Lukovac, Tanja

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  • Lukovac, Tanja (4)

Author's Bibliography

Serum Biomarker Analysis in Pediatric ADHD: Implications of Homocysteine, Vitamin B12, Vitamin D, Ferritin, and Iron Levels

Lukovac, Tanja; Hil, Olivera Aleksić; Popović, Milka; Jovanović, Vitomir; Savić, Tatjana; Pavlović, Aleksandra M.; Pavlović, Dragan

(MDPI, 2024)

TY  - JOUR
AU  - Lukovac, Tanja
AU  - Hil, Olivera Aleksić
AU  - Popović, Milka
AU  - Jovanović, Vitomir
AU  - Savić, Tatjana
AU  - Pavlović, Aleksandra M.
AU  - Pavlović, Dragan
PY  - 2024
UR  - https://www.mdpi.com/2227-9067/11/4/497
UR  - internal-pdf://2348/Lukovac et al. - 2024 - Serum Biomarker Analysis in Pediatric ADHD Implic.pdf
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/5429
AB  - The current diagnosis of attention deficit hyperactivity disorder (ADHD) is based on history, clinical observation, and behavioral tests. There is a high demand to find biomarkers for the diagnosis of ADHD. The aim of this study is to analyze the serum profiles of several biomarkers, including homocysteine (Hcy), vitamin B12, vitamin D, ferritin, and iron, in a cohort of 133 male subjects (6.5–12.5 years), including 67 individuals with an ADHD diagnosis based on DSM-V criteria and 66 age-matched healthy boys (healthy controls, HC). Assessments for ADHD included the Iowa Conners’ Teacher Rating Scale (CPRS) and the ADHDT test, as well as cognitive assessments using the Wechsler Intelligence Scale for Children-Revised (WISC-R) and the TROG-2 language comprehension test. Hcy and iron were quantified using spectrophotometry, while vitamin B12 and total 25-hydroxy vitamin D levels were determined using an electrochemiluminescence immunoassay (ECLIA) and ferritin was measured using a particle-enhanced immunoturbidimetric assay. The results showed significantly increased Hcy levels and decreased vitamin B12 levels in ADHD patients compared to HCs. Multiple logistic regression analysis indicated that Hcy is a potential prognostic indicator for ADHD. These results suggest that elevated homocysteine and decreased vitamin B12 may serve as markers for the diagnosis and prognosis of ADHD.
PB  - MDPI
T2  - Children
T2  - Children
T1  - Serum Biomarker Analysis in Pediatric ADHD: Implications of Homocysteine, Vitamin B12, Vitamin D, Ferritin, and Iron Levels
IS  - 4
SP  - 497
VL  - 11
DO  - 10.3390/children11040497
ER  - 
@article{
author = "Lukovac, Tanja and Hil, Olivera Aleksić and Popović, Milka and Jovanović, Vitomir and Savić, Tatjana and Pavlović, Aleksandra M. and Pavlović, Dragan",
year = "2024",
abstract = "The current diagnosis of attention deficit hyperactivity disorder (ADHD) is based on history, clinical observation, and behavioral tests. There is a high demand to find biomarkers for the diagnosis of ADHD. The aim of this study is to analyze the serum profiles of several biomarkers, including homocysteine (Hcy), vitamin B12, vitamin D, ferritin, and iron, in a cohort of 133 male subjects (6.5–12.5 years), including 67 individuals with an ADHD diagnosis based on DSM-V criteria and 66 age-matched healthy boys (healthy controls, HC). Assessments for ADHD included the Iowa Conners’ Teacher Rating Scale (CPRS) and the ADHDT test, as well as cognitive assessments using the Wechsler Intelligence Scale for Children-Revised (WISC-R) and the TROG-2 language comprehension test. Hcy and iron were quantified using spectrophotometry, while vitamin B12 and total 25-hydroxy vitamin D levels were determined using an electrochemiluminescence immunoassay (ECLIA) and ferritin was measured using a particle-enhanced immunoturbidimetric assay. The results showed significantly increased Hcy levels and decreased vitamin B12 levels in ADHD patients compared to HCs. Multiple logistic regression analysis indicated that Hcy is a potential prognostic indicator for ADHD. These results suggest that elevated homocysteine and decreased vitamin B12 may serve as markers for the diagnosis and prognosis of ADHD.",
publisher = "MDPI",
journal = "Children, Children",
title = "Serum Biomarker Analysis in Pediatric ADHD: Implications of Homocysteine, Vitamin B12, Vitamin D, Ferritin, and Iron Levels",
number = "4",
pages = "497",
volume = "11",
doi = "10.3390/children11040497"
}
Lukovac, T., Hil, O. A., Popović, M., Jovanović, V., Savić, T., Pavlović, A. M.,& Pavlović, D.. (2024). Serum Biomarker Analysis in Pediatric ADHD: Implications of Homocysteine, Vitamin B12, Vitamin D, Ferritin, and Iron Levels. in Children
MDPI., 11(4), 497.
https://doi.org/10.3390/children11040497
Lukovac T, Hil OA, Popović M, Jovanović V, Savić T, Pavlović AM, Pavlović D. Serum Biomarker Analysis in Pediatric ADHD: Implications of Homocysteine, Vitamin B12, Vitamin D, Ferritin, and Iron Levels. in Children. 2024;11(4):497.
doi:10.3390/children11040497 .
Lukovac, Tanja, Hil, Olivera Aleksić, Popović, Milka, Jovanović, Vitomir, Savić, Tatjana, Pavlović, Aleksandra M., Pavlović, Dragan, "Serum Biomarker Analysis in Pediatric ADHD: Implications of Homocysteine, Vitamin B12, Vitamin D, Ferritin, and Iron Levels" in Children, 11, no. 4 (2024):497,
https://doi.org/10.3390/children11040497 . .
5

Serum levels of glucose, thyroid stimulating hormone, and free thyroxine in boys diagnosed with attention deficit hyperactivity disorder: a cross-sectional pilot study

Lukovac, Tanja; Hil, Olivera Aleksić; Popović, Milka; Savić, Tatjana; Pavlović, Aleksandra; Pavlović, Dragan

(BMC, 2024)

TY  - JOUR
AU  - Lukovac, Tanja
AU  - Hil, Olivera Aleksić
AU  - Popović, Milka
AU  - Savić, Tatjana
AU  - Pavlović, Aleksandra
AU  - Pavlović, Dragan
PY  - 2024
UR  - https://doi.org/10.1186/s12883-024-03563-w
UR  - internal-pdf://2343/Lukovac et al. - 2024 - Serum levels of glucose, thyroid stimulating hormo.pdf
UR  - internal-pdf://2344/s12883-024-03563-w.html
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/5428
AB  - Although attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, its aetiology remains unclear. We aimed to establish a relationship between ADHD diagnosis and serum levels of glucose, free thyroxine (FT4), and thyroid stimulating hormone (TSH) in primary school aged boys.
PB  - BMC
T2  - BMC Neurology
T2  - BMC NeurologyBMC Neurology
T1  - Serum levels of glucose, thyroid stimulating hormone, and free thyroxine in boys diagnosed with attention deficit hyperactivity disorder: a cross-sectional pilot study
IS  - 1
SP  - 76
VL  - 24
DO  - 10.1186/s12883-024-03563-w
ER  - 
@article{
author = "Lukovac, Tanja and Hil, Olivera Aleksić and Popović, Milka and Savić, Tatjana and Pavlović, Aleksandra and Pavlović, Dragan",
year = "2024",
abstract = "Although attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, its aetiology remains unclear. We aimed to establish a relationship between ADHD diagnosis and serum levels of glucose, free thyroxine (FT4), and thyroid stimulating hormone (TSH) in primary school aged boys.",
publisher = "BMC",
journal = "BMC Neurology, BMC NeurologyBMC Neurology",
title = "Serum levels of glucose, thyroid stimulating hormone, and free thyroxine in boys diagnosed with attention deficit hyperactivity disorder: a cross-sectional pilot study",
number = "1",
pages = "76",
volume = "24",
doi = "10.1186/s12883-024-03563-w"
}
Lukovac, T., Hil, O. A., Popović, M., Savić, T., Pavlović, A.,& Pavlović, D.. (2024). Serum levels of glucose, thyroid stimulating hormone, and free thyroxine in boys diagnosed with attention deficit hyperactivity disorder: a cross-sectional pilot study. in BMC Neurology
BMC., 24(1), 76.
https://doi.org/10.1186/s12883-024-03563-w
Lukovac T, Hil OA, Popović M, Savić T, Pavlović A, Pavlović D. Serum levels of glucose, thyroid stimulating hormone, and free thyroxine in boys diagnosed with attention deficit hyperactivity disorder: a cross-sectional pilot study. in BMC Neurology. 2024;24(1):76.
doi:10.1186/s12883-024-03563-w .
Lukovac, Tanja, Hil, Olivera Aleksić, Popović, Milka, Savić, Tatjana, Pavlović, Aleksandra, Pavlović, Dragan, "Serum levels of glucose, thyroid stimulating hormone, and free thyroxine in boys diagnosed with attention deficit hyperactivity disorder: a cross-sectional pilot study" in BMC Neurology, 24, no. 1 (2024):76,
https://doi.org/10.1186/s12883-024-03563-w . .
1
1

Attention deficit hyperactivity disorder and micronutrities

Lukovac, Tanja; Pavlović, Dragan

(Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd, 2019)

TY  - JOUR
AU  - Lukovac, Tanja
AU  - Pavlović, Dragan
PY  - 2019
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/1182
AB  - Attention Deficit Hyperactivity Disorder (ADHD) is a clinical behavioral disorder in children marked by an ongoing pattern of inattention and/or hyperactivity-impulsivity in all situations, which occurs early and persists through time. The aim of the paper is to review the previous scientific studies in which the issue of association between the attention deficit and hyperactivity and micronutrients (vitamins and minerals) was addressed, by examining the available literature. Numerous studies have correlated the diet, that is, nutritional deficits with the ADHD. Deficiency of fatty acids, as well as the lack of zinc and iron, were the most frequently observed. Some studies have reported a significant effect of precisely defined doses of vitamins D and B12, while others have determined the existence of a positive correlation between the severity of ADHD symptoms and the level of nutritional deficiency. Overall, the duction of appropriate nutritional and/ or supplementation regimens could be a good option for reducing the ADHD symptoms. As a practical contribution, all information on possible unwanted outcomes of micronutrient imbalance should be available to parents of children with ADHD and experts directly involved in working with these families. Larger studies are needed to determine the optimal multifactorial treatment that includes, in addition to medications and behavioral work, balanced nutrition with the necessary supplementation.
AB  - Poremećaj pažnje sa hiperaktivnošću (eng. Attention Deficit Hyperactivity Disorder - ADHD) je klinički poremećaj ponašanja kod dece kod koga se javlja nedostatak pažnje i/ili hiperaktivnost u svim situacijama, a koji se javlјa rano i perzistira kroz vreme. Cilј rada je da se uvidom u dostupnu literaturu, napravi pregled dosadašnjih naučnih radova u kojima je obrađivana problematika povezanosti deficita pažnje i hiperaktivnosti i mikronutrijenata: vitamina i minerala. Brojne studije dovele su u vezu ishranu, odnosno, nutricione deficite sa nastankom ADHD. Najčešće su uočeni deficiti masnih kiselina, kao i nedostatak cinka i gvožđa. Neke studije su izvestile o značajnom učinku precizno određenih doza vitamin D i B12, dok su druge utvrdile postojanje pozitivne korelacije između jačine ADHD simptoma i nivoa nutritivnog deficita. Sveukupno, uvođenje odgovarajućih režima ishrane i/ili suplementacije bi mogla biti dobra opcija za smanjenje simptoma ADHD. Kao praktični doprinos, potrebno je da sve informacije o mogućim neželјenim ishodima disbalansa mikronutrijenata budu dostupne roditelјima dece sa ADHD i stručnjacima neposredno uklјučenim u rad sa ovim porodicama. Potrebne su veće studije za određivanje optimalnog multifaktorskog tretmana koji uklјučuje, pored lekova i bihevioralnog rada, izbalansiranu ishranu sa potrebnom suplementacijom.
PB  - Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd
T2  - Engrami
T1  - Attention deficit hyperactivity disorder and micronutrities
T1  - Poremećaj pažnje sa hiperaktivnošću i mikronutritijenti
EP  - 59
IS  - 1
SP  - 46
VL  - 41
DO  - 10.5937/engrami1901046L
ER  - 
@article{
author = "Lukovac, Tanja and Pavlović, Dragan",
year = "2019",
abstract = "Attention Deficit Hyperactivity Disorder (ADHD) is a clinical behavioral disorder in children marked by an ongoing pattern of inattention and/or hyperactivity-impulsivity in all situations, which occurs early and persists through time. The aim of the paper is to review the previous scientific studies in which the issue of association between the attention deficit and hyperactivity and micronutrients (vitamins and minerals) was addressed, by examining the available literature. Numerous studies have correlated the diet, that is, nutritional deficits with the ADHD. Deficiency of fatty acids, as well as the lack of zinc and iron, were the most frequently observed. Some studies have reported a significant effect of precisely defined doses of vitamins D and B12, while others have determined the existence of a positive correlation between the severity of ADHD symptoms and the level of nutritional deficiency. Overall, the duction of appropriate nutritional and/ or supplementation regimens could be a good option for reducing the ADHD symptoms. As a practical contribution, all information on possible unwanted outcomes of micronutrient imbalance should be available to parents of children with ADHD and experts directly involved in working with these families. Larger studies are needed to determine the optimal multifactorial treatment that includes, in addition to medications and behavioral work, balanced nutrition with the necessary supplementation., Poremećaj pažnje sa hiperaktivnošću (eng. Attention Deficit Hyperactivity Disorder - ADHD) je klinički poremećaj ponašanja kod dece kod koga se javlja nedostatak pažnje i/ili hiperaktivnost u svim situacijama, a koji se javlјa rano i perzistira kroz vreme. Cilј rada je da se uvidom u dostupnu literaturu, napravi pregled dosadašnjih naučnih radova u kojima je obrađivana problematika povezanosti deficita pažnje i hiperaktivnosti i mikronutrijenata: vitamina i minerala. Brojne studije dovele su u vezu ishranu, odnosno, nutricione deficite sa nastankom ADHD. Najčešće su uočeni deficiti masnih kiselina, kao i nedostatak cinka i gvožđa. Neke studije su izvestile o značajnom učinku precizno određenih doza vitamin D i B12, dok su druge utvrdile postojanje pozitivne korelacije između jačine ADHD simptoma i nivoa nutritivnog deficita. Sveukupno, uvođenje odgovarajućih režima ishrane i/ili suplementacije bi mogla biti dobra opcija za smanjenje simptoma ADHD. Kao praktični doprinos, potrebno je da sve informacije o mogućim neželјenim ishodima disbalansa mikronutrijenata budu dostupne roditelјima dece sa ADHD i stručnjacima neposredno uklјučenim u rad sa ovim porodicama. Potrebne su veće studije za određivanje optimalnog multifaktorskog tretmana koji uklјučuje, pored lekova i bihevioralnog rada, izbalansiranu ishranu sa potrebnom suplementacijom.",
publisher = "Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd",
journal = "Engrami",
title = "Attention deficit hyperactivity disorder and micronutrities, Poremećaj pažnje sa hiperaktivnošću i mikronutritijenti",
pages = "59-46",
number = "1",
volume = "41",
doi = "10.5937/engrami1901046L"
}
Lukovac, T.,& Pavlović, D.. (2019). Attention deficit hyperactivity disorder and micronutrities. in Engrami
Klinički centar Srbije - Klinika za psihijatriju, Beograd i Udruženje psihijatara Srbije, Beograd., 41(1), 46-59.
https://doi.org/10.5937/engrami1901046L
Lukovac T, Pavlović D. Attention deficit hyperactivity disorder and micronutrities. in Engrami. 2019;41(1):46-59.
doi:10.5937/engrami1901046L .
Lukovac, Tanja, Pavlović, Dragan, "Attention deficit hyperactivity disorder and micronutrities" in Engrami, 41, no. 1 (2019):46-59,
https://doi.org/10.5937/engrami1901046L . .
1

Semantic abilities in children with reading disability

Golubović, Slavica; Lukovac, Tanja

(Wiley-Blackwell, Malden, 2011)

TY  - CONF
AU  - Golubović, Slavica
AU  - Lukovac, Tanja
PY  - 2011
UR  - http://rfasper.fasper.bg.ac.rs/handle/123456789/549
PB  - Wiley-Blackwell, Malden
C3  - European Journal of Neurology
T1  - Semantic abilities in children with reading disability
EP  - 143
SP  - 143
VL  - 18
UR  - https://hdl.handle.net/21.15107/rcub_rfasper_549
ER  - 
@conference{
author = "Golubović, Slavica and Lukovac, Tanja",
year = "2011",
publisher = "Wiley-Blackwell, Malden",
journal = "European Journal of Neurology",
title = "Semantic abilities in children with reading disability",
pages = "143-143",
volume = "18",
url = "https://hdl.handle.net/21.15107/rcub_rfasper_549"
}
Golubović, S.,& Lukovac, T.. (2011). Semantic abilities in children with reading disability. in European Journal of Neurology
Wiley-Blackwell, Malden., 18, 143-143.
https://hdl.handle.net/21.15107/rcub_rfasper_549
Golubović S, Lukovac T. Semantic abilities in children with reading disability. in European Journal of Neurology. 2011;18:143-143.
https://hdl.handle.net/21.15107/rcub_rfasper_549 .
Golubović, Slavica, Lukovac, Tanja, "Semantic abilities in children with reading disability" in European Journal of Neurology, 18 (2011):143-143,
https://hdl.handle.net/21.15107/rcub_rfasper_549 .