TY  - JOUR
AU  - Milovanović, Maja
AU  - Radivojević, Vlada
AU  - Radosavljev-Kirćanski, Jelena
AU  - Grujicić, Roberto
AU  - Tošković, Oliver
AU  - Aleksić-Hil, Olivera
AU  - Pejović-Milovančević, Milica
PY  - 2019
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/1203
AB  - Purpose: The purpose of this study was to determine the prevalence of epilepsy and subclinical epileptiform abnormalities in children with autism spectrum disorder (ASD), and to investigate its effects on core autistic symptoms and adaptive behavior skills. Methods: Patients with diagnosis of ASD who met full criteria on Autism Diagnostic Interview-Revised (ADI-R) were included in the study. Adaptive behavior skills were assessed by Vineland Adaptive Behavior Scale-II (VABS-II). Clinical assessment for epilepsy and video electroencephalography (EEG) (v-EEG) examinations during wakefulness and/or sleep were prospectively performed in all patients. Results: A total of 112 patients with diagnosis of ASD of mean age 6.58 +/- 3.72 were included in the study. Based on clinical and v-EEG assessments, three groups of patients were defined: 1) patients with epilepsy (n = 17; 15.2%); 2) patients with epileptiform discharges in absence of clinical seizures (n = 14; 12.5%); 3) patients without epilepsy and without epileptiform discharges ( n = 81; 72.3%). There were no significant differences between three groups of patients on ADI-R subscores. Speech development was also not significantly related to epilepsy. There was a slight tendency of the VABS-II motor skills score to be higher in the group of patients with autism without clinical diagnosis of epilepsy and without subclinical epileptiform discharges (p  lt  0.05) in comparison with the two other groups. According to this tendency, we might claim that patients with higher scores on motor skills could have 0.88 times lower odds for having epileptiform EEG activity. Conclusions: According to our results, we were not able to detect differences in the ADI-R between the three populations with ASD, all with unknown etiology. Epilepsy, as well as subdinical epileptic discharges, showed small effects on Motor Skills in patients with autism, and had no effect on adaptive behavior Communication/Socialization/Daily Living Skills.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Epilepsy & Behavior
T1  - Epilepsy and interictal epileptiform activity in patients with autism spectrum disorders
EP  - 52
SP  - 45
VL  - 92
DO  - 10.1016/j.yebeh.2018.12.011
ER  - 

@article{
author = "Milovanović, Maja and Radivojević, Vlada and Radosavljev-Kirćanski, Jelena and Grujicić, Roberto and Tošković, Oliver and Aleksić-Hil, Olivera and Pejović-Milovančević, Milica",
year = "2019",
abstract = "Purpose: The purpose of this study was to determine the prevalence of epilepsy and subclinical epileptiform abnormalities in children with autism spectrum disorder (ASD), and to investigate its effects on core autistic symptoms and adaptive behavior skills. Methods: Patients with diagnosis of ASD who met full criteria on Autism Diagnostic Interview-Revised (ADI-R) were included in the study. Adaptive behavior skills were assessed by Vineland Adaptive Behavior Scale-II (VABS-II). Clinical assessment for epilepsy and video electroencephalography (EEG) (v-EEG) examinations during wakefulness and/or sleep were prospectively performed in all patients. Results: A total of 112 patients with diagnosis of ASD of mean age 6.58 +/- 3.72 were included in the study. Based on clinical and v-EEG assessments, three groups of patients were defined: 1) patients with epilepsy (n = 17; 15.2%); 2) patients with epileptiform discharges in absence of clinical seizures (n = 14; 12.5%); 3) patients without epilepsy and without epileptiform discharges ( n = 81; 72.3%). There were no significant differences between three groups of patients on ADI-R subscores. Speech development was also not significantly related to epilepsy. There was a slight tendency of the VABS-II motor skills score to be higher in the group of patients with autism without clinical diagnosis of epilepsy and without subclinical epileptiform discharges (p  lt  0.05) in comparison with the two other groups. According to this tendency, we might claim that patients with higher scores on motor skills could have 0.88 times lower odds for having epileptiform EEG activity. Conclusions: According to our results, we were not able to detect differences in the ADI-R between the three populations with ASD, all with unknown etiology. Epilepsy, as well as subdinical epileptic discharges, showed small effects on Motor Skills in patients with autism, and had no effect on adaptive behavior Communication/Socialization/Daily Living Skills.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Epilepsy & Behavior",
title = "Epilepsy and interictal epileptiform activity in patients with autism spectrum disorders",
pages = "52-45",
volume = "92",
doi = "10.1016/j.yebeh.2018.12.011"
}

Milovanović, M., Radivojević, V., Radosavljev-Kirćanski, J., Grujicić, R., Tošković, O., Aleksić-Hil, O.,& Pejović-Milovančević, M.. (2019). Epilepsy and interictal epileptiform activity in patients with autism spectrum disorders. in Epilepsy & Behavior
Academic Press Inc Elsevier Science, San Diego., 92, 45-52.
https://doi.org/10.1016/j.yebeh.2018.12.011

Milovanović M, Radivojević V, Radosavljev-Kirćanski J, Grujicić R, Tošković O, Aleksić-Hil O, Pejović-Milovančević M. Epilepsy and interictal epileptiform activity in patients with autism spectrum disorders. in Epilepsy & Behavior. 2019;92:45-52.
doi:10.1016/j.yebeh.2018.12.011 .

Milovanović, Maja, Radivojević, Vlada, Radosavljev-Kirćanski, Jelena, Grujicić, Roberto, Tošković, Oliver, Aleksić-Hil, Olivera, Pejović-Milovančević, Milica, "Epilepsy and interictal epileptiform activity in patients with autism spectrum disorders" in Epilepsy & Behavior, 92 (2019):45-52,
https://doi.org/10.1016/j.yebeh.2018.12.011 . .

TY  - BOOK
AU  - Veljković, Lela
AU  - Glumbić, Nenad
AU  - Kojović, Biljana
AU  - Lakić, Aneta
AU  - Marković, Jasminka
AU  - Petrović, Vesna
AU  - Radosavljev-Kirćanski, Jelena
AU  - Rudić, Nenad
AU  - Stanković, Miodrag
AU  - Šulović, Mirjana
AU  - Zajeganović-Jakovljević, Jelena
AU  - Zdravković, Snežana
PY  - 2018
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/2865
PB  - Ministarstvo zdravlja Republike Srbije
T1  - Smernice za skrining, dijagnostiku i intervencije kod dece sa poremećajem iz spektra autizma
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_2865
ER  - 

@book{
author = "Veljković, Lela and Glumbić, Nenad and Kojović, Biljana and Lakić, Aneta and Marković, Jasminka and Petrović, Vesna and Radosavljev-Kirćanski, Jelena and Rudić, Nenad and Stanković, Miodrag and Šulović, Mirjana and Zajeganović-Jakovljević, Jelena and Zdravković, Snežana",
year = "2018",
publisher = "Ministarstvo zdravlja Republike Srbije",
title = "Smernice za skrining, dijagnostiku i intervencije kod dece sa poremećajem iz spektra autizma",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_2865"
}

Veljković, L., Glumbić, N., Kojović, B., Lakić, A., Marković, J., Petrović, V., Radosavljev-Kirćanski, J., Rudić, N., Stanković, M., Šulović, M., Zajeganović-Jakovljević, J.,& Zdravković, S.. (2018). Smernice za skrining, dijagnostiku i intervencije kod dece sa poremećajem iz spektra autizma. 
Ministarstvo zdravlja Republike Srbije..
https://hdl.handle.net/21.15107/rcub_rfasper_2865

Veljković L, Glumbić N, Kojović B, Lakić A, Marković J, Petrović V, Radosavljev-Kirćanski J, Rudić N, Stanković M, Šulović M, Zajeganović-Jakovljević J, Zdravković S. Smernice za skrining, dijagnostiku i intervencije kod dece sa poremećajem iz spektra autizma. 2018;.
https://hdl.handle.net/21.15107/rcub_rfasper_2865 .

Veljković, Lela, Glumbić, Nenad, Kojović, Biljana, Lakić, Aneta, Marković, Jasminka, Petrović, Vesna, Radosavljev-Kirćanski, Jelena, Rudić, Nenad, Stanković, Miodrag, Šulović, Mirjana, Zajeganović-Jakovljević, Jelena, Zdravković, Snežana, "Smernice za skrining, dijagnostiku i intervencije kod dece sa poremećajem iz spektra autizma" (2018),
https://hdl.handle.net/21.15107/rcub_rfasper_2865 .