Vitamin B1, eye and brain

Abstract

Vitamin B1 (aneurin, thiamine) is a water-soluble vitamin necessary for the normal function of the nervous system, visual system and heart and is part of important enzymes in the body. Thiamine enables the normal use of glucose, other carbohydrates and proteins, and enables the supply of energy to the organism. The main sources of thiamine are exogenous and small amounts are synthesized by microorganisms of the human intestinal microbiome. Vitamin B1 cannot accumulate in the body, so signs of deficiency are quickly manifested. Hypovitaminosis B1 is seen in chronic ethyl abuse, persistent vomiting (as in some pregnant women) or after bariatric surgical procedures, but in a mild form it is present in the general population. Normal daily needs for vitamin B1 depend on calorie intake, and 0.4 mg should be ingested for every 1000 kcal.

Vitamin B1 (aneurin, tiamin) rastvorljiv je u vodi, neopho- dan je za normalno funkcionisanje nervnog sistema, organa vida i srca i deo je važnih enzima u telu. Tiamin omogućava normalnu upotrebu glukoze, drugih ugljenih hidrata i pro- teina i snabdevanje organizma energijom. Glavni izvori tiamina su egzogeni i male količine sinte- tišu mikroorganizmi ljudskog crevnog mikrobioma. Vitamin B1 se ne može nakupljati u telu, pa se znakovi ne- dostatka brzo manifestuju. Hipovitaminoza B1 se opaža kod hronične zloupotrebe alkohola, upornog povraćanja (kao kod nekih trudnica) ili posle barijatrijskih hirur- ških procedura, ali u blagom obliku je prisutna i u opštoj populaciji. Normalne dnevne potrebe za vitaminom B1 zavise od unosa kalorija, pa na svakih 1000 kcal treba unetiti 0,4 mg ovog vitamina.