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Intellectual disability and development of dementia: dementia in persons with down syndrome

dc.contributorAnđelković Marija
dc.contributorSretenović Ivana
dc.creatorPavlović, Aleksandra
dc.creatorPavlović, Dragan
dc.date.accessioned2021-09-21T09:11:55Z
dc.date.available2021-09-21T09:11:55Z
dc.date.issued2020
dc.identifier.isbn978-86-6203-145-7
dc.identifier.urihttp://www.icf.fasper.bg.ac.rs/zbornici/20201221_1-ZBORNIK-RADOVA-SKUP-NAC_2020.pdf
dc.identifier.urihttp://rfasper.fasper.bg.ac.rs/handle/123456789/3467
dc.description.abstractAdults with Down syndrome are at an increased risk of developing early onset Alzheimer’s diseasе. Dementia is typically preceded by prodromal pre-clinical phase. Pathohistological characteristics of Alzheimer’s diseasе are universally present by the fifth decade in Down syndrome patients. Trajectories of cognitive decline associated with dementia in Down syndrome population are not fully described. Having in mind pre-existing cognitive difficulties, early dementia signs may be overlooked or misdiagnosed, missing the opportunity for the early use of pharmacological and psychosocial interventions. Down syndrome population could be a target for investigation of preventive and therapeutic measures in management of Alzheimer’s diseasе. World Heаlth Organisation called for inclusion of intellectual disability in national dementia plans.sr
dc.description.abstractOdrasle osobe sa Daunovim sindromom su u velikom riziku za razvoj Alchajmerove bolesti ranog početka. Demenciji prethodi period prodromalne, pre-kliničke faze. Histopatološki nalazi karakteristični za Alchajmerovu bolest su gotovo pravilo kod osoba sa Daunovim sindromom u petoj deceniji života. Trajektorije kognitivnog propadanja kod populacije sa Daunovim sindromom nisu u potpunosti definisane. Budući da kod ovih osoba već postoji intelektu- alna ometenost, suptilni rani znaci kognitivnog pada se mogu prevideti ili pogrešno dijagnostikovati čime se propušta prilika za pravovremenu pri- menu farmakoloških i psihosocijalnih intervencija. Populacija sa Daunovim sindromom bi mogla biti ciljna za ispitivanje preventivnih i terapijski mera za nastanak Alchajmerove bolesti. Iz ovih razloga, Svetska zdravstvena organizacija je pozvala na uključivanje intelektualne ometenosti u nacional- ne planove za demenciju.sr
dc.language.isosrsr
dc.publisherUniverzitet u Beogradu - Fakultet za specijalnu edukaciju i rehabilitacijusr
dc.rightsopenAccesssr
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceNacionalni naučni skup „Evaluacija efekata inkluzivnog obrazovanja u republici Srbiji” - Zbornik radovasr
dc.subjectDown syndromesr
dc.subjectintellectual disabilitysr
dc.subjectcognitive declinesr
dc.subjectdementiasr
dc.subjectAlzheimer’s diseasesr
dc.subjectDaunov sindromsr
dc.subjectintelektualna ometenostsr
dc.subjectkognitivni padsr
dc.subjectdemencijasr
dc.subjectAlchajmerova bolestsr
dc.titleintelektualna ometenost i razvoj demencije: demencija kod osoba sa daunovim sindromomsr
dc.titleIntellectual disability and development of dementia: dementia in persons with down syndromesr
dc.typeconferenceObjectsr
dc.rights.licenseBY-SAsr
dc.citation.epage223
dc.citation.spage217
dc.identifier.fulltexthttp://rfasper.fasper.bg.ac.rs/bitstream/id/2677/bitstream_2677.pdf
dc.type.versionpublishedVersionsr


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