The aim of this study was to assess the role of the Addenbrooke's cognitive examination test (ACE-R) in the evaluation of cognitive status in migraineurs interictally. A total of 44 adolescent patients and 44 healthy controls, matched by age and gender, have undergone ACE-R testing. Migraineurs were additionally questioned about migraine aura features and presence of higher cortical dysfunctions (HCD) during an aura. According to the questionnaire results, patients were subsequently divided into HCD and Non-HCD group. ACE-R scores of migraine patients were significantly lower than in healthy controls (93.68 +/- 3.64 vs 96.91 +/- 2.49; t = 4.852, p lt 0.001). Also, subscores of memory and verbal fluency were significantly higher in the control population. There was no correlation of HCD occurrence with cognitive examination score, although Non-HCD subgroup achieved better score (93.13 +/- 3.91 vs 94.29 +/- 3.30; t = 1.053, p = 0.298). Findings have shown that migraineurs get lower ACE...-R test scores, with a tendency to have a poorer outcome in more complex aura. Also, our study has revealed that the ACE-R test is an easily administered test for brief assessment of cognitive status in migraineurs. Future perspectives could be further evaluation of ACE-R test in larger sample size and the impact of migraine with aura on cognitive function in adolescents.
Keywords:
Migraine with aura / Adolescents / Neuropsychological testing
TY - JOUR
AU - Petrušić, Igor
AU - Pavlovski, Vera
AU - Savković, Zorica
AU - Vučinić, Dragana
AU - Filipović, Branislav
AU - Jančić, Jasna
PY - 2017
UR - http://rfasper.fasper.bg.ac.rs/handle/123456789/1066
AB - The aim of this study was to assess the role of the Addenbrooke's cognitive examination test (ACE-R) in the evaluation of cognitive status in migraineurs interictally. A total of 44 adolescent patients and 44 healthy controls, matched by age and gender, have undergone ACE-R testing. Migraineurs were additionally questioned about migraine aura features and presence of higher cortical dysfunctions (HCD) during an aura. According to the questionnaire results, patients were subsequently divided into HCD and Non-HCD group. ACE-R scores of migraine patients were significantly lower than in healthy controls (93.68 +/- 3.64 vs 96.91 +/- 2.49; t = 4.852, p lt 0.001). Also, subscores of memory and verbal fluency were significantly higher in the control population. There was no correlation of HCD occurrence with cognitive examination score, although Non-HCD subgroup achieved better score (93.13 +/- 3.91 vs 94.29 +/- 3.30; t = 1.053, p = 0.298). Findings have shown that migraineurs get lower ACE-R test scores, with a tendency to have a poorer outcome in more complex aura. Also, our study has revealed that the ACE-R test is an easily administered test for brief assessment of cognitive status in migraineurs. Future perspectives could be further evaluation of ACE-R test in larger sample size and the impact of migraine with aura on cognitive function in adolescents.
PB - Springer Heidelberg, Heidelberg
T2 - Acta Neurologica Belgica
T1 - Addenbrooke's cognitive examination test for brief cognitive assessment of adolescents suffering from migraine with aura
EP - 102
IS - 1
SP - 97
VL - 117
DO - 10.1007/s13760-016-0655-9
ER -
@article{
author = "Petrušić, Igor and Pavlovski, Vera and Savković, Zorica and Vučinić, Dragana and Filipović, Branislav and Jančić, Jasna",
year = "2017",
abstract = "The aim of this study was to assess the role of the Addenbrooke's cognitive examination test (ACE-R) in the evaluation of cognitive status in migraineurs interictally. A total of 44 adolescent patients and 44 healthy controls, matched by age and gender, have undergone ACE-R testing. Migraineurs were additionally questioned about migraine aura features and presence of higher cortical dysfunctions (HCD) during an aura. According to the questionnaire results, patients were subsequently divided into HCD and Non-HCD group. ACE-R scores of migraine patients were significantly lower than in healthy controls (93.68 +/- 3.64 vs 96.91 +/- 2.49; t = 4.852, p lt 0.001). Also, subscores of memory and verbal fluency were significantly higher in the control population. There was no correlation of HCD occurrence with cognitive examination score, although Non-HCD subgroup achieved better score (93.13 +/- 3.91 vs 94.29 +/- 3.30; t = 1.053, p = 0.298). Findings have shown that migraineurs get lower ACE-R test scores, with a tendency to have a poorer outcome in more complex aura. Also, our study has revealed that the ACE-R test is an easily administered test for brief assessment of cognitive status in migraineurs. Future perspectives could be further evaluation of ACE-R test in larger sample size and the impact of migraine with aura on cognitive function in adolescents.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Acta Neurologica Belgica",
title = "Addenbrooke's cognitive examination test for brief cognitive assessment of adolescents suffering from migraine with aura",
pages = "102-97",
number = "1",
volume = "117",
doi = "10.1007/s13760-016-0655-9"
}
Petrušić, I., Pavlovski, V., Savković, Z., Vučinić, D., Filipović, B.,& Jančić, J.. (2017). Addenbrooke's cognitive examination test for brief cognitive assessment of adolescents suffering from migraine with aura. in Acta Neurologica Belgica
Springer Heidelberg, Heidelberg., 117(1), 97-102.
https://doi.org/10.1007/s13760-016-0655-9
Petrušić I, Pavlovski V, Savković Z, Vučinić D, Filipović B, Jančić J. Addenbrooke's cognitive examination test for brief cognitive assessment of adolescents suffering from migraine with aura. in Acta Neurologica Belgica. 2017;117(1):97-102.
doi:10.1007/s13760-016-0655-9 .
Petrušić, Igor, Pavlovski, Vera, Savković, Zorica, Vučinić, Dragana, Filipović, Branislav, Jančić, Jasna, "Addenbrooke's cognitive examination test for brief cognitive assessment of adolescents suffering from migraine with aura" in Acta Neurologica Belgica, 117, no. 1 (2017):97-102,
https://doi.org/10.1007/s13760-016-0655-9 . .
