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c-MYC activation impairs the NF-kappa B and the interferon response: Implications for the pathogenesis of Burkitt's lymphoma
(Wiley-Liss, Hoboken, 2007)
Deregulation of the proto-oncogene c-myc is a key event in the pathogenesis of many tumors. A paradigm is the activation of the c-myc gene by chromosomal translocations in Burkitt lymphoma (BL). Despite expression of a ...
Differential activation of anti-erythrocyte and anti-DNA autoreactive B lymphocytes by the Yaa mutation
(Amer Assoc Immunologists, Bethesda, 2005)
An as-yet-unidentified mutation, Y-linked autoimmune acceleration (Yaa), is responsible for the accelerated development of lupus-like autoimmune syndrome in mice. In view of a possible role for Yaa as a positive regulator ...
Reduction of marginal zone B cells in CD22-deficient mice
(Wiley-V C H Verlag Gmbh, Weinheim, 2002)
CD22 is a B cell-specific member of the immunoglobulin superfamily and binds to sialic acid. CD22 inhibits B cell receptor signaling. Mice deficient for CD22 show a largely normal B cell development. Here, we have performed ...
Conditions of living and social skills of children with mild intellectual disability
(Wiley, Hoboken, 2006)
B cell hyperresponsiveness and expansion of mature follicular B cells but not of marginal zone B cells in NFATc2/c3 double-deficient mice
(Amer Assoc Immunologists, Bethesda, 2005)
Marginal zone (MZ) B cells and peritoneal B-I cells provide a first defense system of thymus-independent Ab responses against foreign pathogens and therefore share a number of functional properties. Recently, development ...
Verbal abilities in patients with Noonan syndrome
(Blackwell Publishing, Oxford, 2006)
Articulation characteristics of developmental verbal apraxia
(Nature Publishing Group, New York, 2009)