognitive manifestacije „dugog COVID-a” nisu retke i značajno utiču na povratak u uobičajeni lični i profesionalni milje preživelih. Neophodno je dugoročno praćenje ovih bolesnika i sagledavanje različitih etioloških i terapijskih aspekata kognitivnih izmena u okviru „dugog COVID-a”., Introduction: Although SARS-CoV-2 is a respiratory infection, the virus is neurotropic and neurological manifestations are seen in 40% patients. Recognition of prolonged post-COVID symptoms led to the introduction of the term “long COVID syndrome”, referring to a set of various symptoms persisting for a minimum of four weeks after acute infection. One of the main manifestations is cognitive decline.
Aim: Analysis of incidence and neuropsychological profile of cognitive decline in “long COVID” syndrome.
Method: Literature review.
Results: Most frequent CNS manifestations of “long COVID” include cognitive decline, headache, sleep disturbance, and dizziness. Cognitive changes are reported as “brain fog” and correspond to a decline in attention and short-term memory, impacting return to premorbid social and professional activities. Acute SARS-CoV-2 neurocognitive complications are seen particularly in critically ill and respiratory insufficient patients, comparable to the similar phenomenon of post-sepsis and intensive care unit treatment (“post-ICU syndrome”). However, 20% of patients with mild COVID-19, not requiring hospitalization, also reported prolonged cognitive complaints, resembling those in patients with chronic fatigue syndrome. SARS-Cov-2 infection of any severity increases the risk for cognitive decline. The impact of post-COVID cognitive decline on the quality of life and activities of daily living as well as the influence of psychological and social aspects of the pandemic on cognition remain to be investigated. Potential mechanisms of cognitive dysfunction are direct CNS infection, remote effects of systemic infection (“cytokine storm” etc.), vascular brain damage, neuroinflammation, autoimmune response directed to the CNS components, hypometabolism in the limbic and orbitofrontal cortex, as well as neurodegeneration comparable to those in Alzheimer’s disease. Several different mechanisms may also be intertwined.
Conclusion: Cognitive manifestations of “long COVID” are not rare and have a significant influence on personal and professional activities of the survivors. Long-term follow-up and analysis of various etiological and therapeutic aspects of cognitive changes within “long-COVID” are needed.",
publisher = "Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation",
journal = "Zbornik rezimea – 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021",
title = "Neurokognitivni sindrom „dugog covid-a”: pregled literature, Neurocognitive syndrome of “long covid”: literature review",
pages = "90-89",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_3689"
}

Pavlović, A., Milenković, M., Stevanović, A.,& Pavlović, D.. (2021). Neurokognitivni sindrom „dugog covid-a”: pregled literature. in Zbornik rezimea – 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021
Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation., 89-90.
https://hdl.handle.net/21.15107/rcub_rfasper_3689

Pavlović A, Milenković M, Stevanović A, Pavlović D. Neurokognitivni sindrom „dugog covid-a”: pregled literature. in Zbornik rezimea – 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021. 2021;:89-90.
https://hdl.handle.net/21.15107/rcub_rfasper_3689 .

Pavlović, Aleksandra, Milenković, Marija, Stevanović, Aleksandar, Pavlović, Dragan, "Neurokognitivni sindrom „dugog covid-a”: pregled literature" in Zbornik rezimea – 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021 (2021):89-90,
https://hdl.handle.net/21.15107/rcub_rfasper_3689 .

TY  - CONF
AU  - Pavlović, Dragan
AU  - Pavlović, Aleksandra
AU  - Milenković, Marija
PY  - 2021
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/3784
AB  - Uvod: Cink je drugi najzastuplјeniji esencijalni metal u organizmu i jedini koji je prisutan u svim klasama enzima. Cink se resorbuje u tankom crevu. Nema depoa cinka u organizmu. On se izlučuje putem bubrega, kože i creva. Hrana životinjsкog porekla ima manje cinka ali nema fitata pa je dobar izvor cinka.
Cilј: Cilј rada je da se pregledom relevantne literature izdvoje istraživanja koja potvrđuju značaj cinka u radu mozga i razvoju dece.
Metod: Izvršeno je pretraživanje baze podataka Pub Med korišćenjem klјučnih reči cink, mozak, kognicija, deca.
Rezultati: Cink je neophodan za funkcionisanje centralnog nervnog sistema, učestvuje u neurotransmisiji, posebno u hipokampusu gde reguliše glutamate i gamaaminobuternu kiselinu koji su najzastuplјeniji neurotransmiteri u moz- gu. Ovim se omogućuju normalne kognitivne funkcije. Osim u prenosu infor- macija, cink u mozgu omogućava i metabolizam DNK, rast moždanog tubulina i fosforilaciju. Cink stabilizuje ćelijske membrane i druge ćelijske komponente i bitan je za transkripciju polinukleotida u procesu genetske ekspresije. Cink omogućava deobu, rast i diferencijaciju ćelija, što je bitno za intrauterini ra- zvoj ploda, stimuliše rast i razvoj organizma, a važan je i za čulo ukusa i mi- risa. Cink je kritičan za rast i razvoj mozga, u sintezi DNK, RNK i proteina, pa nedostatak cinka u intrauterinom periodu može da dovede do malformacija mozga, a kod dece do sporijeg i slabijeg razvoja. Smatra se da kao posledi- ca nedostatka cinka u svetu godišnje umre oko 800.000 dece. Manjak cinka dovodi do usporenja rasta i razvoja kod dece, usporenja seksualnog razvoja, gubitka apetita, poremećaja imuniteta, dijareje, muškog hipogonadizma, in- fertiliteta i oštećenja oka.
Zaklјučak: Cink je klјučan mikronutrijent za rad neurona i veoma je bitan u normalnom razvoju dece. Balans cinka je neophodno postići tokom celog živo- ta čoveka kako bi se omogućio normalan razvoj i kognicija.
AB  - Introduction: Zinc is the second most abundant essential metal in the body and the only one present in all classes of enzymes. Zinc is absorbed in the small intestine. There is no zinc depot in the body. It is excreted through the kidneys, skin and intestines. Foods of animal origin have less zinc but no phytate so they are a good source of zinc. 
Aim: The aim of this paper is to examine the importance of zinc in brain function and child development.
Method: The Pub Med database was searched using the keywords zinc, brain, cognition, children.
Results: Zinc is necessary for the functioning of the central nervous system, it participates in neurotransmission, especially in the hippocampus, where it regulates glutamate and gamma-aminobutyric acid, which are the most common neurotransmitters in the brain. This allows for normal cognitive functions. In addition to transmitting information, zinc in the brain also enables DNA metabolism, brain tubulin growth and phosphorylation.
Zinc stabilizes cell membranes and other cell components and is essential for the transcription of polynucleotides in the process of genetic expression. Zinc balance disorder occurs in Alzheimer’s disease, depression, etc. Zinc enables cell division, growth and differentiation, which is important for the intrauterine development of the fetus, stimulates the growth and development of the organism, and is also important for the sense of taste and smell. Zinc is critical for the growth and development of the brain, in the synthesis of DNA, RNA and proteins, so the lack of zinc in the intrauterine period can lead to brain malformations, and in children to slower and weaker development. It is estimated that around 800,000 children die each year as a result of zinc deficiency in the world. Zinc deficiency leads to growth retardation and development in children, slowing of sexual development, loss of appetite, immune disorders, diarrhea, male hypogonadism, infertility and eye damage.
Conclusion: Zinc is a key micronutrient for the work of neurons and is very important in the normal development of children. Zinc balance is necessary to be achieved throughout a person’s life in order to enable normal development and cognition.
PB  - Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation
C3  - Zbornik radova - 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.
T1  - Značaj cinka u radu mozga i razvoju dece – narativni prikaz
T1  - The importance of zinc in brain function and child development – a narrative review
EP  - 267
SP  - 259
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_3784
ER  - 

@conference{
author = "Pavlović, Dragan and Pavlović, Aleksandra and Milenković, Marija",
year = "2021",
abstract = "Uvod: Cink je drugi najzastuplјeniji esencijalni metal u organizmu i jedini koji je prisutan u svim klasama enzima. Cink se resorbuje u tankom crevu. Nema depoa cinka u organizmu. On se izlučuje putem bubrega, kože i creva. Hrana životinjsкog porekla ima manje cinka ali nema fitata pa je dobar izvor cinka.
Cilј: Cilј rada je da se pregledom relevantne literature izdvoje istraživanja koja potvrđuju značaj cinka u radu mozga i razvoju dece.
Metod: Izvršeno je pretraživanje baze podataka Pub Med korišćenjem klјučnih reči cink, mozak, kognicija, deca.
Rezultati: Cink je neophodan za funkcionisanje centralnog nervnog sistema, učestvuje u neurotransmisiji, posebno u hipokampusu gde reguliše glutamate i gamaaminobuternu kiselinu koji su najzastuplјeniji neurotransmiteri u moz- gu. Ovim se omogućuju normalne kognitivne funkcije. Osim u prenosu infor- macija, cink u mozgu omogućava i metabolizam DNK, rast moždanog tubulina i fosforilaciju. Cink stabilizuje ćelijske membrane i druge ćelijske komponente i bitan je za transkripciju polinukleotida u procesu genetske ekspresije. Cink omogućava deobu, rast i diferencijaciju ćelija, što je bitno za intrauterini ra- zvoj ploda, stimuliše rast i razvoj organizma, a važan je i za čulo ukusa i mi- risa. Cink je kritičan za rast i razvoj mozga, u sintezi DNK, RNK i proteina, pa nedostatak cinka u intrauterinom periodu može da dovede do malformacija mozga, a kod dece do sporijeg i slabijeg razvoja. Smatra se da kao posledi- ca nedostatka cinka u svetu godišnje umre oko 800.000 dece. Manjak cinka dovodi do usporenja rasta i razvoja kod dece, usporenja seksualnog razvoja, gubitka apetita, poremećaja imuniteta, dijareje, muškog hipogonadizma, in- fertiliteta i oštećenja oka.
Zaklјučak: Cink je klјučan mikronutrijent za rad neurona i veoma je bitan u normalnom razvoju dece. Balans cinka je neophodno postići tokom celog živo- ta čoveka kako bi se omogućio normalan razvoj i kognicija., Introduction: Zinc is the second most abundant essential metal in the body and the only one present in all classes of enzymes. Zinc is absorbed in the small intestine. There is no zinc depot in the body. It is excreted through the kidneys, skin and intestines. Foods of animal origin have less zinc but no phytate so they are a good source of zinc. 
Aim: The aim of this paper is to examine the importance of zinc in brain function and child development.
Method: The Pub Med database was searched using the keywords zinc, brain, cognition, children.
Results: Zinc is necessary for the functioning of the central nervous system, it participates in neurotransmission, especially in the hippocampus, where it regulates glutamate and gamma-aminobutyric acid, which are the most common neurotransmitters in the brain. This allows for normal cognitive functions. In addition to transmitting information, zinc in the brain also enables DNA metabolism, brain tubulin growth and phosphorylation.
Zinc stabilizes cell membranes and other cell components and is essential for the transcription of polynucleotides in the process of genetic expression. Zinc balance disorder occurs in Alzheimer’s disease, depression, etc. Zinc enables cell division, growth and differentiation, which is important for the intrauterine development of the fetus, stimulates the growth and development of the organism, and is also important for the sense of taste and smell. Zinc is critical for the growth and development of the brain, in the synthesis of DNA, RNA and proteins, so the lack of zinc in the intrauterine period can lead to brain malformations, and in children to slower and weaker development. It is estimated that around 800,000 children die each year as a result of zinc deficiency in the world. Zinc deficiency leads to growth retardation and development in children, slowing of sexual development, loss of appetite, immune disorders, diarrhea, male hypogonadism, infertility and eye damage.
Conclusion: Zinc is a key micronutrient for the work of neurons and is very important in the normal development of children. Zinc balance is necessary to be achieved throughout a person’s life in order to enable normal development and cognition.",
publisher = "Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation",
journal = "Zbornik radova - 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.",
title = "Značaj cinka u radu mozga i razvoju dece – narativni prikaz, The importance of zinc in brain function and child development – a narrative review",
pages = "267-259",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_3784"
}

Pavlović, D., Pavlović, A.,& Milenković, M.. (2021). Značaj cinka u radu mozga i razvoju dece – narativni prikaz. in Zbornik radova - 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.
Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation., 259-267.
https://hdl.handle.net/21.15107/rcub_rfasper_3784

Pavlović D, Pavlović A, Milenković M. Značaj cinka u radu mozga i razvoju dece – narativni prikaz. in Zbornik radova - 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.. 2021;:259-267.
https://hdl.handle.net/21.15107/rcub_rfasper_3784 .

Pavlović, Dragan, Pavlović, Aleksandra, Milenković, Marija, "Značaj cinka u radu mozga i razvoju dece – narativni prikaz" in Zbornik radova - 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021. (2021):259-267,
https://hdl.handle.net/21.15107/rcub_rfasper_3784 .

TY  - CONF
AU  - Pavlović, Aleksandra
AU  - Milenković, Marija
AU  - Stevanović, Aleksandar
AU  - Pavlović, Dragan
PY  - 2021
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/3776
AB  - Uvod: Iako je SARS-CoV-2 respiratorna infekcija, virus je neurotropan i 40% bolesnika ima neurološke manifestacije. Česta pojava slučajeva sa produženim smetnjama posle COVID-19 nametnula je uvođenje sindroma „dugog COVID-a“, koji označava set različitih simptoma koji perzistiraju minimum četiri nedelje nakon akutne infekcije. Jedna od vodećih manifestacija je kognitivni pad.
Cilj: Analiza učestalosti i neuropsihološkog profila kognitivnog pada u „dugom COVID-u“.
Metod: Pregled literature.
Rezultati: Među CNS posledicama „dugog COVID-a“ najčešće se registruju ko- gnitivni pad, glavobolja, izmene sna i vrtoglavica. Kognitivne izmene bolesnici opisuju kao doživljaj postojanja „magle u glavi“, a podrazumeva pad koncen- tracije ili smetnje kratkoročnog pamćenja, koji može da utiče na povratak uo- bičajenom socijalnom i profesionalnom funkcionisanju. Neurokognitivne kom- plikacije akutne SARS-CoV-2 infekcije se opisuju naročito kod kritično obolelih i respiratorno ugroženih bolesnika i porede sa sličnim sindromima posle sepse ili boravka u jedinicama intenzivnog lečenja (“post-ICU syndrome“). Međutim, bar 20% bolesnika sa blagim formama COVID-19 koje nisu zahtevale hospita- lizaciju takođe ima produžene kognitivne smetnje. Fenomeni u sklopu „bra- in fog“ slični su onima kod osoba sa sindromom hroničnog umora. Infekcija SARS-Cov-2 virusom bilo kog stepena težine povećava rizik za nastanak kogni- tivnog pada. Do sada nije istražen uticaj kognitivnog pada nakon COVID-19 na kvalitet života i aktivnosti svakodnevnog življenja, kao i uticaj psiholoških i so- cijalnih aspekata pandemije na kogniciju. Mogući mehanizmi kognitivne dis- fukcije su: direktna infekcija CNS-a, udaljeni efekti sistemske infekcije („cito- kinska oluja“ i dr.), vaskularno oštećenje mozga, neuroinflamacija, autoimuni odgovor protiv CNS-a, hipometabolizam limbičkog sistema i orbitofrontalnog korteksa, kao i neurodegeneracija slična onoj u Alchajmerovoj bolesti, pri čemu je moguće da se neki od ovih mehanizama prepliću.
Zaključak: Kognitive manifestacije „dugog COVID-a“ nisu retke i značajno uti- ču na povratak u uobičajeni lični i profesionalni milje preživelih. Neophodno je dugoročno praćenje ovih bolesnika i sagledavanje različitih etioloških i terapij- skih aspekata kognitivnih izmena u okviru „dugog COVID-a”.
AB  - Introduction: Although SARS-CoV-2 is a respiratory infection, the virus is neurotropic and neurological manifestations are seen in 40% patients. Recognition of prolonged post- COVID symptoms led to the introduction of the term “long COVID syndrome”, referring to a set of various symptoms persisting for a minimum of four weeks after acute infection. One of the main manifestations is cognitive decline.
Aim: Analysis of incidence and neuropsychological profile of cognitive decline in “long COVID” syndrome.
Method: Literature review.
Results: Most frequent CNS manifestations of “long COVID” include cognitive decline, headache, sleep disturbance, and dizziness. Cognitive changes are reported as “brain fog” and correspond to a decline in attention and short-term memory, impacting return to premorbid social and professional activities. Acute SARS-CoV-2 neurocognitive complications are seen particularly in critically ill and respiratory insufficient patients, comparable to the similar phenomenon of post-sepsis and intensive care unit treatment (“post-ICU syndrome”).
However, 20% of patients with mild COVID-19, not requiring hospitalization, also reported prolonged cognitive complaints, resembling those in patients with chronic fatigue syndrome.
SARS-Cov-2 infection of any severity increases the risk for cognitive decline. The impact of post-COVID cognitive decline on the quality of life and activities of daily living as well as the influence of psychological and social aspects of the pandemic on cognition remain to be investigated. Potential mechanisms of cognitive dysfunction are direct CNS infection, remote effects of systemic infection (“cytokine storm” etc.), vascular brain damage, neuroinflammation, autoimmune response directed to the CNS components, hypometabolism in the limbic and orbitofrontal cortex, as well as neurodegeneration comparable to those in Alzheimer’s disease. Several different mechanisms may also be intertwined.
Conclusion: Cognitive manifestations of “long COVID” are not rare and have a significant influence on personal and professional activities of the survivors. Long-term follow-up and analysis of various etiological and therapeutic aspects of cognitive changes within “long-COVID” are needed.
PB  - Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation
C3  - Zbornik radova - 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.
T1  - Neurokognitivni sindrom „dugog covid-a”: pregled literature
T1  - Neurocognitive syndrome of “long covid”: literature review
EP  - 239
SP  - 231
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_3776
ER  - 

@conference{
author = "Pavlović, Aleksandra and Milenković, Marija and Stevanović, Aleksandar and Pavlović, Dragan",
year = "2021",
abstract = "Uvod: Iako je SARS-CoV-2 respiratorna infekcija, virus je neurotropan i 40% bolesnika ima neurološke manifestacije. Česta pojava slučajeva sa produženim smetnjama posle COVID-19 nametnula je uvođenje sindroma „dugog COVID-a“, koji označava set različitih simptoma koji perzistiraju minimum četiri nedelje nakon akutne infekcije. Jedna od vodećih manifestacija je kognitivni pad.
Cilj: Analiza učestalosti i neuropsihološkog profila kognitivnog pada u „dugom COVID-u“.
Metod: Pregled literature.
Rezultati: Među CNS posledicama „dugog COVID-a“ najčešće se registruju ko- gnitivni pad, glavobolja, izmene sna i vrtoglavica. Kognitivne izmene bolesnici opisuju kao doživljaj postojanja „magle u glavi“, a podrazumeva pad koncen- tracije ili smetnje kratkoročnog pamćenja, koji može da utiče na povratak uo- bičajenom socijalnom i profesionalnom funkcionisanju. Neurokognitivne kom- plikacije akutne SARS-CoV-2 infekcije se opisuju naročito kod kritično obolelih i respiratorno ugroženih bolesnika i porede sa sličnim sindromima posle sepse ili boravka u jedinicama intenzivnog lečenja (“post-ICU syndrome“). Međutim, bar 20% bolesnika sa blagim formama COVID-19 koje nisu zahtevale hospita- lizaciju takođe ima produžene kognitivne smetnje. Fenomeni u sklopu „bra- in fog“ slični su onima kod osoba sa sindromom hroničnog umora. Infekcija SARS-Cov-2 virusom bilo kog stepena težine povećava rizik za nastanak kogni- tivnog pada. Do sada nije istražen uticaj kognitivnog pada nakon COVID-19 na kvalitet života i aktivnosti svakodnevnog življenja, kao i uticaj psiholoških i so- cijalnih aspekata pandemije na kogniciju. Mogući mehanizmi kognitivne dis- fukcije su: direktna infekcija CNS-a, udaljeni efekti sistemske infekcije („cito- kinska oluja“ i dr.), vaskularno oštećenje mozga, neuroinflamacija, autoimuni odgovor protiv CNS-a, hipometabolizam limbičkog sistema i orbitofrontalnog korteksa, kao i neurodegeneracija slična onoj u Alchajmerovoj bolesti, pri čemu je moguće da se neki od ovih mehanizama prepliću.
Zaključak: Kognitive manifestacije „dugog COVID-a“ nisu retke i značajno uti- ču na povratak u uobičajeni lični i profesionalni milje preživelih. Neophodno je dugoročno praćenje ovih bolesnika i sagledavanje različitih etioloških i terapij- skih aspekata kognitivnih izmena u okviru „dugog COVID-a”., Introduction: Although SARS-CoV-2 is a respiratory infection, the virus is neurotropic and neurological manifestations are seen in 40% patients. Recognition of prolonged post- COVID symptoms led to the introduction of the term “long COVID syndrome”, referring to a set of various symptoms persisting for a minimum of four weeks after acute infection. One of the main manifestations is cognitive decline.
Aim: Analysis of incidence and neuropsychological profile of cognitive decline in “long COVID” syndrome.
Method: Literature review.
Results: Most frequent CNS manifestations of “long COVID” include cognitive decline, headache, sleep disturbance, and dizziness. Cognitive changes are reported as “brain fog” and correspond to a decline in attention and short-term memory, impacting return to premorbid social and professional activities. Acute SARS-CoV-2 neurocognitive complications are seen particularly in critically ill and respiratory insufficient patients, comparable to the similar phenomenon of post-sepsis and intensive care unit treatment (“post-ICU syndrome”).
However, 20% of patients with mild COVID-19, not requiring hospitalization, also reported prolonged cognitive complaints, resembling those in patients with chronic fatigue syndrome.
SARS-Cov-2 infection of any severity increases the risk for cognitive decline. The impact of post-COVID cognitive decline on the quality of life and activities of daily living as well as the influence of psychological and social aspects of the pandemic on cognition remain to be investigated. Potential mechanisms of cognitive dysfunction are direct CNS infection, remote effects of systemic infection (“cytokine storm” etc.), vascular brain damage, neuroinflammation, autoimmune response directed to the CNS components, hypometabolism in the limbic and orbitofrontal cortex, as well as neurodegeneration comparable to those in Alzheimer’s disease. Several different mechanisms may also be intertwined.
Conclusion: Cognitive manifestations of “long COVID” are not rare and have a significant influence on personal and professional activities of the survivors. Long-term follow-up and analysis of various etiological and therapeutic aspects of cognitive changes within “long-COVID” are needed.",
publisher = "Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation",
journal = "Zbornik radova - 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.",
title = "Neurokognitivni sindrom „dugog covid-a”: pregled literature, Neurocognitive syndrome of “long covid”: literature review",
pages = "239-231",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_3776"
}

Pavlović, A., Milenković, M., Stevanović, A.,& Pavlović, D.. (2021). Neurokognitivni sindrom „dugog covid-a”: pregled literature. in Zbornik radova - 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.
Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation., 231-239.
https://hdl.handle.net/21.15107/rcub_rfasper_3776

Pavlović A, Milenković M, Stevanović A, Pavlović D. Neurokognitivni sindrom „dugog covid-a”: pregled literature. in Zbornik radova - 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.. 2021;:231-239.
https://hdl.handle.net/21.15107/rcub_rfasper_3776 .

Pavlović, Aleksandra, Milenković, Marija, Stevanović, Aleksandar, Pavlović, Dragan, "Neurokognitivni sindrom „dugog covid-a”: pregled literature" in Zbornik radova - 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021. (2021):231-239,
https://hdl.handle.net/21.15107/rcub_rfasper_3776 .

TY  - CONF
AU  - Pavlović, Dragan
AU  - Pavlović, Aleksandra
AU  - Milenković, Marija
PY  - 2021
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/3695
AB  - Uvod: Cink je drugi najzastupljeniji esencijalni metal u organizmu i jedini koji je prisutan u svim klasama enzima. Cink se resorbuje u tankom crevu. Nema depoa cinka u organizmu. On se izlučuje putem bubrega, kože i creva. Hrana životinjskog porekla ima manje cinka ali nema fitata pa je dobar izvor cinka.
Cilj: Cilj rada je da se pregledom relevantne literature izdvoje istraživanja koja potvrđuju značaj cinka u radu mozga i razvoju dece.
Metod: Izvršeno je pretraživanje baze podataka Pub Med korišćenjem ključnih reči cink, mozak, kognicija, deca.
Rezultati: Cink je neophodan za funkcionisanje centralnog nervnog sistema, učestvuje u neurotransmisiji, posebno u hipokampusu gde reguliše glutamate i gamaaminobuternu kiselinu koji su najzastupljeniji neurotransmiteri u mozgu. Ovim se omogućuju normalne kognitivne funkcije. Osim u prenosu informacija, cink u mozgu omogućava i metabolizam DNK, rast moždanog tubulina i fosforilaciju. Cink stabilizuje ćelijske membrane i druge ćelijske komponente i bitan je za transkripciju polinukleotida u procesu genetske ekspresije. Cink omogućava deobu, rast i diferencijaciju ćelija, što je bitno za intrauterini razvoj ploda, stimuliše rast i razvoj organizma, a važan je i za čulo ukusa i mirisa. Cink je kritičan za rast i razvoj mozga, u sintezi DNK, RNK i proteina, pa nedostatak cinka u intrauterinom period može da dovede do malformacija mozga, a kod dece do sporijeg i slabijeg razvoja. Smatra se da kao posledica nedostatka cinka u svetu godišnje umre oko 800,000 dece. Manjak cinka dovodi do usporenja rasta i razvoja kod dece, usporenja seksualnog razvoja, gubitka apetita, poremećaja imuniteta, dijareje, muškog hipogonadizma, infertiliteta i oštećenja oka.
Zaključak: Cink je ključan mikronutrijent za rad neurona i veoma je bitan u normalnom razvoju dece. Balans cinka je neophodno postići tokom celog života čoveka kako bi se omogućio normalan razvoj i kognicija.
AB  - Introduction: Zinc is the second most abundant essential metal in the body and the only one present in all classes of enzymes. Zinc is absorbed in the small intestine. There is no zinc depot in the body. It is excreted through the kidneys, skin and intestines. Foods of animal origin have less zinc but no phytate so they are a good source of zinc.
Aim: The aim of this paper is to examine the importance of zinc in brain function and child development.
Method: The Pub Med database was searched using the keywords zinc, brain, cognition, children.
Results: Zinc is necessary for the functioning of the central nervous system, it participates in neurotransmission, especially in the hippocampus, where it regulates glutamate and gamma-aminobutyric acid, which are the most common neurotransmitters in the brain. This allows for normal cognitive functions. In addition to transmitting information, zinc in the brain also enables DNA metabolism, brain tubulin growth and phosphorylation. Zinc stabilizes cell membranes and other cell components and is essential for the transcription of polynucleotides in the process of genetic expression. Zinc balance disorder occurs in Alzheimer’s disease, depression, etc. Zinc enables cell division, growth and differentiation, which is important for the intrauterine development of the fetus, stimulates the growth and development of the organism, and is also important for the sense of taste and smell. Zinc is critical for the growth and development of the brain, in the synthesis of DNA, RNA and proteins, so the lack of zinc in the intrauterine period can lead to brain malformations, and in children to slower and weaker development. It is estimated that around 800,000 children die each year as a result of zinc deficiency in the world. Zinc deficiency leads to growth retardation and development in children, slowing of sexual development, loss of appetite, immune disorders, diarrhea, male hypogonadism, infertility and eye damage.
Conclusion: Zinc is a key micronutrient for the work of neurons and is very important in the normal development of children. Zinc balance is necessary to be achieved throughout a person’s life in order to enable normal development and cognition.
PB  - Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation
C3  - Zbornik rezimea – 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.
T1  - Značaj cinka u radu mozga i razvoju dece – narativni prikaz
T1  - The importance of zinc in brain function and child development – a narrative review
EP  - 102
SP  - 101
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_3695
ER  - 

@conference{
author = "Pavlović, Dragan and Pavlović, Aleksandra and Milenković, Marija",
year = "2021",
abstract = "Uvod: Cink je drugi najzastupljeniji esencijalni metal u organizmu i jedini koji je prisutan u svim klasama enzima. Cink se resorbuje u tankom crevu. Nema depoa cinka u organizmu. On se izlučuje putem bubrega, kože i creva. Hrana životinjskog porekla ima manje cinka ali nema fitata pa je dobar izvor cinka.
Cilj: Cilj rada je da se pregledom relevantne literature izdvoje istraživanja koja potvrđuju značaj cinka u radu mozga i razvoju dece.
Metod: Izvršeno je pretraživanje baze podataka Pub Med korišćenjem ključnih reči cink, mozak, kognicija, deca.
Rezultati: Cink je neophodan za funkcionisanje centralnog nervnog sistema, učestvuje u neurotransmisiji, posebno u hipokampusu gde reguliše glutamate i gamaaminobuternu kiselinu koji su najzastupljeniji neurotransmiteri u mozgu. Ovim se omogućuju normalne kognitivne funkcije. Osim u prenosu informacija, cink u mozgu omogućava i metabolizam DNK, rast moždanog tubulina i fosforilaciju. Cink stabilizuje ćelijske membrane i druge ćelijske komponente i bitan je za transkripciju polinukleotida u procesu genetske ekspresije. Cink omogućava deobu, rast i diferencijaciju ćelija, što je bitno za intrauterini razvoj ploda, stimuliše rast i razvoj organizma, a važan je i za čulo ukusa i mirisa. Cink je kritičan za rast i razvoj mozga, u sintezi DNK, RNK i proteina, pa nedostatak cinka u intrauterinom period može da dovede do malformacija mozga, a kod dece do sporijeg i slabijeg razvoja. Smatra se da kao posledica nedostatka cinka u svetu godišnje umre oko 800,000 dece. Manjak cinka dovodi do usporenja rasta i razvoja kod dece, usporenja seksualnog razvoja, gubitka apetita, poremećaja imuniteta, dijareje, muškog hipogonadizma, infertiliteta i oštećenja oka.
Zaključak: Cink je ključan mikronutrijent za rad neurona i veoma je bitan u normalnom razvoju dece. Balans cinka je neophodno postići tokom celog života čoveka kako bi se omogućio normalan razvoj i kognicija., Introduction: Zinc is the second most abundant essential metal in the body and the only one present in all classes of enzymes. Zinc is absorbed in the small intestine. There is no zinc depot in the body. It is excreted through the kidneys, skin and intestines. Foods of animal origin have less zinc but no phytate so they are a good source of zinc.
Aim: The aim of this paper is to examine the importance of zinc in brain function and child development.
Method: The Pub Med database was searched using the keywords zinc, brain, cognition, children.
Results: Zinc is necessary for the functioning of the central nervous system, it participates in neurotransmission, especially in the hippocampus, where it regulates glutamate and gamma-aminobutyric acid, which are the most common neurotransmitters in the brain. This allows for normal cognitive functions. In addition to transmitting information, zinc in the brain also enables DNA metabolism, brain tubulin growth and phosphorylation. Zinc stabilizes cell membranes and other cell components and is essential for the transcription of polynucleotides in the process of genetic expression. Zinc balance disorder occurs in Alzheimer’s disease, depression, etc. Zinc enables cell division, growth and differentiation, which is important for the intrauterine development of the fetus, stimulates the growth and development of the organism, and is also important for the sense of taste and smell. Zinc is critical for the growth and development of the brain, in the synthesis of DNA, RNA and proteins, so the lack of zinc in the intrauterine period can lead to brain malformations, and in children to slower and weaker development. It is estimated that around 800,000 children die each year as a result of zinc deficiency in the world. Zinc deficiency leads to growth retardation and development in children, slowing of sexual development, loss of appetite, immune disorders, diarrhea, male hypogonadism, infertility and eye damage.
Conclusion: Zinc is a key micronutrient for the work of neurons and is very important in the normal development of children. Zinc balance is necessary to be achieved throughout a person’s life in order to enable normal development and cognition.",
publisher = "Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation",
journal = "Zbornik rezimea – 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.",
title = "Značaj cinka u radu mozga i razvoju dece – narativni prikaz, The importance of zinc in brain function and child development – a narrative review",
pages = "102-101",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_3695"
}

Pavlović, D., Pavlović, A.,& Milenković, M.. (2021). Značaj cinka u radu mozga i razvoju dece – narativni prikaz. in Zbornik rezimea – 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.
Univerzitet u Beogradu – Fakultet za specijalnu edukaciju i rehabilitaciju / University of Belgrade – Faculty of Special Education and Rehabilitation., 101-102.
https://hdl.handle.net/21.15107/rcub_rfasper_3695

Pavlović D, Pavlović A, Milenković M. Značaj cinka u radu mozga i razvoju dece – narativni prikaz. in Zbornik rezimea – 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021.. 2021;:101-102.
https://hdl.handle.net/21.15107/rcub_rfasper_3695 .

Pavlović, Dragan, Pavlović, Aleksandra, Milenković, Marija, "Značaj cinka u radu mozga i razvoju dece – narativni prikaz" in Zbornik rezimea – 11. Međunarodni naučni skup „Specijalna edukacija i rehabilitacija danas“, Beograd, Srbija, 29–30.10.2021. (2021):101-102,
https://hdl.handle.net/21.15107/rcub_rfasper_3695 .

TY  - JOUR
AU  - Pavlović, Dragan
AU  - Đorđević, Jelena
AU  - Pavlović, Aleksandra M.
AU  - Stjepanović, Mirjana
AU  - Baralić, Marko
PY  - 2021
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/1330
AB  - Myalgic encephalomyelitis is a complex, multisystem disease with chronic course significantly affecting patients' quality of life. Physical and mental exertion intolerability, muscle pain, and sleep problems are the main features accompanied often with cognitive inefficacy and vegetative symptoms. Prevalence is 7-3000 per 100,000 adults. It is estimated that 90% of the patients are misdiagnosed. Pathogenesis is still only speculative but current research points to disturbances in the immunological system, inflammatory pathways, autonomic and central nervous system, muscle and mitochondria, as well as alterations of gut microbiota and gut permeability. The onset is typically acute, following an infectious disease. Exertional intolerance lasting for more than six months is an important diagnostic factor. The core features must be moderate to severe and present at least 50% of the time. Diagnostic criteria should be fulfilled and differential diagnosis should be made to exclude other potential pathological conditions or to diagnose comorbidities. Brain magnetic resonance imaging morphometry has shown gray matter atrophy in occipital lobes bilaterally, right angular gyrus, and the posterior division of the left parahippocampal gyrus, consistent with memory problems and potentially with impairment of visual processing. Treatment is still symptomatic and of partial benefit. Symptomatic treatment can include medications for controlling pain and sleep problems, graded exercise and cognitive behavioral therapy. Larger controlled trials are needed to shed more light on this challenging condition.
AB  - Mijalgični encefalomijelitis je složeno, multisistemsko oboljenje sa hroničnim tokom koje značajno utiče na kvalitet života bolesnika. Slaba tolerancija na fizički i mentalni napor, bolovi u mišićima i problemi sa spavanjem glavne su odlike i često su praćene kognitivnom neefikasnošću i vegetativnim simptomima. Prevalencija je 7-3000 na 100.000 odraslih. Procenjuje se da je 90% ovih bolesnika pogrešno dijagnostikovano. Patogeneza je i dalje samo spekulativna, ali trenutna istraživanja ukazuju na poremećaje u imunološkom sistemu, inflamatornom odgovoru, autonomnom i centralnom nervnom sistemu, mišićima i mitohondrijama, kao i promene mikrobiote i propustljivosti creva. Početak bolesti je tipično akutan i prati infektivnu bolest. Netolerancija napora koja traje duže od šest meseci važan je dijagnostički kriterijum. Osnovne karakteristike moraju biti umerene do teške i prisutne najmanje 50% vremena. Isključivanje drugih mogućih patoloških stanja ili komorbiditetnih dijagnoza zahteva zadovoljavanje dijagnostičkih kriterijuma i diferencijalno dijagnostičko sagledavanje. Morfometrijska snimanja mozga magnetnom rezonancom pokazala su atrofiju sive mase u okcipitalnim režnjevima bilateralno, desnom angularnom girusu i posteriornom levom parahipokampalnom girusu, što može dovesti do problema sa pamćenjem i oštećenja vizuelne obrade informacija. Lečenje je i dalje simptomatsko i samo delimično uspešno. Simptomatski tretman može da uključuje lekove za kontrolu bola i problema sa spavanjem, doziranu fizičku aktivnost i kognitivno-bihevioralnu terapiju. Potrebne su veće studije da bi se razjasnilo ovo medicinsko stanje.
PB  - Srpsko lekarsko društvo, Beograd
T2  - Srpski arhiv za celokupno lekarstvo
T1  - Myalgic encephalomyelitis: Enigma at the medicine's crossroads
T1  - Mijalgični encefalomijelitis - enigma na raskršću medicine
EP  - 110
IS  - 1-2
SP  - 105
VL  - 149
DO  - 10.2298/SARH200628091P
ER  - 

@article{
author = "Pavlović, Dragan and Đorđević, Jelena and Pavlović, Aleksandra M. and Stjepanović, Mirjana and Baralić, Marko",
year = "2021",
abstract = "Myalgic encephalomyelitis is a complex, multisystem disease with chronic course significantly affecting patients' quality of life. Physical and mental exertion intolerability, muscle pain, and sleep problems are the main features accompanied often with cognitive inefficacy and vegetative symptoms. Prevalence is 7-3000 per 100,000 adults. It is estimated that 90% of the patients are misdiagnosed. Pathogenesis is still only speculative but current research points to disturbances in the immunological system, inflammatory pathways, autonomic and central nervous system, muscle and mitochondria, as well as alterations of gut microbiota and gut permeability. The onset is typically acute, following an infectious disease. Exertional intolerance lasting for more than six months is an important diagnostic factor. The core features must be moderate to severe and present at least 50% of the time. Diagnostic criteria should be fulfilled and differential diagnosis should be made to exclude other potential pathological conditions or to diagnose comorbidities. Brain magnetic resonance imaging morphometry has shown gray matter atrophy in occipital lobes bilaterally, right angular gyrus, and the posterior division of the left parahippocampal gyrus, consistent with memory problems and potentially with impairment of visual processing. Treatment is still symptomatic and of partial benefit. Symptomatic treatment can include medications for controlling pain and sleep problems, graded exercise and cognitive behavioral therapy. Larger controlled trials are needed to shed more light on this challenging condition., Mijalgični encefalomijelitis je složeno, multisistemsko oboljenje sa hroničnim tokom koje značajno utiče na kvalitet života bolesnika. Slaba tolerancija na fizički i mentalni napor, bolovi u mišićima i problemi sa spavanjem glavne su odlike i često su praćene kognitivnom neefikasnošću i vegetativnim simptomima. Prevalencija je 7-3000 na 100.000 odraslih. Procenjuje se da je 90% ovih bolesnika pogrešno dijagnostikovano. Patogeneza je i dalje samo spekulativna, ali trenutna istraživanja ukazuju na poremećaje u imunološkom sistemu, inflamatornom odgovoru, autonomnom i centralnom nervnom sistemu, mišićima i mitohondrijama, kao i promene mikrobiote i propustljivosti creva. Početak bolesti je tipično akutan i prati infektivnu bolest. Netolerancija napora koja traje duže od šest meseci važan je dijagnostički kriterijum. Osnovne karakteristike moraju biti umerene do teške i prisutne najmanje 50% vremena. Isključivanje drugih mogućih patoloških stanja ili komorbiditetnih dijagnoza zahteva zadovoljavanje dijagnostičkih kriterijuma i diferencijalno dijagnostičko sagledavanje. Morfometrijska snimanja mozga magnetnom rezonancom pokazala su atrofiju sive mase u okcipitalnim režnjevima bilateralno, desnom angularnom girusu i posteriornom levom parahipokampalnom girusu, što može dovesti do problema sa pamćenjem i oštećenja vizuelne obrade informacija. Lečenje je i dalje simptomatsko i samo delimično uspešno. Simptomatski tretman može da uključuje lekove za kontrolu bola i problema sa spavanjem, doziranu fizičku aktivnost i kognitivno-bihevioralnu terapiju. Potrebne su veće studije da bi se razjasnilo ovo medicinsko stanje.",
publisher = "Srpsko lekarsko društvo, Beograd",
journal = "Srpski arhiv za celokupno lekarstvo",
title = "Myalgic encephalomyelitis: Enigma at the medicine's crossroads, Mijalgični encefalomijelitis - enigma na raskršću medicine",
pages = "110-105",
number = "1-2",
volume = "149",
doi = "10.2298/SARH200628091P"
}

Pavlović, D., Đorđević, J., Pavlović, A. M., Stjepanović, M.,& Baralić, M.. (2021). Myalgic encephalomyelitis: Enigma at the medicine's crossroads. in Srpski arhiv za celokupno lekarstvo
Srpsko lekarsko društvo, Beograd., 149(1-2), 105-110.
https://doi.org/10.2298/SARH200628091P

Pavlović D, Đorđević J, Pavlović AM, Stjepanović M, Baralić M. Myalgic encephalomyelitis: Enigma at the medicine's crossroads. in Srpski arhiv za celokupno lekarstvo. 2021;149(1-2):105-110.
doi:10.2298/SARH200628091P .

Pavlović, Dragan, Đorđević, Jelena, Pavlović, Aleksandra M., Stjepanović, Mirjana, Baralić, Marko, "Myalgic encephalomyelitis: Enigma at the medicine's crossroads" in Srpski arhiv za celokupno lekarstvo, 149, no. 1-2 (2021):105-110,
https://doi.org/10.2298/SARH200628091P . .

TY  - JOUR
AU  - Zelić, Mirna
AU  - Petrović Lazić, Mirjana
AU  - Pavlović, Dragan
PY  - 2021
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/4498
AB  - Dysphagia is a swallowing disorder that is characterized by difficulty to swallow and to control saliva as well as by feeding difficulties. Dysphagia is a common symptom of laryngeal cancer, or a consequence of surgical treatment as well as radiotherapy and chemotherapy of this neoplasma. The patients after laryngectomy are at risk of developing malnutrition, and aspiration pneumonia. Removal of anatomical structures and reorganization of remaining tissues has a significant impact on the physiology of swallowing. For most patients, safe swallowing is the main feature of a positive treatment outcome. Swallowing therapy is important before, during and after treatment of larynx cancer. The aim of this paper is to explore a correlation between swallowing disorders and laryngeal cancer treatment, and to understand the anatomical and physiological bases of dysphagia treatment
AB  - Disfagiju definišemo kao poremećaj gutanja. Poremećaji gutanja obuhvataju kako teškoće u gutanju i kontrolisanju pljuvačke, tako i teškoće u hranjenju. Disfagija podrazumeva čest simptom karcinoma larinksa, ali i posledicu hirurškog lečenja kao i radioterapije i hemoterapije ove neoplazme. Laringektomirani bolesnici su u riziku za malnutriciju i pneumoniju. Uklanjanje ključnih anatomskih struktura i reorganizacija preostalih tkiva ima značajan uticaj na fiziologiju gutanja. Izbor tretmana lečenja za očuvanje funkcije gutanja najvažnije je pitanje. Za većinu pacijenata bezbedno gutanje je glavna odlika pozitivnog ishoda lečenja. Tretman poremećaja gutanja je važna karika pre, u toku i nakon lečenja. Cilj rada bio je da se utvrdi korelacija između poremećaja gutanja, lečenja karcinoma larinksa, laringektomije kao izbora lečenja, odnosno razumevanje anatomskih i fizioloških osnova tretmana disfagija.
PB  - Srpsko lekarsko društvo - Okružna podružnica Kragujevac, Kragujevac
T2  - Medicinski časopis
T1  - Swallowing disorders during and after the treatment of larynx cancer
T1  - Poremećaji gutanja u toku i nakon lečenja karcinoma larinksa
EP  - 39
IS  - 1
SP  - 33
VL  - 55
DO  - 10.5937/mckg55-31139
ER  - 

@article{
author = "Zelić, Mirna and Petrović Lazić, Mirjana and Pavlović, Dragan",
year = "2021",
abstract = "Dysphagia is a swallowing disorder that is characterized by difficulty to swallow and to control saliva as well as by feeding difficulties. Dysphagia is a common symptom of laryngeal cancer, or a consequence of surgical treatment as well as radiotherapy and chemotherapy of this neoplasma. The patients after laryngectomy are at risk of developing malnutrition, and aspiration pneumonia. Removal of anatomical structures and reorganization of remaining tissues has a significant impact on the physiology of swallowing. For most patients, safe swallowing is the main feature of a positive treatment outcome. Swallowing therapy is important before, during and after treatment of larynx cancer. The aim of this paper is to explore a correlation between swallowing disorders and laryngeal cancer treatment, and to understand the anatomical and physiological bases of dysphagia treatment, Disfagiju definišemo kao poremećaj gutanja. Poremećaji gutanja obuhvataju kako teškoće u gutanju i kontrolisanju pljuvačke, tako i teškoće u hranjenju. Disfagija podrazumeva čest simptom karcinoma larinksa, ali i posledicu hirurškog lečenja kao i radioterapije i hemoterapije ove neoplazme. Laringektomirani bolesnici su u riziku za malnutriciju i pneumoniju. Uklanjanje ključnih anatomskih struktura i reorganizacija preostalih tkiva ima značajan uticaj na fiziologiju gutanja. Izbor tretmana lečenja za očuvanje funkcije gutanja najvažnije je pitanje. Za većinu pacijenata bezbedno gutanje je glavna odlika pozitivnog ishoda lečenja. Tretman poremećaja gutanja je važna karika pre, u toku i nakon lečenja. Cilj rada bio je da se utvrdi korelacija između poremećaja gutanja, lečenja karcinoma larinksa, laringektomije kao izbora lečenja, odnosno razumevanje anatomskih i fizioloških osnova tretmana disfagija.",
publisher = "Srpsko lekarsko društvo - Okružna podružnica Kragujevac, Kragujevac",
journal = "Medicinski časopis",
title = "Swallowing disorders during and after the treatment of larynx cancer, Poremećaji gutanja u toku i nakon lečenja karcinoma larinksa",
pages = "39-33",
number = "1",
volume = "55",
doi = "10.5937/mckg55-31139"
}

Zelić, M., Petrović Lazić, M.,& Pavlović, D.. (2021). Swallowing disorders during and after the treatment of larynx cancer. in Medicinski časopis
Srpsko lekarsko društvo - Okružna podružnica Kragujevac, Kragujevac., 55(1), 33-39.
https://doi.org/10.5937/mckg55-31139

Zelić M, Petrović Lazić M, Pavlović D. Swallowing disorders during and after the treatment of larynx cancer. in Medicinski časopis. 2021;55(1):33-39.
doi:10.5937/mckg55-31139 .

Zelić, Mirna, Petrović Lazić, Mirjana, Pavlović, Dragan, "Swallowing disorders during and after the treatment of larynx cancer" in Medicinski časopis, 55, no. 1 (2021):33-39,
https://doi.org/10.5937/mckg55-31139 . .

TY  - JOUR
AU  - Zelić, Mirna
AU  - Todorović, Jelena
AU  - Pavlović, Dragan
AU  - Jerkić, Lana
PY  - 2021
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/1321
AB  - Swallowing disorders (dysphagia) include difficulty in swallowing and controlling saliva, as well as feeding difficulties. These disorders affect all age groups from newborns to the elderly and can be the result of congenital abnormalities, damage of anatomical structures that affect swallowing, as well as various medical conditions. Dysphagia may be acute (eg. stroke) or may progress over time (eg. tumors and progressive neurological diseases). Numerous regions participate in the act of swallowing and they include precentral gyrus, postcentral gyrus, premotor zone, the supplementary motor area, operculum, insula, precuneus, prefrontal cortex, temporal lobe, cerebellum, brainstem, the frontal lobe, association areas, thalamus, and basal ganglia. It is extremely important to understand the swallowing process in order to further give an adequate approach in the treatment of disorders of this function.
AB  - Poremećaji gutanja (disfagija) obuhvataju kako teškoće u gutanju i kontrolisanju pljuvačke, tako i teškoće prilikom hranjenja. Ove smetnje pogađaju sve starosne grupe, od novorođenčeta do starijih i mogu biti posledica kongenitalnih abnormalnosti, oštećenja anatomskih struktura, koje utiču na gutanje, kao i različitih medicinskih stanja. Disfagija može da bude akutna (npr. izazvana moždanim udarom) ili može da progredira tokom vremena (npr. izazvana tumorima i progresivnim neurološkim bolestima). Brojne regije učestvuju u aktu gutanja i uključuju precentralni girus, postcentralni girus, premotornu zonu, suplementarnu motornu zonu, operculum, insulu, precuneus, prefrontalnu areu, temporalni režanj, Mali mozak, moždano stablo, frontalni režanj, capsulu interna, asocijativna polja, talamus i bazalne ganglije. Od izuzetne je važnosti razumevanje procesa gutanja, radi daljeg planiranja adekvatnog pristupa u tretmanu poremećaja ove funkcije.
PB  - Univerzitet u Nišu - Medicinski fakultet, Niš
T2  - Acta medica Medianae
T1  - The relationship between lesion localization and swallowing disorders
T1  - Poremećaji gutanja u odnosu na lokalizaciju moždanih lezija
EP  - 91
IS  - 1
SP  - 85
VL  - 60
DO  - 10.5633/amm.2021.0112
ER  - 

@article{
author = "Zelić, Mirna and Todorović, Jelena and Pavlović, Dragan and Jerkić, Lana",
year = "2021",
abstract = "Swallowing disorders (dysphagia) include difficulty in swallowing and controlling saliva, as well as feeding difficulties. These disorders affect all age groups from newborns to the elderly and can be the result of congenital abnormalities, damage of anatomical structures that affect swallowing, as well as various medical conditions. Dysphagia may be acute (eg. stroke) or may progress over time (eg. tumors and progressive neurological diseases). Numerous regions participate in the act of swallowing and they include precentral gyrus, postcentral gyrus, premotor zone, the supplementary motor area, operculum, insula, precuneus, prefrontal cortex, temporal lobe, cerebellum, brainstem, the frontal lobe, association areas, thalamus, and basal ganglia. It is extremely important to understand the swallowing process in order to further give an adequate approach in the treatment of disorders of this function., Poremećaji gutanja (disfagija) obuhvataju kako teškoće u gutanju i kontrolisanju pljuvačke, tako i teškoće prilikom hranjenja. Ove smetnje pogađaju sve starosne grupe, od novorođenčeta do starijih i mogu biti posledica kongenitalnih abnormalnosti, oštećenja anatomskih struktura, koje utiču na gutanje, kao i različitih medicinskih stanja. Disfagija može da bude akutna (npr. izazvana moždanim udarom) ili može da progredira tokom vremena (npr. izazvana tumorima i progresivnim neurološkim bolestima). Brojne regije učestvuju u aktu gutanja i uključuju precentralni girus, postcentralni girus, premotornu zonu, suplementarnu motornu zonu, operculum, insulu, precuneus, prefrontalnu areu, temporalni režanj, Mali mozak, moždano stablo, frontalni režanj, capsulu interna, asocijativna polja, talamus i bazalne ganglije. Od izuzetne je važnosti razumevanje procesa gutanja, radi daljeg planiranja adekvatnog pristupa u tretmanu poremećaja ove funkcije.",
publisher = "Univerzitet u Nišu - Medicinski fakultet, Niš",
journal = "Acta medica Medianae",
title = "The relationship between lesion localization and swallowing disorders, Poremećaji gutanja u odnosu na lokalizaciju moždanih lezija",
pages = "91-85",
number = "1",
volume = "60",
doi = "10.5633/amm.2021.0112"
}

Zelić, M., Todorović, J., Pavlović, D.,& Jerkić, L.. (2021). The relationship between lesion localization and swallowing disorders. in Acta medica Medianae
Univerzitet u Nišu - Medicinski fakultet, Niš., 60(1), 85-91.
https://doi.org/10.5633/amm.2021.0112

Zelić M, Todorović J, Pavlović D, Jerkić L. The relationship between lesion localization and swallowing disorders. in Acta medica Medianae. 2021;60(1):85-91.
doi:10.5633/amm.2021.0112 .

Zelić, Mirna, Todorović, Jelena, Pavlović, Dragan, Jerkić, Lana, "The relationship between lesion localization and swallowing disorders" in Acta medica Medianae, 60, no. 1 (2021):85-91,
https://doi.org/10.5633/amm.2021.0112 . .

TY  - CONF
AU  - Aleksić, Vuk
AU  - Rapaić, Dragan
AU  - Pavlović, Dragan
AU  - Marinković, Dragan
AU  - Đurović, Branko
AU  - Ilić, Rosanda
AU  - Đurović, Marko
AU  - Cvrkota, Irena
AU  - Rapaić, Marko
PY  - 2020
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/3252
AB  - Patients with traumatic brain injury (TBI) may have significant cognitive deficit and rehabilitation is based on the improvement of remaining abilities aiming to bring the person closer to premorbid profile. The aim of this study was to compare attention, memory and constructive-praxis state between healthy individuals and TBI patients before and after 4-weeks of special neurorehabilitation therapy. The experimental group
(E) consisted of 15 patients with brain injury, while the control group (C) consisted of 15 healthy subjects. The assessment instruments were the subtests of "Attention" and "Memory" tests, and performed before and after the 4-weeks-therapy (focus, attention transfer, memory, and constructive practice therapy). Descriptive statistical methods and two-factor-analysis of variance was used as analytical statistical methods, where one factor represented group affiliation and the other was measurement (before and after therapy). The difference significance was determined at the level of error probability of type Ia = 0.05 (statistically significant difference p < 0.05, highly statistically significant difference p < 0.01). Results showed that all groups had 15 respondent (10 men, 5 women), ages between 15 and 18 years. In all tests high statistically significant difference between E and C group was found on the first measurement. Statistically significant difference between subjects of both groups on the second measurement was also found. High statistically significant difference of the E group on the first and second measurement was found. It can be said that applied therapies were effective. However, patients demonstrated lower score on tests after therapy than their healthy matches, indicating that four-week-therapy is not sufficient and should be continued.
PB  - University of Belgrade – Faculty of Special Education and Rehabilitation
Publishing Center of the Faculty
C3  - Approaches and Models in Special Education and Rehabilitation – Thematic Collection of International Importance
T1  - Neurorehabilitation in patients with traumatic brain injury
EP  - 327
SP  - 317
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_3252
ER  - 

@conference{
author = "Aleksić, Vuk and Rapaić, Dragan and Pavlović, Dragan and Marinković, Dragan and Đurović, Branko and Ilić, Rosanda and Đurović, Marko and Cvrkota, Irena and Rapaić, Marko",
year = "2020",
abstract = "Patients with traumatic brain injury (TBI) may have significant cognitive deficit and rehabilitation is based on the improvement of remaining abilities aiming to bring the person closer to premorbid profile. The aim of this study was to compare attention, memory and constructive-praxis state between healthy individuals and TBI patients before and after 4-weeks of special neurorehabilitation therapy. The experimental group
(E) consisted of 15 patients with brain injury, while the control group (C) consisted of 15 healthy subjects. The assessment instruments were the subtests of "Attention" and "Memory" tests, and performed before and after the 4-weeks-therapy (focus, attention transfer, memory, and constructive practice therapy). Descriptive statistical methods and two-factor-analysis of variance was used as analytical statistical methods, where one factor represented group affiliation and the other was measurement (before and after therapy). The difference significance was determined at the level of error probability of type Ia = 0.05 (statistically significant difference p < 0.05, highly statistically significant difference p < 0.01). Results showed that all groups had 15 respondent (10 men, 5 women), ages between 15 and 18 years. In all tests high statistically significant difference between E and C group was found on the first measurement. Statistically significant difference between subjects of both groups on the second measurement was also found. High statistically significant difference of the E group on the first and second measurement was found. It can be said that applied therapies were effective. However, patients demonstrated lower score on tests after therapy than their healthy matches, indicating that four-week-therapy is not sufficient and should be continued.",
publisher = "University of Belgrade – Faculty of Special Education and Rehabilitation
Publishing Center of the Faculty",
journal = "Approaches and Models in Special Education and Rehabilitation – Thematic Collection of International Importance",
title = "Neurorehabilitation in patients with traumatic brain injury",
pages = "327-317",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_3252"
}

Aleksić, V., Rapaić, D., Pavlović, D., Marinković, D., Đurović, B., Ilić, R., Đurović, M., Cvrkota, I.,& Rapaić, M.. (2020). Neurorehabilitation in patients with traumatic brain injury. in Approaches and Models in Special Education and Rehabilitation – Thematic Collection of International Importance
University of Belgrade – Faculty of Special Education and Rehabilitation
Publishing Center of the Faculty., 317-327.
https://hdl.handle.net/21.15107/rcub_rfasper_3252

Aleksić V, Rapaić D, Pavlović D, Marinković D, Đurović B, Ilić R, Đurović M, Cvrkota I, Rapaić M. Neurorehabilitation in patients with traumatic brain injury. in Approaches and Models in Special Education and Rehabilitation – Thematic Collection of International Importance. 2020;:317-327.
https://hdl.handle.net/21.15107/rcub_rfasper_3252 .

Aleksić, Vuk, Rapaić, Dragan, Pavlović, Dragan, Marinković, Dragan, Đurović, Branko, Ilić, Rosanda, Đurović, Marko, Cvrkota, Irena, Rapaić, Marko, "Neurorehabilitation in patients with traumatic brain injury" in Approaches and Models in Special Education and Rehabilitation – Thematic Collection of International Importance (2020):317-327,
https://hdl.handle.net/21.15107/rcub_rfasper_3252 .

TY  - CONF
AU  - Pavlović, Aleksandra
AU  - Pavlović, Dragan
PY  - 2020
UR  - http://www.icf.fasper.bg.ac.rs/zbornici/20201221_1-ZBORNIK-RADOVA-SKUP-NAC_2020.pdf
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/3467
AB  - Adults with Down syndrome are at an
increased risk of developing early onset
Alzheimer’s diseasе. Dementia is typically
preceded by prodromal pre-clinical phase.
Pathohistological characteristics of Alzheimer’s diseasе are universally present
by the fifth decade in Down syndrome
patients. Trajectories of cognitive decline
associated with dementia in Down syndrome
population are not fully described. Having
in mind pre-existing cognitive difficulties, early dementia signs may be overlooked or misdiagnosed, missing the opportunity
for the early use of pharmacological and
psychosocial interventions. Down syndrome
population could be a target for investigation
of preventive and therapeutic measures in
management of Alzheimer’s diseasе. World
Heаlth Organisation called for inclusion of
intellectual disability in national dementia
plans.
AB  - Odrasle osobe sa Daunovim sindromom su u velikom riziku za razvoj Alchajmerove bolesti ranog početka. Demenciji prethodi period prodromalne, pre-kliničke faze. Histopatološki nalazi karakteristični za Alchajmerovu bolest su gotovo pravilo kod osoba sa Daunovim sindromom u petoj deceniji života. Trajektorije kognitivnog propadanja kod populacije sa Daunovim sindromom nisu u potpunosti definisane. Budući da kod ovih osoba već postoji intelektu- alna ometenost, suptilni rani znaci kognitivnog pada se mogu prevideti ili pogrešno dijagnostikovati čime se propušta prilika za pravovremenu pri- menu farmakoloških i psihosocijalnih intervencija. Populacija sa Daunovim sindromom bi mogla biti ciljna za ispitivanje preventivnih i terapijski mera za nastanak Alchajmerove bolesti. Iz ovih razloga, Svetska zdravstvena organizacija je pozvala na uključivanje intelektualne ometenosti u nacional- ne planove za demenciju.
PB  - Univerzitet u Beogradu - Fakultet za specijalnu edukaciju i rehabilitaciju
C3  - Nacionalni naučni skup „Evaluacija efekata inkluzivnog obrazovanja u republici Srbiji” - Zbornik radova
T1  - intelektualna ometenost i razvoj demencije: demencija kod osoba sa daunovim sindromom
T1  - Intellectual disability and development of dementia: dementia in persons with down syndrome
EP  - 223
SP  - 217
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_3467
ER  - 

@conference{
author = "Pavlović, Aleksandra and Pavlović, Dragan",
year = "2020",
abstract = "Adults with Down syndrome are at an
increased risk of developing early onset
Alzheimer’s diseasе. Dementia is typically
preceded by prodromal pre-clinical phase.
Pathohistological characteristics of Alzheimer’s diseasе are universally present
by the fifth decade in Down syndrome
patients. Trajectories of cognitive decline
associated with dementia in Down syndrome
population are not fully described. Having
in mind pre-existing cognitive difficulties, early dementia signs may be overlooked or misdiagnosed, missing the opportunity
for the early use of pharmacological and
psychosocial interventions. Down syndrome
population could be a target for investigation
of preventive and therapeutic measures in
management of Alzheimer’s diseasе. World
Heаlth Organisation called for inclusion of
intellectual disability in national dementia
plans., Odrasle osobe sa Daunovim sindromom su u velikom riziku za razvoj Alchajmerove bolesti ranog početka. Demenciji prethodi period prodromalne, pre-kliničke faze. Histopatološki nalazi karakteristični za Alchajmerovu bolest su gotovo pravilo kod osoba sa Daunovim sindromom u petoj deceniji života. Trajektorije kognitivnog propadanja kod populacije sa Daunovim sindromom nisu u potpunosti definisane. Budući da kod ovih osoba već postoji intelektu- alna ometenost, suptilni rani znaci kognitivnog pada se mogu prevideti ili pogrešno dijagnostikovati čime se propušta prilika za pravovremenu pri- menu farmakoloških i psihosocijalnih intervencija. Populacija sa Daunovim sindromom bi mogla biti ciljna za ispitivanje preventivnih i terapijski mera za nastanak Alchajmerove bolesti. Iz ovih razloga, Svetska zdravstvena organizacija je pozvala na uključivanje intelektualne ometenosti u nacional- ne planove za demenciju.",
publisher = "Univerzitet u Beogradu - Fakultet za specijalnu edukaciju i rehabilitaciju",
journal = "Nacionalni naučni skup „Evaluacija efekata inkluzivnog obrazovanja u republici Srbiji” - Zbornik radova",
title = "intelektualna ometenost i razvoj demencije: demencija kod osoba sa daunovim sindromom, Intellectual disability and development of dementia: dementia in persons with down syndrome",
pages = "223-217",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_3467"
}

Pavlović, A.,& Pavlović, D.. (2020). intelektualna ometenost i razvoj demencije: demencija kod osoba sa daunovim sindromom. in Nacionalni naučni skup „Evaluacija efekata inkluzivnog obrazovanja u republici Srbiji” - Zbornik radova
Univerzitet u Beogradu - Fakultet za specijalnu edukaciju i rehabilitaciju., 217-223.
https://hdl.handle.net/21.15107/rcub_rfasper_3467

Pavlović A, Pavlović D. intelektualna ometenost i razvoj demencije: demencija kod osoba sa daunovim sindromom. in Nacionalni naučni skup „Evaluacija efekata inkluzivnog obrazovanja u republici Srbiji” - Zbornik radova. 2020;:217-223.
https://hdl.handle.net/21.15107/rcub_rfasper_3467 .

Pavlović, Aleksandra, Pavlović, Dragan, "intelektualna ometenost i razvoj demencije: demencija kod osoba sa daunovim sindromom" in Nacionalni naučni skup „Evaluacija efekata inkluzivnog obrazovanja u republici Srbiji” - Zbornik radova (2020):217-223,
https://hdl.handle.net/21.15107/rcub_rfasper_3467 .

TY  - BOOK
AU  - Pavlović, Aleksandra
AU  - Pavlović, Dragan
PY  - 2020
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/3303
PB  - OrionArt
T1  - Omega 3 masne kiseline i zdravlje
SP  - 195
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_3303
ER  - 

@book{
author = "Pavlović, Aleksandra and Pavlović, Dragan",
year = "2020",
publisher = "OrionArt",
title = "Omega 3 masne kiseline i zdravlje",
pages = "195",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_3303"
}

Pavlović, A.,& Pavlović, D.. (2020). Omega 3 masne kiseline i zdravlje. 
OrionArt., 195.
https://hdl.handle.net/21.15107/rcub_rfasper_3303

Pavlović A, Pavlović D. Omega 3 masne kiseline i zdravlje. 2020;:195.
https://hdl.handle.net/21.15107/rcub_rfasper_3303 .

Pavlović, Aleksandra, Pavlović, Dragan, "Omega 3 masne kiseline i zdravlje" (2020):195,
https://hdl.handle.net/21.15107/rcub_rfasper_3303 .

TY  - JOUR
AU  - Pavlović, Dragan
AU  - Pavlović, Aleksandra M.
AU  - Đordević, Jelena
PY  - 2020
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/1302
AB  - Omega 3 fatty acids are long-chain polyunsaturated fatty acids (LC-PUFAs). The basic molecule is the Alpha-linolenic acid (ALA) from which LC-PUFAs are formed: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). DHA is the predominant fatty acid in the brain especially in synaptic membranes, astrocytes, myelin and organelle membranes. LC-PUFAs lead to increased membrane fluidity and permeability, and most of the positive effects depend on immunomodulatory activities, via mechanisms of gene expression, cell signaling, and membrane organization. Previous studies in animal models have shown that LC-PUFAs are essential for normal dopaminergic, glutamatergic and serotonergic neurotransmission. Preclinical and clinical studies have demonstrated the role of PUFAs as an effective adjuvant therapy for unipolar and bipolar depression. Lack of omega 3 fatty acids plays a role in the onset of anxiety and aggression. Low omega 3 fatty acids in the prefrontal cortex of people with schizophrenia reduce dopaminergic neurotransmission, contributing to negative and neurocognitive symptoms, while subsequent disinhibition in the limbic system causes positive symptoms. Some evidence suggests that LC-PUFA may delay or even prevent the progression of particular psychotic disorders in high-risk children and adolescents. Epidemiological studies have shown a positive correlation between the relatively high intake of DHA and EPA and the lower relative risk of mild cognitive impairment and dementia or their progression. The recommended daily intake of EPA and DHA varies significantly: 300-500 mg/day as recommended by the World Health Organization (WHO), up to 1-2 grams/day in Norway. Daily intakes of EPA and DHA up to 3 grams are generally recognized as safe. EPA and DHA at doses greater than 3 grams per day can have side effects: an increase in bleeding frequency, oxidation of n-3PUFAs with the formation of biologically active oxidation products, and more.
AB  - Omega 3 masne kiseline su polinezasićene masne kiseline dugih lanaca (LC-PUFAs). Osnovni molekul je alfa-linolenska kiselina (ALA) od koje nastaju LC-PUFA: eikosapentaenoična kiselina (EPA) i dokosaheksaenoička kiselina (DHA). DHA je dominantna masna kiselina u mozgu naročito u sinaptičkim membranama, astrocitima, mijelinu i membranama organela. LC-PUFAs dovode do povećane fluidnosti i permeabilnosti membrana, a većina pozitivnih efekata zavisi od imunomodulacionih aktivnosti, preko mehanizama ekspresije gena, ćelijske signalizacije i organizacije membrane. Dosadašnjim istrazivanjima na animalnim modelima pokazano je da su LC-PUFAs neophodne za normalnu dopaminergičku, glutamatergičku i serotonergičku neurotransmisiju. Prekliničke i kliničke studije su pokazale ulogu PUFAs kao efikasne adjuvantne terapije unipolarne i bipolarne depresije. Nedostatak omega 3 masnih kiselina ima ulogu u nastanku anksioznosti i agresivnosti. Niske omega 3 masne kiseline u prefrontalnoj kori mozga u osoba sa shizofrenijom smanjuju dopaminergičku neurotransmisiju, doprinoseći negativnim i neurokognitivnim simptomima dok posledična dezinhibicija u limbičkom sistemu izaziva pozitivne simptome. Neki dokazi ukazuju da LC-PUFA može da odloži ili čak spreči napredovanje pojedinih psihotičnih poremećaja u visoko rizične dece i adolescenata. Epidemiološke studije su pokazale pozitivnu korelaciju između relativno visokog unosa DHA i EPA i nižeg relativnog rizika od pojave blagog kognitivnog poremećaja i demencije ili njihovog napredovanja. Preporučeni dnevni unos EPA i DHA značajno varira: 300-500 mg/dan kako Svetska zdravstvena organizacija (SZO) preporučuje, pa sve do 1-2 grama/dan u Norveškoj. Dnevni unos EPA i DHA do 3 grama je generalno priznat kao siguran. EPA i DHA u dozama većim od 3 grama dnevno može da da neželjene efekte: povećanje učestalosti krvarenja, oksidaciju n-3PUFAs sa nastankom biološki aktivnih oksidacionih produkata i drugo.
PB  - Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd
T2  - Engrami
T1  - Omega 3 masne kiseline u psihijatriji - mit i stvarnost
T1  - Omega 3 fatty acids in psychiatry: Myth and reality
EP  - 57
IS  - 1
SP  - 44
VL  - 42
DO  - 10.5937/engrami2001044P
ER  - 

@article{
author = "Pavlović, Dragan and Pavlović, Aleksandra M. and Đordević, Jelena",
year = "2020",
abstract = "Omega 3 fatty acids are long-chain polyunsaturated fatty acids (LC-PUFAs). The basic molecule is the Alpha-linolenic acid (ALA) from which LC-PUFAs are formed: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). DHA is the predominant fatty acid in the brain especially in synaptic membranes, astrocytes, myelin and organelle membranes. LC-PUFAs lead to increased membrane fluidity and permeability, and most of the positive effects depend on immunomodulatory activities, via mechanisms of gene expression, cell signaling, and membrane organization. Previous studies in animal models have shown that LC-PUFAs are essential for normal dopaminergic, glutamatergic and serotonergic neurotransmission. Preclinical and clinical studies have demonstrated the role of PUFAs as an effective adjuvant therapy for unipolar and bipolar depression. Lack of omega 3 fatty acids plays a role in the onset of anxiety and aggression. Low omega 3 fatty acids in the prefrontal cortex of people with schizophrenia reduce dopaminergic neurotransmission, contributing to negative and neurocognitive symptoms, while subsequent disinhibition in the limbic system causes positive symptoms. Some evidence suggests that LC-PUFA may delay or even prevent the progression of particular psychotic disorders in high-risk children and adolescents. Epidemiological studies have shown a positive correlation between the relatively high intake of DHA and EPA and the lower relative risk of mild cognitive impairment and dementia or their progression. The recommended daily intake of EPA and DHA varies significantly: 300-500 mg/day as recommended by the World Health Organization (WHO), up to 1-2 grams/day in Norway. Daily intakes of EPA and DHA up to 3 grams are generally recognized as safe. EPA and DHA at doses greater than 3 grams per day can have side effects: an increase in bleeding frequency, oxidation of n-3PUFAs with the formation of biologically active oxidation products, and more., Omega 3 masne kiseline su polinezasićene masne kiseline dugih lanaca (LC-PUFAs). Osnovni molekul je alfa-linolenska kiselina (ALA) od koje nastaju LC-PUFA: eikosapentaenoična kiselina (EPA) i dokosaheksaenoička kiselina (DHA). DHA je dominantna masna kiselina u mozgu naročito u sinaptičkim membranama, astrocitima, mijelinu i membranama organela. LC-PUFAs dovode do povećane fluidnosti i permeabilnosti membrana, a većina pozitivnih efekata zavisi od imunomodulacionih aktivnosti, preko mehanizama ekspresije gena, ćelijske signalizacije i organizacije membrane. Dosadašnjim istrazivanjima na animalnim modelima pokazano je da su LC-PUFAs neophodne za normalnu dopaminergičku, glutamatergičku i serotonergičku neurotransmisiju. Prekliničke i kliničke studije su pokazale ulogu PUFAs kao efikasne adjuvantne terapije unipolarne i bipolarne depresije. Nedostatak omega 3 masnih kiselina ima ulogu u nastanku anksioznosti i agresivnosti. Niske omega 3 masne kiseline u prefrontalnoj kori mozga u osoba sa shizofrenijom smanjuju dopaminergičku neurotransmisiju, doprinoseći negativnim i neurokognitivnim simptomima dok posledična dezinhibicija u limbičkom sistemu izaziva pozitivne simptome. Neki dokazi ukazuju da LC-PUFA može da odloži ili čak spreči napredovanje pojedinih psihotičnih poremećaja u visoko rizične dece i adolescenata. Epidemiološke studije su pokazale pozitivnu korelaciju između relativno visokog unosa DHA i EPA i nižeg relativnog rizika od pojave blagog kognitivnog poremećaja i demencije ili njihovog napredovanja. Preporučeni dnevni unos EPA i DHA značajno varira: 300-500 mg/dan kako Svetska zdravstvena organizacija (SZO) preporučuje, pa sve do 1-2 grama/dan u Norveškoj. Dnevni unos EPA i DHA do 3 grama je generalno priznat kao siguran. EPA i DHA u dozama većim od 3 grama dnevno može da da neželjene efekte: povećanje učestalosti krvarenja, oksidaciju n-3PUFAs sa nastankom biološki aktivnih oksidacionih produkata i drugo.",
publisher = "Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd",
journal = "Engrami",
title = "Omega 3 masne kiseline u psihijatriji - mit i stvarnost, Omega 3 fatty acids in psychiatry: Myth and reality",
pages = "57-44",
number = "1",
volume = "42",
doi = "10.5937/engrami2001044P"
}

Pavlović, D., Pavlović, A. M.,& Đordević, J.. (2020). Omega 3 masne kiseline u psihijatriji - mit i stvarnost. in Engrami
Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd., 42(1), 44-57.
https://doi.org/10.5937/engrami2001044P

Pavlović D, Pavlović AM, Đordević J. Omega 3 masne kiseline u psihijatriji - mit i stvarnost. in Engrami. 2020;42(1):44-57.
doi:10.5937/engrami2001044P .

Pavlović, Dragan, Pavlović, Aleksandra M., Đordević, Jelena, "Omega 3 masne kiseline u psihijatriji - mit i stvarnost" in Engrami, 42, no. 1 (2020):44-57,
https://doi.org/10.5937/engrami2001044P . .

TY  - JOUR
AU  - Vuković, Mile
AU  - Jašarević, Aneta
AU  - Pavlović, Dragan
AU  - Prica-Obradović, Nada
PY  - 2020
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/1297
AB  - Introduction Although clinical practice shows that children with spastic cerebral palsy have disturbances in the development of speech and language, literature is very scarce with data in this area. In particular, it is missing data on the specificities of speech-language disorders and the mobility of speech organs. Objective the aim of this paper is to assess the development of speech and language abilities and to determine the characteristics of speech disorders in children with spastic cerebral palsy. We were also interested in the state of mobility of speech organs in this category of children. Method the sample consisted of 10 respondents (6 boys and 4 girls), aged four years, with spastic cerebral palsy who were treated at the Special hospital for cerebral palsy and developmental neurology in Belgrade. Based on the medical documentation and the results of testing, the course of language development, speech-language abnormalities and mobility of speech organs were analysed. The Test for the articulation assessment and the Test for voice assessment were applicable, while the prosodic features of speech were assessed by perceptual analysis of recorded speech patterns. The mobility of speech organs was assessed by clinical observation and by using a Test of voluntary oral motor activity. Results the results showed that children with spastic cerebral palsy have a significant delay in speech and language development. They master the elements of the linguistic structure much later than the typically developing children. Most children with spastic cerebral palsy have dysarthria characterized by difficulties in the articulation of the consonants, the change in voice quality, and disturbance of rhythm and rate of speech. Disturbances in speech are accompanied by slow movements of speech organs. Conclusion Children with spastic cerebral palsy are late in the development of speech-language abilities, they have a disorder of articulation of consonants, altered voice quality and impairment of the prosodic features of speech.
AB  - Uvod Iako klinička praksa pokazuje da deca sa spastičnom cerebralnom paralizom ispoljavaju poremećaje u razvoju govora i jezika, literatura je veoma oskudna podacima u ovoj oblasti. Posebno nedostaju podaci o specifičnostima govorno-jezičkih poremećaja i pokretljivosti govornih organa. Cilj ovog rada jeste procena razvoja govorno-jezičkih sposobnosti i utvrđivanje karakteritika poremećaja govora kod dece sa spastičnom cerebralnom paralizom. Takođe nas je zanimalo stanje pokretljivosti govornih organa u ovoj populaciji Metod Uzorak je činilo 10 ispitanika (6 dečaka i 4 devojčice) sa spastičnom cerebralnom paralizom uzrasta od četiri godine, koja su lečena u Specijalnoj bolnici za cerebralnu paralizu i razvojnu neurologiju u Beogradu. Na osnovu uvida u logopedsku dokumentaciju i testiranja, analizirani su tok jezičkog razvoja, poremećaji govorno-jezičkih sposobnosti i pokretljivost govornih organa. Primenjeni su Trijažni artikulacioni test, Test za ispitivanje osnovnog laringealnog glasa, dok su prozodijska obeležja i razumljivost govora procenjeni na osnovu preceptivne analize snimljenih uzoraka govora. Pokretljivost govornih organa procenjena je kliničkom opservacijom, a voljna motorna aktivnost Testom oralne praksije. Rezultati su pokazali da deca sa spastičnom cerebralnom paralizom znatno kasnije progovaraju i ovladavaju elementima jezičke strukture u odnosu na decu tipičnog razvoja. Kod većine dece identifikovana je dizartrija koju karakterišu teškoće u artikulaciji konsonanata, promene kvaliteta glasa i poremećaj ritma i tempa govora. Poremećaji u govoru praćeni su usporenim pokretima govornih organa. Zaključak Deca sa spastičnom cerebralnom paralizom kasne u razvoju govorno-jezičkih sposobnosti, imaju poremećaj artikulacije glasova, izmenjen kvalitet glasa i oštećenje prozodijskih obeležja govora.
PB  - Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd
T2  - Engrami
T1  - Govorno-jezičke sposobnosti i pokretljivost govornih organa kod dece sa spastičnom cerebralnom paralizom - preliminarno ispitivanje
T1  - Speech and language abilities and oral-motor movability in children with spastic cerebral palsy: Preliminary research
EP  - 19
IS  - 1
SP  - 6
VL  - 42
DO  - 10.5937/engrami2001006V
ER  - 

@article{
author = "Vuković, Mile and Jašarević, Aneta and Pavlović, Dragan and Prica-Obradović, Nada",
year = "2020",
abstract = "Introduction Although clinical practice shows that children with spastic cerebral palsy have disturbances in the development of speech and language, literature is very scarce with data in this area. In particular, it is missing data on the specificities of speech-language disorders and the mobility of speech organs. Objective the aim of this paper is to assess the development of speech and language abilities and to determine the characteristics of speech disorders in children with spastic cerebral palsy. We were also interested in the state of mobility of speech organs in this category of children. Method the sample consisted of 10 respondents (6 boys and 4 girls), aged four years, with spastic cerebral palsy who were treated at the Special hospital for cerebral palsy and developmental neurology in Belgrade. Based on the medical documentation and the results of testing, the course of language development, speech-language abnormalities and mobility of speech organs were analysed. The Test for the articulation assessment and the Test for voice assessment were applicable, while the prosodic features of speech were assessed by perceptual analysis of recorded speech patterns. The mobility of speech organs was assessed by clinical observation and by using a Test of voluntary oral motor activity. Results the results showed that children with spastic cerebral palsy have a significant delay in speech and language development. They master the elements of the linguistic structure much later than the typically developing children. Most children with spastic cerebral palsy have dysarthria characterized by difficulties in the articulation of the consonants, the change in voice quality, and disturbance of rhythm and rate of speech. Disturbances in speech are accompanied by slow movements of speech organs. Conclusion Children with spastic cerebral palsy are late in the development of speech-language abilities, they have a disorder of articulation of consonants, altered voice quality and impairment of the prosodic features of speech., Uvod Iako klinička praksa pokazuje da deca sa spastičnom cerebralnom paralizom ispoljavaju poremećaje u razvoju govora i jezika, literatura je veoma oskudna podacima u ovoj oblasti. Posebno nedostaju podaci o specifičnostima govorno-jezičkih poremećaja i pokretljivosti govornih organa. Cilj ovog rada jeste procena razvoja govorno-jezičkih sposobnosti i utvrđivanje karakteritika poremećaja govora kod dece sa spastičnom cerebralnom paralizom. Takođe nas je zanimalo stanje pokretljivosti govornih organa u ovoj populaciji Metod Uzorak je činilo 10 ispitanika (6 dečaka i 4 devojčice) sa spastičnom cerebralnom paralizom uzrasta od četiri godine, koja su lečena u Specijalnoj bolnici za cerebralnu paralizu i razvojnu neurologiju u Beogradu. Na osnovu uvida u logopedsku dokumentaciju i testiranja, analizirani su tok jezičkog razvoja, poremećaji govorno-jezičkih sposobnosti i pokretljivost govornih organa. Primenjeni su Trijažni artikulacioni test, Test za ispitivanje osnovnog laringealnog glasa, dok su prozodijska obeležja i razumljivost govora procenjeni na osnovu preceptivne analize snimljenih uzoraka govora. Pokretljivost govornih organa procenjena je kliničkom opservacijom, a voljna motorna aktivnost Testom oralne praksije. Rezultati su pokazali da deca sa spastičnom cerebralnom paralizom znatno kasnije progovaraju i ovladavaju elementima jezičke strukture u odnosu na decu tipičnog razvoja. Kod većine dece identifikovana je dizartrija koju karakterišu teškoće u artikulaciji konsonanata, promene kvaliteta glasa i poremećaj ritma i tempa govora. Poremećaji u govoru praćeni su usporenim pokretima govornih organa. Zaključak Deca sa spastičnom cerebralnom paralizom kasne u razvoju govorno-jezičkih sposobnosti, imaju poremećaj artikulacije glasova, izmenjen kvalitet glasa i oštećenje prozodijskih obeležja govora.",
publisher = "Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd",
journal = "Engrami",
title = "Govorno-jezičke sposobnosti i pokretljivost govornih organa kod dece sa spastičnom cerebralnom paralizom - preliminarno ispitivanje, Speech and language abilities and oral-motor movability in children with spastic cerebral palsy: Preliminary research",
pages = "19-6",
number = "1",
volume = "42",
doi = "10.5937/engrami2001006V"
}

Vuković, M., Jašarević, A., Pavlović, D.,& Prica-Obradović, N.. (2020). Govorno-jezičke sposobnosti i pokretljivost govornih organa kod dece sa spastičnom cerebralnom paralizom - preliminarno ispitivanje. in Engrami
Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd., 42(1), 6-19.
https://doi.org/10.5937/engrami2001006V

Vuković M, Jašarević A, Pavlović D, Prica-Obradović N. Govorno-jezičke sposobnosti i pokretljivost govornih organa kod dece sa spastičnom cerebralnom paralizom - preliminarno ispitivanje. in Engrami. 2020;42(1):6-19.
doi:10.5937/engrami2001006V .

Vuković, Mile, Jašarević, Aneta, Pavlović, Dragan, Prica-Obradović, Nada, "Govorno-jezičke sposobnosti i pokretljivost govornih organa kod dece sa spastičnom cerebralnom paralizom - preliminarno ispitivanje" in Engrami, 42, no. 1 (2020):6-19,
https://doi.org/10.5937/engrami2001006V . .

TY  - JOUR
AU  - Todorović, Jelena
AU  - Pavlović, Dragan
AU  - Zelić, Mirna
AU  - Jerkić, Lana
PY  - 2020
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/1307
AB  - Neurofibromatoses are a set of different genetic disorders that have a common characteristic of the appearance of nervous system tumors. There are three forms of the disease, of which type 1 neurofibromatosis (NF 1) is the most common. NF 1 is an inherited autosomal-dominant disease, with a high rate of new mutations. In addition to the many physical manifestations and complications that occur in persons with NF 1, there are also numerous cognitive difficulties, including lower general intellectual functioning, learning difficulties, but also problems in attention, visual abilities, executive functions, and speech. Attention disorders are up to three times more common in people with NF 1, while learning disabilities are present in more than half of these subjects. Disturbances in the field of visuospatial perception are recognisable even in the preschool period. About 80% of children with NF1 exhibit various speech and language disorders: slow early speech development, slower vocabulary enrichment, syntactic, semantic and phonological speech disorders. Disruption of executive functions will manifest itself in the areas of working memory, organisation, planning / problem solving. This will reflect as the underperformance in academic achievement. Nearly one-third of these persons have emotional and social problems.
AB  - Neurofibromatoze su skup različitih genetskih poremećaja kojima je zajednička karakteristika pojava tumora nervnog sistema. Razlikuju se tri oblika bolesti, od kojih je neurofibromatoza tip 1 (NF 1) najčešća. Nasleđuje se autozomno-dominantno, sa visokom stopom novih mutacija. Pored brojnih fizičkih manifestacija i komplikacija koje se ispoljavaju kod osoba sa NF 1, prisutne su i brojne kognitivne teškoće, uključujući i opšte intelektualno funkcionisanje, smetnje učenja, ali i problemi na nivou pažnje, vizuo-spacijalnih sposobnosti, egzekutivnih funkcija, pa i govora. Poremećaj pažnje je i do tri puta češći kod osoba sa NF 1, dok su smetnje u učenju prisutne kod više od polovine ovih osoba. Poremećaji na planu vizuospacijalne percepcije su prepoznatljivi još u predškolskom periodu. Oko 80% dece s NF 1 pokazuje različite poremećaje govora i jezika - usporen rani razvoj govora, sporije obogaćivanje rečnika, sintaksičke, semantičke i fonološke poremećaje govora. Poremećaj egzekutivnih funkcija će se ispoljiti na planu radne memorije, organizacije, planiranja/ rešavanja problema. Ovo će se odraziti na na slabija postignuća u akademskom obrazovanju. Skoro jedna trećina osoba sa NF 1 ima emocionalne i socijalne probleme.
PB  - Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd
T2  - Engrami
T1  - Kognitivni fenotip kod neurofibromatoze tip 1
T1  - Cognitive phenotype in neurofibromatosis type 1
EP  - 79
IS  - 2
SP  - 69
VL  - 42
DO  - 10.5937/engrami41-28271
ER  - 

@article{
author = "Todorović, Jelena and Pavlović, Dragan and Zelić, Mirna and Jerkić, Lana",
year = "2020",
abstract = "Neurofibromatoses are a set of different genetic disorders that have a common characteristic of the appearance of nervous system tumors. There are three forms of the disease, of which type 1 neurofibromatosis (NF 1) is the most common. NF 1 is an inherited autosomal-dominant disease, with a high rate of new mutations. In addition to the many physical manifestations and complications that occur in persons with NF 1, there are also numerous cognitive difficulties, including lower general intellectual functioning, learning difficulties, but also problems in attention, visual abilities, executive functions, and speech. Attention disorders are up to three times more common in people with NF 1, while learning disabilities are present in more than half of these subjects. Disturbances in the field of visuospatial perception are recognisable even in the preschool period. About 80% of children with NF1 exhibit various speech and language disorders: slow early speech development, slower vocabulary enrichment, syntactic, semantic and phonological speech disorders. Disruption of executive functions will manifest itself in the areas of working memory, organisation, planning / problem solving. This will reflect as the underperformance in academic achievement. Nearly one-third of these persons have emotional and social problems., Neurofibromatoze su skup različitih genetskih poremećaja kojima je zajednička karakteristika pojava tumora nervnog sistema. Razlikuju se tri oblika bolesti, od kojih je neurofibromatoza tip 1 (NF 1) najčešća. Nasleđuje se autozomno-dominantno, sa visokom stopom novih mutacija. Pored brojnih fizičkih manifestacija i komplikacija koje se ispoljavaju kod osoba sa NF 1, prisutne su i brojne kognitivne teškoće, uključujući i opšte intelektualno funkcionisanje, smetnje učenja, ali i problemi na nivou pažnje, vizuo-spacijalnih sposobnosti, egzekutivnih funkcija, pa i govora. Poremećaj pažnje je i do tri puta češći kod osoba sa NF 1, dok su smetnje u učenju prisutne kod više od polovine ovih osoba. Poremećaji na planu vizuospacijalne percepcije su prepoznatljivi još u predškolskom periodu. Oko 80% dece s NF 1 pokazuje različite poremećaje govora i jezika - usporen rani razvoj govora, sporije obogaćivanje rečnika, sintaksičke, semantičke i fonološke poremećaje govora. Poremećaj egzekutivnih funkcija će se ispoljiti na planu radne memorije, organizacije, planiranja/ rešavanja problema. Ovo će se odraziti na na slabija postignuća u akademskom obrazovanju. Skoro jedna trećina osoba sa NF 1 ima emocionalne i socijalne probleme.",
publisher = "Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd",
journal = "Engrami",
title = "Kognitivni fenotip kod neurofibromatoze tip 1, Cognitive phenotype in neurofibromatosis type 1",
pages = "79-69",
number = "2",
volume = "42",
doi = "10.5937/engrami41-28271"
}

Todorović, J., Pavlović, D., Zelić, M.,& Jerkić, L.. (2020). Kognitivni fenotip kod neurofibromatoze tip 1. in Engrami
Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd., 42(2), 69-79.
https://doi.org/10.5937/engrami41-28271

Todorović J, Pavlović D, Zelić M, Jerkić L. Kognitivni fenotip kod neurofibromatoze tip 1. in Engrami. 2020;42(2):69-79.
doi:10.5937/engrami41-28271 .

Todorović, Jelena, Pavlović, Dragan, Zelić, Mirna, Jerkić, Lana, "Kognitivni fenotip kod neurofibromatoze tip 1" in Engrami, 42, no. 2 (2020):69-79,
https://doi.org/10.5937/engrami41-28271 . .

TY  - JOUR
AU  - Jerkić, Lana
AU  - Pavlović, Dragan
AU  - Vuković, Mile
AU  - Todorović, Jelena
AU  - Zelić, Mirna
PY  - 2020
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/1292
AB  - Primary progressive aphasia (PPA) includes a group of neurodegenerative disorders that are characterized by progressive deterioration of language functions, while other cognitive functions, at least at the onset of the disease, are relatively spared. There are three basic subtypes of PPA: the nonfluent progressive aphasia (nvPPA), the semantic variant of a primary progressive aphasia (svPPA), and the logopenic progressive aphasia (lvPPA). The semantic variant of a PPA can also be found in the literature under the term of semantic dementia. It is clinically manifested by progressive deterioration of semantic knowledge, fluent aphasia, impaired naming and comprehension, prosopagnosia and surface dyslexia and dysgraphia (in languages with irregular orthography). As the disease progresses, other cognitive changes can be observed. The main cause of the disorder is progressive bilateral atrophy of the anterior temporal lobes, which is more manifested in the left hemisphere. The literature is modest in terms of the use of specific treatment methods in the rehabilitation of these patients. Since speech and language disorders are the most conspicuous symptom, at least at the beginning of the disease, the role of speech therapists in the assessment and restitution of speechlanguage and communication skills is also indisputable.
AB  - Primarna progresivna afazija (PPA) obuhvata grupu neurodegenerativnih poremećaja, koje karakteriše progresivno propadanje jezičkih funkcija, dok su druge kognitivne funkcije, barem na početku bolesti, relativno pošteđene. Izdvojene su tri osnovne varijante PPA: nefluentna progresivna afazija (nvPPA), semantička varijanta primarne progresivne afazije (svPPA) i logopenična progresivna afazija (lvPPA). Semantička varijanta PPA može se pronaći u literaturi i pod nazivom semantička demencija. Klinički se ispoljava progresivnim propadanjem semantičkog znanja, fluentnom afazijom, oštećenim imenovanjem i razumevanjem, prozopagnozijom i površinskom disleksijom i disgrafijom (u jezicima s nepravilnom ortografijom). S progresijom bolesti, uočavaju se i druge promene na kognitivnom planu. Osnovni uzrok ove bolesti je progresivna obostrana atrofija prednjih temporalnih režnjeva, koja je izraženija u levoj hemisferi. Nema dovoljno podataka u literaturi o korišćenju specifičnih metoda tretmana u rehabilitaciji ovih bolesnika. S obzirom na to da su govorno-jezički poremećaji najupadljiviji simptom, bar na početku bolesti, nesporna je i uloga logopeda u proceni i restituciji govorno-jezičkih i komunikativnih sposobnosti.
PB  - Srpsko lekarsko društvo - Okružna podružnica Kragujevac, Kragujevac
T2  - Medicinski časopis
T1  - Profile of linguistic and cognitive deficits in persons with a semantic variant of a primary progressive aphasia
T1  - Profil jezičkih i kognitivnih deficita kod osoba sa semantičkom varijantom primarne progresivne afazije
EP  - 119
IS  - 3
SP  - 113
VL  - 54
DO  - 10.5937/mckg54-27796
ER  - 

@article{
author = "Jerkić, Lana and Pavlović, Dragan and Vuković, Mile and Todorović, Jelena and Zelić, Mirna",
year = "2020",
abstract = "Primary progressive aphasia (PPA) includes a group of neurodegenerative disorders that are characterized by progressive deterioration of language functions, while other cognitive functions, at least at the onset of the disease, are relatively spared. There are three basic subtypes of PPA: the nonfluent progressive aphasia (nvPPA), the semantic variant of a primary progressive aphasia (svPPA), and the logopenic progressive aphasia (lvPPA). The semantic variant of a PPA can also be found in the literature under the term of semantic dementia. It is clinically manifested by progressive deterioration of semantic knowledge, fluent aphasia, impaired naming and comprehension, prosopagnosia and surface dyslexia and dysgraphia (in languages with irregular orthography). As the disease progresses, other cognitive changes can be observed. The main cause of the disorder is progressive bilateral atrophy of the anterior temporal lobes, which is more manifested in the left hemisphere. The literature is modest in terms of the use of specific treatment methods in the rehabilitation of these patients. Since speech and language disorders are the most conspicuous symptom, at least at the beginning of the disease, the role of speech therapists in the assessment and restitution of speechlanguage and communication skills is also indisputable., Primarna progresivna afazija (PPA) obuhvata grupu neurodegenerativnih poremećaja, koje karakteriše progresivno propadanje jezičkih funkcija, dok su druge kognitivne funkcije, barem na početku bolesti, relativno pošteđene. Izdvojene su tri osnovne varijante PPA: nefluentna progresivna afazija (nvPPA), semantička varijanta primarne progresivne afazije (svPPA) i logopenična progresivna afazija (lvPPA). Semantička varijanta PPA može se pronaći u literaturi i pod nazivom semantička demencija. Klinički se ispoljava progresivnim propadanjem semantičkog znanja, fluentnom afazijom, oštećenim imenovanjem i razumevanjem, prozopagnozijom i površinskom disleksijom i disgrafijom (u jezicima s nepravilnom ortografijom). S progresijom bolesti, uočavaju se i druge promene na kognitivnom planu. Osnovni uzrok ove bolesti je progresivna obostrana atrofija prednjih temporalnih režnjeva, koja je izraženija u levoj hemisferi. Nema dovoljno podataka u literaturi o korišćenju specifičnih metoda tretmana u rehabilitaciji ovih bolesnika. S obzirom na to da su govorno-jezički poremećaji najupadljiviji simptom, bar na početku bolesti, nesporna je i uloga logopeda u proceni i restituciji govorno-jezičkih i komunikativnih sposobnosti.",
publisher = "Srpsko lekarsko društvo - Okružna podružnica Kragujevac, Kragujevac",
journal = "Medicinski časopis",
title = "Profile of linguistic and cognitive deficits in persons with a semantic variant of a primary progressive aphasia, Profil jezičkih i kognitivnih deficita kod osoba sa semantičkom varijantom primarne progresivne afazije",
pages = "119-113",
number = "3",
volume = "54",
doi = "10.5937/mckg54-27796"
}

Jerkić, L., Pavlović, D., Vuković, M., Todorović, J.,& Zelić, M.. (2020). Profile of linguistic and cognitive deficits in persons with a semantic variant of a primary progressive aphasia. in Medicinski časopis
Srpsko lekarsko društvo - Okružna podružnica Kragujevac, Kragujevac., 54(3), 113-119.
https://doi.org/10.5937/mckg54-27796

Jerkić L, Pavlović D, Vuković M, Todorović J, Zelić M. Profile of linguistic and cognitive deficits in persons with a semantic variant of a primary progressive aphasia. in Medicinski časopis. 2020;54(3):113-119.
doi:10.5937/mckg54-27796 .

Jerkić, Lana, Pavlović, Dragan, Vuković, Mile, Todorović, Jelena, Zelić, Mirna, "Profile of linguistic and cognitive deficits in persons with a semantic variant of a primary progressive aphasia" in Medicinski časopis, 54, no. 3 (2020):113-119,
https://doi.org/10.5937/mckg54-27796 . .

TY  - BOOK
AU  - Pavlović, Dragan
PY  - 2019
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/3094
PB  - OrionArt
T1  - Ortomolekularna neurologija i psihijatrija. Kako poboljšati rad mozga uz pomoć suplemanata/mikronutrijenata
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_3094
ER  - 

@book{
author = "Pavlović, Dragan",
year = "2019",
publisher = "OrionArt",
title = "Ortomolekularna neurologija i psihijatrija. Kako poboljšati rad mozga uz pomoć suplemanata/mikronutrijenata",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_3094"
}

Pavlović, D.. (2019). Ortomolekularna neurologija i psihijatrija. Kako poboljšati rad mozga uz pomoć suplemanata/mikronutrijenata. 
OrionArt..
https://hdl.handle.net/21.15107/rcub_rfasper_3094

Pavlović D. Ortomolekularna neurologija i psihijatrija. Kako poboljšati rad mozga uz pomoć suplemanata/mikronutrijenata. 2019;.
https://hdl.handle.net/21.15107/rcub_rfasper_3094 .

Pavlović, Dragan, "Ortomolekularna neurologija i psihijatrija. Kako poboljšati rad mozga uz pomoć suplemanata/mikronutrijenata" (2019),
https://hdl.handle.net/21.15107/rcub_rfasper_3094 .

TY  - JOUR
AU  - Lukovac, Tanja
AU  - Pavlović, Dragan
PY  - 2019
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/1182
AB  - Attention Deficit Hyperactivity Disorder (ADHD) is a clinical behavioral disorder in children marked by an ongoing pattern of inattention and/or hyperactivity-impulsivity in all situations, which occurs early and persists through time. The aim of the paper is to review the previous scientific studies in which the issue of association between the attention deficit and hyperactivity and micronutrients (vitamins and minerals) was addressed, by examining the available literature. Numerous studies have correlated the diet, that is, nutritional deficits with the ADHD. Deficiency of fatty acids, as well as the lack of zinc and iron, were the most frequently observed. Some studies have reported a significant effect of precisely defined doses of vitamins D and B12, while others have determined the existence of a positive correlation between the severity of ADHD symptoms and the level of nutritional deficiency. Overall, the duction of appropriate nutritional and/ or supplementation regimens could be a good option for reducing the ADHD symptoms. As a practical contribution, all information on possible unwanted outcomes of micronutrient imbalance should be available to parents of children with ADHD and experts directly involved in working with these families. Larger studies are needed to determine the optimal multifactorial treatment that includes, in addition to medications and behavioral work, balanced nutrition with the necessary supplementation.
AB  - Poremećaj pažnje sa hiperaktivnošću (eng. Attention Deficit Hyperactivity Disorder - ADHD) je klinički poremećaj ponašanja kod dece kod koga se javlja nedostatak pažnje i/ili hiperaktivnost u svim situacijama, a koji se javlјa rano i perzistira kroz vreme. Cilј rada je da se uvidom u dostupnu literaturu, napravi pregled dosadašnjih naučnih radova u kojima je obrađivana problematika povezanosti deficita pažnje i hiperaktivnosti i mikronutrijenata: vitamina i minerala. Brojne studije dovele su u vezu ishranu, odnosno, nutricione deficite sa nastankom ADHD. Najčešće su uočeni deficiti masnih kiselina, kao i nedostatak cinka i gvožđa. Neke studije su izvestile o značajnom učinku precizno određenih doza vitamin D i B12, dok su druge utvrdile postojanje pozitivne korelacije između jačine ADHD simptoma i nivoa nutritivnog deficita. Sveukupno, uvođenje odgovarajućih režima ishrane i/ili suplementacije bi mogla biti dobra opcija za smanjenje simptoma ADHD. Kao praktični doprinos, potrebno je da sve informacije o mogućim neželјenim ishodima disbalansa mikronutrijenata budu dostupne roditelјima dece sa ADHD i stručnjacima neposredno uklјučenim u rad sa ovim porodicama. Potrebne su veće studije za određivanje optimalnog multifaktorskog tretmana koji uklјučuje, pored lekova i bihevioralnog rada, izbalansiranu ishranu sa potrebnom suplementacijom.
PB  - Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd
T2  - Engrami
T1  - Attention deficit hyperactivity disorder and micronutrities
T1  - Poremećaj pažnje sa hiperaktivnošću i mikronutritijenti
EP  - 59
IS  - 1
SP  - 46
VL  - 41
DO  - 10.5937/engrami1901046L
ER  - 

@article{
author = "Lukovac, Tanja and Pavlović, Dragan",
year = "2019",
abstract = "Attention Deficit Hyperactivity Disorder (ADHD) is a clinical behavioral disorder in children marked by an ongoing pattern of inattention and/or hyperactivity-impulsivity in all situations, which occurs early and persists through time. The aim of the paper is to review the previous scientific studies in which the issue of association between the attention deficit and hyperactivity and micronutrients (vitamins and minerals) was addressed, by examining the available literature. Numerous studies have correlated the diet, that is, nutritional deficits with the ADHD. Deficiency of fatty acids, as well as the lack of zinc and iron, were the most frequently observed. Some studies have reported a significant effect of precisely defined doses of vitamins D and B12, while others have determined the existence of a positive correlation between the severity of ADHD symptoms and the level of nutritional deficiency. Overall, the duction of appropriate nutritional and/ or supplementation regimens could be a good option for reducing the ADHD symptoms. As a practical contribution, all information on possible unwanted outcomes of micronutrient imbalance should be available to parents of children with ADHD and experts directly involved in working with these families. Larger studies are needed to determine the optimal multifactorial treatment that includes, in addition to medications and behavioral work, balanced nutrition with the necessary supplementation., Poremećaj pažnje sa hiperaktivnošću (eng. Attention Deficit Hyperactivity Disorder - ADHD) je klinički poremećaj ponašanja kod dece kod koga se javlja nedostatak pažnje i/ili hiperaktivnost u svim situacijama, a koji se javlјa rano i perzistira kroz vreme. Cilј rada je da se uvidom u dostupnu literaturu, napravi pregled dosadašnjih naučnih radova u kojima je obrađivana problematika povezanosti deficita pažnje i hiperaktivnosti i mikronutrijenata: vitamina i minerala. Brojne studije dovele su u vezu ishranu, odnosno, nutricione deficite sa nastankom ADHD. Najčešće su uočeni deficiti masnih kiselina, kao i nedostatak cinka i gvožđa. Neke studije su izvestile o značajnom učinku precizno određenih doza vitamin D i B12, dok su druge utvrdile postojanje pozitivne korelacije između jačine ADHD simptoma i nivoa nutritivnog deficita. Sveukupno, uvođenje odgovarajućih režima ishrane i/ili suplementacije bi mogla biti dobra opcija za smanjenje simptoma ADHD. Kao praktični doprinos, potrebno je da sve informacije o mogućim neželјenim ishodima disbalansa mikronutrijenata budu dostupne roditelјima dece sa ADHD i stručnjacima neposredno uklјučenim u rad sa ovim porodicama. Potrebne su veće studije za određivanje optimalnog multifaktorskog tretmana koji uklјučuje, pored lekova i bihevioralnog rada, izbalansiranu ishranu sa potrebnom suplementacijom.",
publisher = "Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd",
journal = "Engrami",
title = "Attention deficit hyperactivity disorder and micronutrities, Poremećaj pažnje sa hiperaktivnošću i mikronutritijenti",
pages = "59-46",
number = "1",
volume = "41",
doi = "10.5937/engrami1901046L"
}

Lukovac, T.,& Pavlović, D.. (2019). Attention deficit hyperactivity disorder and micronutrities. in Engrami
Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd., 41(1), 46-59.
https://doi.org/10.5937/engrami1901046L

Lukovac T, Pavlović D. Attention deficit hyperactivity disorder and micronutrities. in Engrami. 2019;41(1):46-59.
doi:10.5937/engrami1901046L .

Lukovac, Tanja, Pavlović, Dragan, "Attention deficit hyperactivity disorder and micronutrities" in Engrami, 41, no. 1 (2019):46-59,
https://doi.org/10.5937/engrami1901046L . .

TY  - JOUR
AU  - Pavlović, Dragan
AU  - Pekić, Sandra
AU  - Stojanović, Marko
AU  - Popović, Vera
PY  - 2019
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/1208
AB  - Traumatic brain injury (TBI) causes substantial neurological disabilities and mental distress. Annual TBI incidence is in magnitude of millions, making it a global health challenge. Categorization of TBI into severe, moderate and mild by scores on the Glasgow coma scale (GCS) is based on clinical grounds and standard brain imaging (CT). Recent research focusedon repeated mild TBI (sport and non-sport concussions) suggests that a considerable number of patients have long-term disabling neurocognitive and neurobehavioral sequelae. These relate to subtle neuronal injury (diffuse axonal injury) visible only by using advanced neuroimaging distinguishing microstructural tissue damage. With advanced MRI protocols better characterization of TBI is achievable. Diffusion tensor imaging (DTI) visualizes white matter pathology, susceptibility weight imaging (SWI) detects microscopic bleeding while functional magnetic resonance imaging (fMRI) provides closer understanding of cognitive disorders etc. However, advanced imaging is still not integrated in the clinical care of patients with TBI. Patients with chronic TBI may experience many somatic disorders, cognitive disturbances and mental complaints. The underlying pathophysiological mechanisms occurring in TBI are complex, brain injuries are highly heterogeneous and include neuroendocrine dysfunctions. Post-traumatic neuroendocrine dysfunctions received attention since the year 2000. Occurrence of TBI-related hypopituitarism does not correlate to severity of the GCS scores. Complete or partial hypopituitarism (isolated growth hormone (GH) deficiency as most frequent) may occur after mild TBI equally as after moderate-to-severe TBI. Many symptoms of hypopituitarism overlap with symptoms occurring in patients with chronic TBI, i.e. they have lower scores on neuropsychological examinations (cognitive disability) and have more symptoms of mental distress (depression and fatigue). The great challenges for the endocrinologist are: (1) detection of hypopituitarism in patients with TBI prospectively (in the acute phase and months to years after TBI), (2) assessment of the extent of cognitive impairment at baseline, and (3) monitoring of treatment effects (alteration of cognitive functioning and mental distress with hormone replacement therapy). Only few studies recently suggest that with growth hormone (rhGH) replacement in patients with chronic TBI and with abnormal GH secretion, cognitive performance may not change while symptoms related to depression and fatigue improve. Stagnation in post-TBI rehabilitation progress is recommended as a signal for clinical suspicion of neuroendocrine dysfunction. This remains a challenging area for more research.
PB  - Springer, New York
T2  - Pituitary
T1  - Traumatic brain injury: neuropathological, neurocognitive and neurobehavioral sequelae
EP  - 282
IS  - 3
SP  - 270
VL  - 22
DO  - 10.1007/s11102-019-00957-9
ER  - 

@article{
author = "Pavlović, Dragan and Pekić, Sandra and Stojanović, Marko and Popović, Vera",
year = "2019",
abstract = "Traumatic brain injury (TBI) causes substantial neurological disabilities and mental distress. Annual TBI incidence is in magnitude of millions, making it a global health challenge. Categorization of TBI into severe, moderate and mild by scores on the Glasgow coma scale (GCS) is based on clinical grounds and standard brain imaging (CT). Recent research focusedon repeated mild TBI (sport and non-sport concussions) suggests that a considerable number of patients have long-term disabling neurocognitive and neurobehavioral sequelae. These relate to subtle neuronal injury (diffuse axonal injury) visible only by using advanced neuroimaging distinguishing microstructural tissue damage. With advanced MRI protocols better characterization of TBI is achievable. Diffusion tensor imaging (DTI) visualizes white matter pathology, susceptibility weight imaging (SWI) detects microscopic bleeding while functional magnetic resonance imaging (fMRI) provides closer understanding of cognitive disorders etc. However, advanced imaging is still not integrated in the clinical care of patients with TBI. Patients with chronic TBI may experience many somatic disorders, cognitive disturbances and mental complaints. The underlying pathophysiological mechanisms occurring in TBI are complex, brain injuries are highly heterogeneous and include neuroendocrine dysfunctions. Post-traumatic neuroendocrine dysfunctions received attention since the year 2000. Occurrence of TBI-related hypopituitarism does not correlate to severity of the GCS scores. Complete or partial hypopituitarism (isolated growth hormone (GH) deficiency as most frequent) may occur after mild TBI equally as after moderate-to-severe TBI. Many symptoms of hypopituitarism overlap with symptoms occurring in patients with chronic TBI, i.e. they have lower scores on neuropsychological examinations (cognitive disability) and have more symptoms of mental distress (depression and fatigue). The great challenges for the endocrinologist are: (1) detection of hypopituitarism in patients with TBI prospectively (in the acute phase and months to years after TBI), (2) assessment of the extent of cognitive impairment at baseline, and (3) monitoring of treatment effects (alteration of cognitive functioning and mental distress with hormone replacement therapy). Only few studies recently suggest that with growth hormone (rhGH) replacement in patients with chronic TBI and with abnormal GH secretion, cognitive performance may not change while symptoms related to depression and fatigue improve. Stagnation in post-TBI rehabilitation progress is recommended as a signal for clinical suspicion of neuroendocrine dysfunction. This remains a challenging area for more research.",
publisher = "Springer, New York",
journal = "Pituitary",
title = "Traumatic brain injury: neuropathological, neurocognitive and neurobehavioral sequelae",
pages = "282-270",
number = "3",
volume = "22",
doi = "10.1007/s11102-019-00957-9"
}

Pavlović, D., Pekić, S., Stojanović, M.,& Popović, V.. (2019). Traumatic brain injury: neuropathological, neurocognitive and neurobehavioral sequelae. in Pituitary
Springer, New York., 22(3), 270-282.
https://doi.org/10.1007/s11102-019-00957-9

Pavlović D, Pekić S, Stojanović M, Popović V. Traumatic brain injury: neuropathological, neurocognitive and neurobehavioral sequelae. in Pituitary. 2019;22(3):270-282.
doi:10.1007/s11102-019-00957-9 .

Pavlović, Dragan, Pekić, Sandra, Stojanović, Marko, Popović, Vera, "Traumatic brain injury: neuropathological, neurocognitive and neurobehavioral sequelae" in Pituitary, 22, no. 3 (2019):270-282,
https://doi.org/10.1007/s11102-019-00957-9 . .

TY  - JOUR
AU  - Pavlović, Dragan
PY  - 2019
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/1223
PB  - Univerzitet u Beogradu - Fakultet za specijalnu edukaciju i rehabilitaciju, Beograd
T2  - Specijalna edukacija i rehabilitacija
T1  - Neurodegenerativni poremecaji govora i jezika
T1  - Prikaz monografije Neurodegenerativni poremećaji govora i jezika - Mile Vuković: Neurodegenerativni poremećaji govora i jezika, Univerzitet u Beogradu, Fakultet za specijalnu edukaciju i rehabilitaciju, Beograd, 2019
EP  - 227
IS  - 2
SP  - 223
VL  - 18
DO  - 10.5937/specedreh18-23041
ER  - 

@article{
author = "Pavlović, Dragan",
year = "2019",
publisher = "Univerzitet u Beogradu - Fakultet za specijalnu edukaciju i rehabilitaciju, Beograd",
journal = "Specijalna edukacija i rehabilitacija",
title = "Neurodegenerativni poremecaji govora i jezika, Prikaz monografije Neurodegenerativni poremećaji govora i jezika - Mile Vuković: Neurodegenerativni poremećaji govora i jezika, Univerzitet u Beogradu, Fakultet za specijalnu edukaciju i rehabilitaciju, Beograd, 2019",
pages = "227-223",
number = "2",
volume = "18",
doi = "10.5937/specedreh18-23041"
}

Pavlović, D.. (2019). Neurodegenerativni poremecaji govora i jezika. in Specijalna edukacija i rehabilitacija
Univerzitet u Beogradu - Fakultet za specijalnu edukaciju i rehabilitaciju, Beograd., 18(2), 223-227.
https://doi.org/10.5937/specedreh18-23041

Pavlović D. Neurodegenerativni poremecaji govora i jezika. in Specijalna edukacija i rehabilitacija. 2019;18(2):223-227.
doi:10.5937/specedreh18-23041 .

Pavlović, Dragan, "Neurodegenerativni poremecaji govora i jezika" in Specijalna edukacija i rehabilitacija, 18, no. 2 (2019):223-227,
https://doi.org/10.5937/specedreh18-23041 . .