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Differential activation of anti-erythrocyte and anti-DNA autoreactive B lymphocytes by the Yaa mutation
(Amer Assoc Immunologists, Bethesda, 2005)
An as-yet-unidentified mutation, Y-linked autoimmune acceleration (Yaa), is responsible for the accelerated development of lupus-like autoimmune syndrome in mice. In view of a possible role for Yaa as a positive regulator ...
B cell hyperresponsiveness and expansion of mature follicular B cells but not of marginal zone B cells in NFATc2/c3 double-deficient mice
(Amer Assoc Immunologists, Bethesda, 2005)
Marginal zone (MZ) B cells and peritoneal B-I cells provide a first defense system of thymus-independent Ab responses against foreign pathogens and therefore share a number of functional properties. Recently, development ...