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The Yaa mutation promoting murine lupus causes defective development of marginal zone B cells
(Amer Assoc Immunologists, Bethesda, 2003)
The accelerated development of systemic lupus erythematosus (SLE) in BXSB male mice is associated with the presence of an as yet unidentified mutant gene, Yaa (Y-linked autoimmune acceleration). In view of a possible role ...