Odlike starenja osoba sa cerebralnom paralizom i multiplom sklerozom

Abstract

Starenje je prirodan doživotni proces, koji nosi sa sobom biopsihosocijalne promene. Na biološkom nivou dovodi do progresivnog, univerzalnog sniženja funkcione rezerve, a potom i funkcije organizma, ali nije sinonim za bolesti i nesposobnost. Međutim, tokom starenja se povećava rizik od razvitka bolesti, a mortalitet raste eksponencijalno sa godinama. Proces starenja moguće je sagledati kroz analizu bioloških parametara kako kod zdravih, tako i kod osoba sa motoričkim smetnjama i poremećajima. U detekciji patofzioloških poremećaja u različitim oboljenjima bubrega i mokraćnih puteva pregled mokraće predstavlja osnovni i nezaobilazni pregled. Pored toga, poznato je da se vrednosti krvnog pritiska povećavaju sa godinama starosti. Takođe, procena stanja uhranjenosti i, još više, raspodele telesne masti, danas ima veliki klinički značaj, jer ima sve više dokaza o tome da je gojaznost i to prvenstveno abnormalna gojaznost, značajan nezavisni faktor rizika za razvoj kardiovaskularnih bolesti. Osim toga, poznato je da se kod gojaznih osoba češće javljaju pojedini glavni faktori rizika za hipertenziju, hiperlipidemiju i šećernu bolest. Svi ovi faktori, pojedinačno, ali i u medjusobnom sadejstvu, utiču na proces starenja. U ovom radu praćeni su pojedini zdravstveni parametri, poput biohemijskih karakteristika urina, krvnog pritiska i telesne mase, koji mogu poslužiti kao indikatori procesa starenja kako kod tipične zdrave populacije tako i kod osoba koje pate od cerebralne paralize i multiple paralize. Pretpostavljeno je da se na osnovu stanja ovih parametara može pratiti brzina starenja, opšte zdravstveno stanje i sklonost ka razvoju bolesti kod populacije sa motoričkim smetnjama i poremećajima.

Aging is a natural lifelong process that carries with it a biopsychosocial change. At the biological level it leads to a progressive, universal reduction of the functional reserve, and then to the functions of the organism, but is not synonymous with disease and incompetence. However, during aging, the risk of developing a disease increases, and mortality increases exponentially with age. The aging process can be seen through the analysis of biological parameters in healthy, as well as in people with motor disorders and disorders. In the detection of pathophysiological disorders in various diseases of the kidneys and urinary tract, urine examination is a basic and unavoidable overview. In addition, it is known that blood pressure values increase with age. Also, assessing the state of nutrition and, more importantly, the distribution of body fat, today has a great clinical significance, as there is increasing evidence that obesity is primarily abnormal obesity, a significant independent risk factor for the development of cardiovascular diseases. In addition, it is known that certain major risk factors for hypertension, hyperlipidemia and diabetes are more common in obese people. All these factors, individually, but also in mutual cooperation, affect the aging process. In this paper, certain health parameters, such as biochemical characteristics of urine, blood pressure and body weight, can be used as indicators of the aging process both in the typical healthy population and in people suffering from cerebral palsy and multiple paralysis. It is assumed that based on the state of these parameters, the rate of aging, general health condition and the tendency to develop the disease in the population with motor disorders and disorders can be monitored.